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Norepinephrine

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Identification
Molecular formula
C8H11NO3
CAS number
51-41-2
IUPAC name
4-[1-hydroxy-2-(isopropylamino)ethyl]phenol
State
State

Norepinephrine is typically in a solid state at room temperature. It is often used in its hydrochloride salt form, which is also a solid at room conditions, making it easier to handle and dissolve in aqueous solutions for medical use.

Melting point (Celsius)
217.00
Melting point (Kelvin)
490.15
Boiling point (Celsius)
386.80
Boiling point (Kelvin)
659.95
General information
Molecular weight
169.20g/mol
Molar mass
169.2040g/mol
Density
1.0890g/cm3
Appearence

Norepinephrine appears as a light beige to slightly brownish crystalline powder when pure. It is typically handled in its hydrochloride salt form for various applications, which has a more consistent white appearance.

Comment on solubility

Solubility of 4-[1-hydroxy-2-(isopropylamino)ethyl]phenol

The compound 4-[1-hydroxy-2-(isopropylamino)ethyl]phenol presents intriguing solubility characteristics. Understanding its solubility can help not only in its applications but also in its interactions in various solvents.

Key Points of Solubility:

  • Polar Solvents: This compound is likely to be soluble in polar solvents due to the presence of the hydroxyl group (-OH), which can engage in hydrogen bonding.
  • Non-Polar Solvents: On the contrary, solubility in non-polar solvents may be limited, as the hydrophobic isopropylamino group can create some resistance to this type of solvation.
  • Temperature Dependence: The solubility can be temperature-dependent; generally, increased temperature can enhance solubility in various solvents.
  • Concentration Effects: The solubility can also be affected by the concentration of the compound in the solvent, where higher concentrations may lead to precipitation.

In conclusion, while 4-[1-hydroxy-2-(isopropylamino)ethyl]phenol exhibits favorable solubility in polar environments, its performance may be less effective in non-polar conditions. This delicate balance can be crucial for applications involving this compound.

Interesting facts

Interesting Facts About 4-[1-Hydroxy-2-(isopropylamino)ethyl]phenol

This compound, often referred to in the research community for its unique properties, serves as a significant subject within the field of pharmaceutical chemistry. Here are some key points about it:

  • Pharmaceutical Relevance: This compound is known for its role in various medicinal formulations. It exhibits properties that can influence physiological responses, making it a compound of interest in drug design.
  • Mechanism of Action: The presence of the isopropylamino group suggests potential interactions with neurotransmitter systems, which researchers are exploring for therapeutic applications in mood disorders.
  • Analytical Studies: Due to its structural characteristics, this compound provides a fascinating subject for analytical chemistry. Scientists often study its behavior under different conditions to understand stability and reactivity.
  • Structure-Activity Relationship: The structural modifications of this compound serve as a basis for examining how chemical changes can influence biological activity, an essential aspect of medicinal chemistry.
  • Potential Applications: While further research is necessary, preliminary studies have hinted at its applications in enhancing the efficacy of existing pharmaceuticals, emphasizing the compound's potential in developing next-generation therapies.

In summary, 4-[1-hydroxy-2-(isopropylamino)ethyl]phenol stands out in the realm of chemical compounds for its diverse implications in health and medicine. As researchers continue to unveil its properties, this compound reveals itself as a promising candidate for future pharmaceutical innovations.

Synonyms
Deterenol
7376-66-1
Paraproterenol
dl-N-Isopropyloctopamine
Deterenol [INN]
4-(1-Hydroxy-2-(isopropylamino)ethyl)phenol
4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenol
Isopropylnorsynephrine
PI-39
BR971OUC9M
Deterenolum
1-(4-hydroxyphenyl)-2-isopropylaminoethanol
4-[1-HYDROXY-2-(ISOPROPYLAMINO)ETHYL]PHENOL
DETERNOLUM
WIN 833
UNII-BR971OUC9M
BRN 2098796
benzene, 1-hydroxy-4-(1-hydroxy-2-isopropylamino)ethyl-
PI 39
4-Hydroxy-alpha-isopropylaminomethylbenzyl alcohol
3506-31-8
4-13-00-02660 (Beilstein Handbook Reference)
SCHEMBL828537
(+-)-1-(4-Hydroxyphenyl)-2-(isopropylamino)ethanol
CHEMBL109378
BDBM92680
BENZYL ALCOHOL, p-HYDROXY-alpha-ISOPROPYLAMINOMETHYL-
DTXSID90956502
ISOPROTERENOL IMPURITY 32
4-Hydroxy-alpha-(((1-methylethyl)amino)methyl)benzenemethanol
BCP30658
AKOS006271446
(+/-)-PI 39
G87664
Q27274837
4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol, 8
BENZYL ALCOHOL, P-HYDROXY-.ALPHA.-((ISOPROPYLAMINO)METHYL)-
(+/-)-P-HYDROXY-.ALPHA.-((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL
BENZENEMETHANOL, 4-HYDROXY-.ALPHA.-(((1-METHYLETHYL)AMINO)METHYL)-
BENZENEMETHANOL, 4-HYDROXY-.ALPHA.-(((1-METHYLETHYL)AMINO)METHY))-, (+/-)-
BENZYL ALCOHOL, P-HYDROXY-.ALPHA.-((ISOPROPYLAMINO)METHYL)-, HYDROCHLORIDE, (+/-)-
Deterenolum;DL-N-Isopropyloctopamine;4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol
RACTOPAMINE HYDROCHLORIDE IMPURITY N-ISOPROPYLOCTOPAMINE [USP IMPURITY]