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Methamphetamine

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Identification
Molecular formula
C10H15N
CAS number
537-46-2
IUPAC name
4-(1-amino-1-methyl-ethyl)-1-methyl-cyclohexanamine
State
State

At room temperature, methamphetamine can be found as a solid when in the form of its crystalline hydrochloride salt, or as a liquid in its freebase form.

Melting point (Celsius)
3.20
Melting point (Kelvin)
276.35
Boiling point (Celsius)
212.00
Boiling point (Kelvin)
485.15
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
0.8190g/cm3
Appearence

Methamphetamine is typically found as a colorless liquid in its freebase form, while in its crystalline hydrochloride form, it appears as translucent crystals that are similar in appearance to shards of glass or rock salt.

Comment on solubility

Solubility of 4-(1-amino-1-methyl-ethyl)-1-methyl-cyclohexanamine

The solubility of 4-(1-amino-1-methyl-ethyl)-1-methyl-cyclohexanamine can be characterized by its interaction with different solvents. Key factors influencing the solubility of this compound include:

  • Polarity: The presence of amino groups typically enhances the solubility in polar solvents such as water.
  • Hydrogen Bonding: This compound can engage in hydrogen bonding, which often leads to improved solubility in aqueous solutions.
  • Temperature: As with many organic compounds, increasing temperature generally increases solubility.
  • pH Levels: The solubility may vary in different pH environments, particularly due to the behavior of the amino group under varying pH conditions.

It's important to note that while this compound may show a degree of solubility in water, the extent may not be high due to its organic structure. As noted, "the solubility of a compound is one of the most important characteristics that determines its behavior in biological systems." Therefore, understanding the solubility can be critical for applications in pharmacology and organic chemistry.

Interesting facts

Interesting Facts about 4-(1-amino-1-methyl-ethyl)-1-methyl-cyclohexanamine

4-(1-amino-1-methyl-ethyl)-1-methyl-cyclohexanamine, often referred to in the context of research and application, is a fascinating compound within the realm of organic chemistry. Here are several noteworthy aspects of this compound:

  • Structural Significance: The unique structure of this molecule incorporates a cyclohexane ring, which is known for its robustness and is often a fundamental building block in organic synthesis.
  • Functional Groups: This compound features both amino and methyl groups, which can significantly influence its chemical reactivity and interactions in biological systems.
  • Biological Relevance: Compounds with similar structures have been studied for their potential effects in drug formulation and biological activity, making it a compound of interest in medicinal chemistry.
  • Research Applications: As researchers explore its properties, this compound may serve as a model for developing new pharmaceuticals that target specific biological pathways.
  • Analytical Techniques: Characterizing this compound often employs advanced analytical methods such as NMR spectroscopy and mass spectrometry, providing insights into its structure and purity.

As noted by chemists, "Understanding the structural nuances of compounds like 4-(1-amino-1-methyl-ethyl)-1-methyl-cyclohexanamine is crucial for the advancement of synthetic methodologies and pharmaceutical developments." Studying the interplay of chemical properties and potential applications makes this compound a valuable subject of exploration.

In summary, 4-(1-amino-1-methyl-ethyl)-1-methyl-cyclohexanamine is more than just a chemical entity; it represents a gateway to understanding complex biochemical interactions and the development of innovative materials in science.

Synonyms
1,8-Diamino-p-menthane
80-52-4
4-(2-aminopropan-2-yl)-1-methylcyclohexanamine
Menthanediamine
P-MENTHANE-1,8-DIAMINE
1,8-p-Menthanediamine
1,8-Menthanediamine
Menthane diamine
4-(2-aminopropan-2-yl)-1-methylcyclohexan-1-amine
54166-24-4
USAF RH-4
p-Menthane-1,8-diyldiamine
CCRIS 4836
NSC 5612
EINECS 201-287-7
Cis-1,8-diamino-p-methane
UNII-S583DR301G
BRN 1098767
DTXSID3021772
AI3-23799
Cyclohexanemethanamine, 4-amino-alpha,alpha,4-trimethyl-
NSC-5612
Cyclohexanemethanamine, 4-amino-.alpha.,.alpha.,4-trimethyl-
DTXCID401772
S583DR301G
4-13-00-00023 (Beilstein Handbook Reference)
MENTHANE-1,8-DIAMINE, P-
J36.813J
4-(1-Amino-1-methylethyl)-1-methylcyclohexanamine
4-Amino-.alpha.,.alpha.,4-trimethylcyclohexanemethamine
Primene MD
cis-1,8-Diamino-p-menthane
NSC5612
KIER-C3
SCHEMBL242895
SCHEMBL2520233
SCHEMBL2520236
P-METHANE-1,8-DIAMINE
CHEMBL1533517
SCHEMBL11508804
KOGSPLLRMRSADR-CZMCAQCFSA-N
DTXSID601224807
Tox21_201132
BBL027343
cis-1,8-Diamino-p-menthane, 98%
STK802050
WLN: L6TJ AZ A1 DXZ1&1
AKOS015894767
AKOS015955259
CAS-80-52-4
NCGC00091682-01
NCGC00091682-02
NCGC00258684-01
VS-08528
Cyclohexanemethanamine,.alpha.,4-trimethyl-
CS-0326370
CS-0433554
NS00020707
4-Amino-alpha,alpha,4-trimethylcyclohexanemethamine
cis-4-(2-Aminopropan-2-yl)-1-methylcyclohexanamine
4-(1-Amino-1-methylethyl)-1-methylcyclohexanamine #
Q27288645
cis-4-(2-Aminopropan-2-yl)-1-methylcyclohexan-1-amine
(1r,4r)-4-(2-aminopropan-2-yl)-1-methylcyclohexanamine
1-AMINO-1-METHYL-4-(2-AMINO-2-PROPYL)CYCLOHEXANE
1-METHYL-4-(1-AMINO-1-METHYLETHYL)CYCLOHEXYLAMINE
trans-4-Amino-I+/-,I+/-,4-trimethylcyclohexanemethanamine
4-AMINO-ALPHA,ALPHA,4-TRIMETHYL-CYCLOHEXANE METHAMINE
54166-25-5