Skip to main content

Testosterone acetate

ADVERTISEMENT
Identification
Molecular formula
C21H30O3
CAS number
1045-69-8
IUPAC name
[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate
State
State

Testosterone acetate is a solid at room temperature.

Melting point (Celsius)
139.50
Melting point (Kelvin)
412.65
Boiling point (Celsius)
277.60
Boiling point (Kelvin)
550.75
General information
Molecular weight
330.46g/mol
Molar mass
330.4600g/mol
Density
1.0900g/cm3
Appearence

Testosterone acetate appears as a white crystalline powder. It is odorless and stable under normal conditions. Like many esters, it is often characterized by its crystalline structure when observed under appropriate conditions.

Comment on solubility

Solubility of [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate

The solubility characteristics of this compound, known for its complex stereochemistry and unique structure, can be intriguing. Due to its large and hydrophobic nature, it is generally considered to be:

  • Low solubility in water: The extensive hydrocarbon framework contributes to poor interaction with polar solvents, significantly limiting its solubility in aqueous environments.
  • Moderate to high solubility in organic solvents: It tends to exhibit better solubility profiles in organic solvents such as ethanol, chloroform, and dichloromethane, owing to compatibility with non-polar and moderately polar solvents.

Furthermore, factors influencing its solubility may include:

  • Temperature: Increasing temperature often enhances solubility in organic solvents by providing sufficient energy to overcome intermolecular forces.
  • Presence of surfactants: The addition of surfactants can significantly improve the solubility by forming micelles that allow for better dispersion in aqueous solutions.
  • Polarity of the solvent: Choosing the right solvent polarity is crucial as it directly impacts the solubility behavior.

In conclusion, while [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate shows limited aqueous solubility, opportunities for solubility enhancement through organic solvents and temperature adjustments exist, making it versatile in various applications.

Interesting facts

Interesting Facts about [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] Acetate

This compound is a fascinating member of the class of organic compounds known as steroids. Here are some intriguing points regarding this specific acetate derivative:

  • Steroidal Backbone: The compound features a complex steroid structure, characterized by its multiple fused ring system. This structure is significant in many biological functions, including hormonal regulation and cellular signaling.
  • Biological Relevance: Steroids like this compound often exhibit significant biological activities, influencing processes such as metabolism, immune function, and reproductive health. Understanding their mechanisms can lead to breakthroughs in pharmaceuticals.
  • Acetate Functionality: The presence of the acetate group enhances the compound's lipid solubility—facilitating its ability to cross cell membranes, thereby enhancing its potential bioactivity.
  • Chirality Matters: The stereochemistry defined by the (3S, 8R, 9S, 10R, 13S, 14S) configuration is crucial. These chiral centers result in specific spatial arrangements that can dramatically influence the compound's interactions with biological macromolecules.
  • Potential Applications: Research into such compounds can pave the way for new therapeutic agents, particularly in treating conditions like hormonal disorders or specific cancers where steroid hormones play a critical role.

Exploring the properties and reactions of this compound not only broadens our understanding of steroids but also inspires new avenues in chemical synthesis and drug discovery. As scientists continue to investigate such compounds, they unlock doors to innovative treatments and insights into human health.

Synonyms
3beta-acetoxyandrost-5-en-17-one
Dehydroepiandrosterone acetate
853-23-6
Dehydroisoandrosterone 3-acetate
Prasterone acetate
Dhea acetate
Dehydroisoandrosterone acetate
Dehydroepiandrosterone 3-acetate
trans-Dehydroandrosterone acetate
Androst-5-en-17-one, 3-(acetyloxy)-, (3b)-
3beta-Acetoxy-5-androstene-17-one
Dehydroisoandosterone 3-acetate
[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate
DTXSID3020380
45751H45MY
Androstenolone acetate
(3beta)-17-oxoandrost-5-en-3-yl acetate
DTXCID90380
CCRIS 7926
3-beta-Acetoxydehydroepiandrosterone
SKF 2847
EINECS 212-714-1
5-Androsten-3beta-ol-7-one acetate
17-Oxoandrost-5-en-3beta-yl acetate
delta5-Dehydroepiandrosterone 3-acetate
Dehydro Epiandrosterone 3-Acetate
Dehydroepiandrost-5-en-17-one 3-acetate
3beta-Hydroxy-5-androsten-17-one acetate
3beta-Hydroxyandrost-5-en-17-one acetate
3beta-Hydroxy-5-androstene-17-one acetate
3-beta-Hydroxyandrost-5-en-17-one acetate
3beta-Hydroxyandrost-5-en-17-one 3-acetate
UNII-45751H45MY
17-Oxoandrost-5-en-3-yl acetate #
prasterone-acetate
NCGC00016544-01
CAS-853-23-6
Androst-5-en-17-one, 3-(acetyloxy)-, (3-beta)-
Dehydroepiandrosterone 3-acetate;DHEA acetate
Prestwick0_000937
Prestwick1_000937
Prestwick2_000937
Prestwick3_000937
Androst-5-en-17-one, 3-beta-hydroxy-, acetate
BSPBio_000874
MLS002154068
SCHEMBL298142
SPBio_003043
BPBio1_000962
CHEMBL1480686
CHEBI:135410
3betaacetoxy-5-androstene-17-one
HMS1570L16
HMS2097L16
HMS2230I06
HMS3714L16
HY-B1405
3beta-acetoxy-androst-5-en-17-one
Tox21_110485
Tox21_200963
s5508
3-(Acetyloxy)androst-5-ene-17-one
3beta-acetoxy-5-androstene -17-one
AKOS015895423
CCG-220937
CS-6082
Dehydroisoandrosterone 3-acetate, 97%
FD12035
NCGC00179388-01
NCGC00179388-02
NCGC00258516-01
AS-20015
SMR001233383
5-Androsten-3.beta.-ol-17-one, 3-acetate
AB00171449
D0045
NS00038884
BRD-K96527333-001-03-4
Q27258813
Acetic acid (3S,8R,10R,13S)-10,13-dimethyl-17-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester