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Oxymetazoline Hydrochloride

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Identification
Molecular formula
C23H31Cl2N3O
CAS number
2313-23-3
IUPAC name
(3S,9S,14S,17S)-17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;dihydrochloride
State
State

At room temperature, this compound is typically a solid.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
337.26g/mol
Molar mass
337.2630g/mol
Density
1.2100g/cm3
Appearence

The compound is typically found as a crystalline solid. In its pure form, it is white to off-white. It is often formulated in a solution for commercial use.

Comment on solubility

Solubility Profile

The solubility of the compound (3S,9S,14S,17S)-17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; dihydrochloride can be influenced by various factors due to its complex structure. While specific solubility data may vary, several key aspects can be highlighted:

  • Water Solubility: As a dihydrochloride salt, this compound generally exhibits improved solubility in water compared to its base form, owing to the ionizable nature of the hydrochloride groups.
  • Polarity Considerations: The presence of multiple functional groups such as amine (-NH) and hydroxyl (-OH) indicates potential for hydrogen bonding, which can enhance solubility in polar solvents.
  • Organic Solvents: Additionally, due to its large hydrophobic hydrocarbon backbone, the compound may demonstrate variable solubility in non-polar organic solvents. Common solvents to test include ethanol, methanol, and dimethyl sulfoxide (DMSO).

In general, it is often useful to perform solubility tests under various conditions to obtain a comprehensive understanding of the compound's behavior in different media. As is often stated, "Solubility is the gateway to bioavailability", making it a critical aspect in the study of pharmacological compounds.

Interesting facts

Interesting Facts about (3S,9S,14S,17S)-17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; dihydrochloride

This compound presents a fascinating example of synthetic chemistry, illustrating the intricate relationships between molecular structure and biological activity. Commonly recognized in pharmacology, it has a well-characterized mechanism of action that contributes to its therapeutic effects.

Key Characteristics

  • Structure Complexity: The compound features a complex tetracyclic structure that contributes to its unique properties and biological function.
  • Dimethylamino Group: The presence of the dimethylamino group significantly influences its pharmacological properties, enhancing solubility and receptor binding capabilities.
  • Therapeutic Applications: This compound is closely associated with treatments for various conditions, showcasing significant efficacy in the treatment of hormonal imbalances.
  • Chiral Centers: With multiple chiral centers, the molecule exhibits stereoisomerism, which can profoundly affect how it interacts with biological systems.

Moreover, the compound's modification led to improvements in selectivity and efficacy, making it a subject of interest for researchers focused on drug development. As pharmaceutical scientists often quote, “Structure governs function,” and this principle rings particularly true for this compound. Its intricate design allows for targeted action within complex physiological pathways, while also posing interesting challenges for synthesis and characterization in the lab.

In conclusion, the study of such compounds not only enhances our understanding of molecular interactions but also opens avenues for innovative treatment strategies in modern medicine. The ongoing exploration in this field is vital for advancing pharmaceutical sciences.