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Alfatradiol

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Identification
Molecular formula
C19H30O
CAS number
57-91-0
IUPAC name
(3S,9S,14S,17S)-17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
State
State

At room temperature, Alfatradiol is typically a solid in its pure form. However, it is commonly supplied in liquid solutions for practical applications. In solid form, it is a white crystalline powder.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
293.45g/mol
Molar mass
293.4510g/mol
Density
1.0205g/cm3
Appearence

Alfatradiol appears as a white crystalline solid. It is commonly used in solutions, where it retains a clinical and clean appearance.

Comment on solubility

Solubility Characteristics

The compound with the complex name (3S,9S,14S,17S)-17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol presents intriguing solubility properties that are quite important for its applications.

General Solubility Behavior

This molecule is characterized by its organic structure, and solubility may vary based on the following factors:

  • Polarity: The presence of the dimethylamino group suggests that this compound could exhibit some degree of polarity. This may enhance solubility in polar solvents such as water, but it may be less soluble in non-polar solvents.
  • Hydrophobic Characteristics: The extensive hydrocarbon portion of the molecule contributes to non-polar characteristics, which could limit solubility in aqueous environments.
  • Functional Groups: Functional groups like alcohols or amines usually increase solubility in polar solvents through hydrogen bonding mechanisms.

Expected Solubility

Based on the structural components, one might expect:

  • Partially soluble in water: Due to the amine functional group.
  • Soluble in aprotic solvents: Such as dimethyl sulfoxide (DMSO) or dimethylformamide (DMF).
  • Limited solubility in non-polar solvents: Such as hexane or benzene.

In conclusion, while the exact solubility needs specific experimental validation, the interactions based on the functional groups and structural features provide a compelling basis for predicting the solubility behavior of this fascinating compound.

Interesting facts

Interesting Facts about (3S,9S,14S,17S)-17-[3-(dimethylamino)propyl-methyl-amino]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

This complex organic compound belongs to a class of chemicals known for their intricate structures and important biological activities. Here are some engaging insights:

  • Structural Complexity: The compound features multiple chiral centers, which contributes to its stereochemical diversity. The specific arrangement of these atoms allows for different three-dimensional shapes, or stereoisomers, significantly influencing its biological action.
  • Focus on Nitrogen: With its dimethylamino and methylamino groups, the compound is rich in nitrogen, which is often linked to its pharmacological properties. Nitrogen-containing compounds are commonly seen in drug design due to their ability to interact with various biological targets.
  • Applications in Medicine: Compounds similar to this one are often investigated for their potential therapeutic effects. They may exhibit properties that can modulate hormone levels or have influence over neurological pathways, making them valuable in the development of treatments for various conditions.
  • Historical Context: Compounds like this have been studied in the context of steroidal frameworks. Research into steroids has historically revolutionized our understanding of hormones and how they affect human physiology.
  • Analytical Techniques: The study of such compounds often necessitates the use of advanced analytical techniques, including mass spectrometry and NMR spectroscopy, to elucidate their structure and confirm their purity.

In conclusion, the intricate nature of this compound exemplifies the beauty of organic chemistry, where small changes in molecular architecture can lead to significant variations in chemical behavior and biological activity. The ongoing research into its potential applications continues to highlight the relevance of such compounds in scientific inquiry.