Skip to main content

4-[1-(3-phenylisoxazol-5-yl)ethyl]morpholine

ADVERTISEMENT
Identification
Molecular formula
C15H18N2O2
CAS number
106261-48-7
IUPAC name
4-[1-(3-phenylisoxazol-5-yl)ethyl]morpholine
State
State
The compound is typically a solid at room temperature.
Melting point (Celsius)
158.50
Melting point (Kelvin)
431.65
Boiling point (Celsius)
485.20
Boiling point (Kelvin)
758.35
General information
Molecular weight
272.33g/mol
Molar mass
272.3310g/mol
Density
1.2400g/cm3
Appearence

The compound typically appears as a crystalline solid, which might range from white to off-white or light yellow, depending on its purity and form.

Comment on solubility

Solubility of 4-[1-(3-phenylisoxazol-5-yl)ethyl]morpholine

4-[1-(3-phenylisoxazol-5-yl)ethyl]morpholine is a compound that exhibits varying solubility characteristics which are influenced by several factors:

  • Polarity: The presence of both morpholine and isoxazole groups contributes to different polar characteristics, often leading to moderate solubility in polar solvents.
  • Solvent Choice: This compound is likely to soluble in polar organic solvents like ethanol or methanol due to its structure.
  • Hydrophilicity vs. Hydrophobicity: The phenyl group adds hydrophobic characteristics, which might limit solubility in highly polar solvents.
  • Temperature Influence: As with many organic compounds, increasing the temperature can enhance solubility, thus it’s advisable to consider heating when dissolving this compound.

In summary, when working with 4-[1-(3-phenylisoxazol-5-yl)ethyl]morpholine, it's crucial to consider both the solvent's polarity and the compound's structural features to achieve optimal solubility. Additionally, performing solubility tests in various solvents can provide more accurate insights into its behavior in specific applications.

Interesting facts

Interesting Facts About 4-[1-(3-phenylisoxazol-5-yl)ethyl]morpholine

This compound, with its complex structure, is an intriguing member of the morpholine family known for its diverse applications in pharmaceutical science. Here are some fascinating aspects:

  • Pharmaceutical Relevance: Compounds like 4-[1-(3-phenylisoxazol-5-yl)ethyl]morpholine are frequently researched for their potential therapeutic effects. Its derivatives have been explored in the treatment of various diseases, including certain cancers and neurological disorders.
  • Structure-Activity Relationship (SAR): The presence of the isoxazole ring enhances the bioactivity of the molecule, making it a subject of interest in medicinal chemistry. The interaction between the morpholine and the isoxazole groups is critical for the compound’s pharmacological activity.
  • Tuning Properties: Scientists can modify this compound to create analogues that could exhibit improved efficacy, reduced toxicity, or better bioavailability. Fine-tuning such structures often leads to breakthroughs in drug development.
  • Role of the Phenyl Ring: The phenyl group attached to the isoxazole contributes to the lipophilicity of the molecule, which is essential for crossing biological membranes. This aspect plays a crucial role in drug design, affecting how the compound interacts with cellular targets.

In summary, the study of 4-[1-(3-phenylisoxazol-5-yl)ethyl]morpholine represents a compelling intersection of chemistry and medicine, showcasing how intricate molecular structures can lead to groundbreaking therapeutic advancements. As researchers continue to explore its potential, the value of understanding both its chemical makeup and biological implications cannot be overstated.