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4'-Fluorococaine

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Identification
Molecular formula
C19H26FNO
CAS number
849231-88-9
IUPAC name
4-(1-azaspiro[4.5]decan-1-yl)-1-(4-fluorophenyl)butan-1-one
State
State

At room temperature, this compound is typically found in a solid state. Its distinct crystalline appearance is due to the molecular interactions within its structural framework, particularly its spirocyclic and phenyl components.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
362.00
Boiling point (Kelvin)
635.15
General information
Molecular weight
331.43g/mol
Molar mass
331.4380g/mol
Density
1.1245g/cm3
Appearence

4-(1-azaspiro[4.5]decan-1-yl)-1-(4-fluorophenyl)butan-1-one typically appears as a crystalline powder. The compound may exhibit a slight off-white coloration depending on its purity and any present impurities. It has distinctive physical properties that align with its unique chemical structure, which includes a spirocyclic component contributing to its structural complexity.

Comment on solubility

Solubility of 4-(1-azaspiro[4.5]decan-1-yl)-1-(4-fluorophenyl)butan-1-one

The solubility of the compound 4-(1-azaspiro[4.5]decan-1-yl)-1-(4-fluorophenyl)butan-1-one is influenced by various factors, including its molecular structure and the presence of functional groups. Generally, the solubility characteristics can be summarized as follows:

  • Polarity: The presence of fluorine in the aromatic ring suggests moderate polarity, which may enhance solubility in polar solvents.
  • Hydrophobic Interactions: The spirocyclic structure tends to introduce hydrophobic characteristics, which may limit solubility in water.
  • Solvent Compatibility: This compound is likely to be more soluble in organic solvents such as dichloromethane or ethyl acetate rather than aqueous solutions.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature, making warm organic solvents more favorable.

As a result, it is essential to consider the solvent choice depending on the desired outcomes in research and applications. In summary, 4-(1-azaspiro[4.5]decan-1-yl)-1-(4-fluorophenyl)butan-1-one exhibits selective solubility primarily influenced by its molecular characteristics and the solvent environment.

Interesting facts

Interesting Facts about 4-(1-azaspiro[4.5]decan-1-yl)-1-(4-fluorophenyl)butan-1-one

This compound, known as a spirocyclic analogue, is notable for its complex structure which offers a fascinating array of chemical behavior and potential applications. Here are some key points regarding this intriguing molecule:

  • Structural Complexity: The inclusion of the spiro ring system in its architecture allows for unique conformational possibilities, which can influence its biological activity and interactions.
  • Pharmacological Interest: Compounds with spirocyclic structures are of great interest in medicinal chemistry, especially for their potential as drug candidates. They often exhibit enhanced selectivity and reduced side effects in pharmacological studies.
  • Fluorine Substitution: The presence of the fluorine atom in the phenyl group enhances the lipophilicity of the molecule, potentially leading to improved cell membrane permeability, a desirable feature in pharmaceutical design.
  • Dexterity in Synthesis: The synthetic pathways to produce such compounds involve intricate reactions and careful control of stereochemistry, showcasing the art and precision necessary in modern organic synthesis.
  • Research Implications: Ongoing research may reveal more about its interactions with biological targets, making it a valuable starting point for developing new therapeutics.

As we delve deeper into the world of spirocyclic compounds like 4-(1-azaspiro[4.5]decan-1-yl)-1-(4-fluorophenyl)butan-1-one, we uncover the hidden potential these unique structures hold in advancing both chemistry and medicine. Each discovery adds to our understanding of how molecular structure translates into function, ultimately contributing to the innovation of new treatments and technologies.

Synonyms
1093-11-4
BRN 1430818
4-(1-Azaspiro(4.5)dec-1-yl)-4'-fluoro-butyrophenone
DTXSID50911091
BUTYROPHENONE, 4-(1-AZASPIRO(4.5)DEC-1-YL)-4'-FLUORO-
4-(1-azaspiro[4.5]decan-1-yl)-1-(4-fluorophenyl)butan-1-one