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Alpidem

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Identification
Molecular formula
C21H23N3O3
CAS number
82626-30-2
IUPAC name
4-[1-(3-oxo-3-phenyl-propyl)pyrrolidin-3-yl]-1,4-benzoxazin-3-one
State
State

At room temperature, Alpidem is a solid, exhibiting a stable crystalline form that makes it relatively easy to handle in laboratory and industrial settings.

Melting point (Celsius)
124.00
Melting point (Kelvin)
397.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
391.46g/mol
Molar mass
391.4590g/mol
Density
1.2713g/cm3
Appearence

Alpidem is typically a crystalline solid and can appear as a white to off-white powder, depending on the specific formulation. It is not particularly soluble in water and has a characteristic molecular structure involving a benzoxazinone core, enhancing its solid-state stability.

Comment on solubility

Solubility of 4-[1-(3-oxo-3-phenyl-propyl)pyrrolidin-3-yl]-1,4-benzoxazin-3-one

The solubility of the compound 4-[1-(3-oxo-3-phenyl-propyl)pyrrolidin-3-yl]-1,4-benzoxazin-3-one can be influenced by various factors, given its complex molecular structure. Understanding its solubility is crucial for applications in pharmaceuticals and other chemical processes.

Key Considerations for Solubility:

  • Polarity: The presence of aromatic rings and functional groups like the carbonyl (C=O) may affect the polarity of the molecule, contributing to its solubility in certain solvents.
  • Temperature: Generally, solubility increases with temperature for many solid compounds. For this specific compound, assessing its solubility at varying temperatures can determine its practical use.
  • Solvent Type: This compound may exhibit variable solubility in polar solvents (such as water) versus non-polar solvents (like hexane). Testing in different solvents is essential to ascertain the best conditions for dissolution.
  • pH Sensitivity: If the compound contains ionizable groups, its solubility might change with the pH of the solution, thus impacting its utilization in biological systems.

In conclusion, while the solubility of 4-[1-(3-oxo-3-phenyl-propyl)pyrrolidin-3-yl]-1,4-benzoxazin-3-one is not straightforwardly predictable, analyzing its solvent compatibility and respective solubilization behavior can yield valuable insights for its applications. Further empirical studies are warranted to establish a detailed solubility profile.

Interesting facts

Interesting Facts about 4-[1-(3-oxo-3-phenyl-propyl)pyrrolidin-3-yl]-1,4-benzoxazin-3-one

This intriguing compound, embedded in the field of organic chemistry, showcases a combination of functional groups that contribute to its potential applications in various domains, including pharmaceuticals and agriculture.

Unique Structural Features

  • Pyrrolidine Ring: The presence of the pyrrolidine ring adds notable *cyclic properties*, which may influence the compound's reactivity and biological interactions. This five-membered ring often formulates the backbone for many alkaloids.
  • Benzoxazinone Moiety: The benzoxazinone portion serves as a *bioactive scaffold*, known for its diverse biological activities, including antibacterial and anticancer properties.
  • Carbonyl Group: The inclusion of the carbonyl group from the 3-oxo-3-phenyl propyl unit enhances the compound’s potential to form hydrogen bonds, thus contributing to its biological efficacy.

Potential Applications

The versatility of this compound opens doors to numerous applications:

  • Medicinal Chemistry: It may serve as a lead compound in drug discovery, particularly within the realms of neuropharmacology and anti-inflammatory therapies.
  • Agricultural Chemistry: Compounds with similar structures have been investigated for their potential as pesticides or herbicides, owing to their biological activity against unwanted organisms.

Future Research Directions

As a compound of interest, researchers are exploring:

  • Its *mechanism of action* within biological systems, aiming to unveil the pathways through which it exhibits activity.
  • The synthesis of derivatives to enhance properties like *solubility*, *selectivity*, and *potency*, ultimately broadening its scope in therapeutic applications.

In conclusion, 4-[1-(3-oxo-3-phenyl-propyl)pyrrolidin-3-yl]-1,4-benzoxazin-3-one is a noteworthy compound that, through its unique structure and potential applications, continues to inspire curiosity and investigation within the scientific community.