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Salbutamol

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Identification
Molecular formula
C13H21NO3·CH4O3S
CAS number
18559-94-9
IUPAC name
4-[1-hydroxy-2-(isopropylamino)butyl]benzene-1,2-diol;methanesulfonic acid
State
State

Salbutamol is typically found in a solid state at room temperature, appearing as a white crystalline powder. When combined with methanesulfonic acid, it is usually processed into tablets or inhalable forms for medical use.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
306.40g/mol
Molar mass
239.3110g/mol
Density
1.2590g/cm3
Appearence

Salbutamol appears as a white or almost white crystalline powder. It is often found in a finely divided form when used in medicinal formulations.

Comment on solubility

Solubility of 4-[1-hydroxy-2-(isopropylamino)butyl]benzene-1,2-diol; methanesulfonic acid

The solubility of the compound 4-[1-hydroxy-2-(isopropylamino)butyl]benzene-1,2-diol in combination with methanesulfonic acid is influenced by various factors. Understanding these factors can help predict how the compound behaves in different environments.

  • Polarity: The presence of multiple hydroxyl groups in the formula contributes significantly to its polar nature, which often increases solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents plays a crucial role. Hydroxyl groups can interact with water molecules, enhancing solubility.
  • pH Levels: The acidity of methanesulfonic acid may aid in the solubility of this compound when dissolved in aqueous solutions, affecting the ionization state of the amino group.
  • Temperature: Generally, an increase in temperature can enhance solubility; thus, this factor should be considered during experimentation.

In summary, the solubility of the compound incorporates not just its chemical structure but also environmental conditions. As one researcher noted, "A compound's solubility is often a dance of molecular interactions," highlighting the complex interplay at work.


Overall, when evaluating the solubility of this compound, it is pivotal to conduct empirical tests and consider comprehensive solvent interactions to make accurate predictions on its behavior in diverse settings.

Interesting facts

Interesting Facts about 4-[1-Hydroxy-2-(isopropylamino)butyl]benzene-1,2-diol; Methanesulfonic Acid

This compound is a fascinating example of an organic molecule that merges functional groups with therapeutic applications. Here are some insightful points about it:

  • Dual Functionality: The compound features both a phenolic structure and an isopropylamino group, which opens up multiple pathways for chemical reactivity and biological interaction.
  • Medicinal Potential: Compounds that contain structural motifs similar to this one often exhibit pharmacological properties, making them of interest in medicinal chemistry.
  • Solubility Properties: The presence of the methanesulfonic acid group suggests that this compound may have enhanced solubility in biological systems, which is crucial for drug development and delivery.
  • Research Applications: This compound could potentially serve as a lead compound in drug synthesis or be utilized in the development of biochemical assays to study receptor interactions.

Research into compounds like this one can lead to significant advancements in various fields, including pharmaceutical sciences and biochemistry. Understanding its properties and mechanisms of action could contribute to novel therapeutic solutions in treating various diseases.

As we explore compounds such as 4-[1-hydroxy-2-(isopropylamino)butyl]benzene-1,2-diol; methanesulfonic acid, we are reminded that even small changes in molecular structure can lead to vastly different properties and applications. This is a testament to the underlying complexity of organic chemistry!

Synonyms
ISOETHARINE MESYLATE
7279-75-6
isoetharine mesilate
DTXSID2045571
NSC-759286
DTXCID0025571
ISOETARINE MESILATE (MART.)
ISOETHARINE MESYLATE (USP IMPURITY)
Mesylate, Isoetharine
4-(1-HYDROXY-2-(ISOPROPYLAMINO)BUTYL)BENZENE-1,2-DIOL METHANESULFONATE (SALT)
1,2-BENZENEDIOL, 4-(1-HYDROXY-2-((1-METHYLETHYL)AMINO)-BUTYL)-, METHANESULPHONATE (SALT)
3,4-DIHYDROXY-alpha-(1-(ISOPROPYLAMINO)PROPYL)BENZYL ALCOHOL METHANESULPHONATE (SALT)
230-695-8
Isoetharine mesylate salt
Isotharine mesylate
Isoetharine (mesylate)
4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE
Isoetarine mesilate
MLS000069674
Isoetarine mesilate; Isoetharine mesylate
SMR000058457
4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol;methanesulfonic acid
Isoetharine mesylate (USP)
SR-01000000183
Bronkometer (TN)
NCGC00017071-01
CAS-7279-75-6
Prestwick_1003
Opera_ID_1465
MLS001146940
SCHEMBL212005
REGID_for_CID_23702
CHEMBL1201153
SOYAGMVKMXZVNZ-UHFFFAOYSA-N
HMS1570E20
HMS2093J16
HMS2097E20
HMS2230F06
HMS3262G03
HMS3714E20
Pharmakon1600-01505977
HY-B1481
Tox21_110768
Tox21_500671
MFCD00133422
NSC759286
4-[1-Hydroxy-2-[(1-methylethyl)amino]butyl]-1,2-benzenediol mesylate salt
AKOS015889242
CCG-213584
FI61557
LP00671
NCGC00016157-02
NCGC00094032-01
NCGC00261356-01
DA-60313
TS-09051
CS-0013181
EU-0100671
SW197083-3
D04626
G77951
I 3639
SR-01000000183-2
SR-01000000183-4
SR-01000000183-6
4-[1-Hydroxy-2-[(1-methylethyl)amino]butyl]-1,2-benzenediol mesylate