Epinephrine | Solubility of Things

Identification

Molecular formula

C₉H₁₃NO₃

CAS number

51-43-4

IUPAC name

4-[1-hydroxy-2-(methylamino)ethyl]phenol

State

At room temperature, epinephrine is typically in a solid crystalline form.

Melting point (Celsius)

211.00

Melting point (Kelvin)

484.15

Boiling point (Celsius)

244.00

Boiling point (Kelvin)

517.15

General information

Molecular weight

183.20g/mol

Molar mass

183.2070g/mol

Density

1.2830g/cm³

Appearence

Epinephrine appears as colorless or white crystalline powder. It may gradually darken upon exposure to air and light, resulting in a brownish appearance due to oxidation.

Comment on solubility

Solubility Characteristics of 4-[1-Hydroxy-2-(methylamino)ethyl]phenol

The solubility of 4-[1-hydroxy-2-(methylamino)ethyl]phenol, also known as 4-hydroxyphenyl-2-methylaminoethanol, can be examined from various perspectives:

Polarity: This compound contains multiple functional groups, including a hydroxyl group (-OH) and an amine group (-NH), which can significantly influence its solubility in polar solvents.
Solvent Compatibility: As a result of its polar character, 4-[1-hydroxy-2-(methylamino)ethyl]phenol is likely to be soluble in water and other polar solvents.
Hydrogen Bonding: The presence of both the hydroxyl and amine groups promotes hydrogen bonding, enhancing its solubility in aqueous solutions.
Temperature Dependence: The solubility of this compound may change with temperature, generally increasing with rising temperature, typical of many organic compounds.
pH Influence: The solubility might also be affected by the pH of the solution, particularly due to the amine moiety, which can be protonated under acidic conditions.

In summary, the solubility of 4-[1-hydroxy-2-(methylamino)ethyl]phenol is likely enhanced by its polar functional groups, making it soluble in water and various polar solvents, with solubility influenced by factors such as temperature and pH.

Interesting facts

Interesting Facts about 4-[1-hydroxy-2-(methylamino)ethyl]phenol

4-[1-hydroxy-2-(methylamino)ethyl]phenol, often referred to as a specific type of phenolic compound, showcases intriguing properties and applications in various fields. Here are some captivating aspects:

Versatile Applications: This compound plays a crucial role in the synthesis of antioxidants, which are pivotal in preventing oxidative stress in biological systems. Its structure allows it to effectively scavenge free radicals.
Biological Significance: Compounds like 4-[1-hydroxy-2-(methylamino)ethyl]phenol are often studied for their potential medicinal properties, including their effectiveness in treating skin conditions.
Research Interest: The phenolic hydroxyl group in its structure can contribute to various chemical reactions, making it a subject of interest in organic chemistry research, especially concerning the development of new pharmaceuticals.
Environmental Relevance: Phenolic compounds are also studied for their environmental impact. Understanding their degradation and interaction with other substances aids in assessing ecological risks.
Historical Context: The exploration of phenolic compounds dates back over a century, and their extensive study has led to significant advancements in both organic chemistry and medicinal chemistry.

Overall, the compound 4-[1-hydroxy-2-(methylamino)ethyl]phenol exemplifies the fascinating interplay of chemistry and biology, illustrating how a single molecule can have far-reaching implications across various scientific domains. As researchers continue to delve into its properties, we can expect to uncover even more applications and insights that underscore the importance of such compounds in contemporary science.

Synonyms

Synephrine

Oxedrine

94-07-5

p-Synephrine

Parasympatol

Sympatol

Sympaethamine

(+/-)-Synephrine

Sympaethamin

Analeptin

Synephrin

Synthenate

Simpalon

Simpatol

Ethaphene

Sympathol

4-[1-Hydroxy-2-(methylamino)ethyl]phenol

DL-SYNEPHRINE

p-Oxedrine

4-(1-Hydroxy-2-(methylamino)ethyl)phenol

Parakorper [German]

Parakorper

Synefrin

Advantra z

p-Methylaminoethanolphenol

1-(4-Hydroxyphenyl)-2-methylaminoethanol

Oxedrine [INN:BAN]

p-Hydroxyphenylmethylaminoethanol

rac-Synephrine

CHEBI:29081

1-(4-Hydroxyphenyl)-N-methylethanolamine

(+-)-N-Methyloctopamine

(RS)-1-(4-Hydroxyphenyl)-2-(methylamino)ethanol

EINECS 202-300-9

UNII-PEG5DP7434

Oxedrine (BAN)

NSC 166285

NSC-166285

NSC-170956

DTXSID0030588

Methylaminomethyl(4-hydroxyphenyl)carbinol

beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol

S 38537-9

1-(4-Hydroxyphenyl)-2-(methylamino)ethanol

SYNEPHRINE [MI]

Benzenemethanol, 4-hydroxy-a-[(methylamino)methyl]-, (aR)-

OXEDRINE [MART.]

OXEDRINE [WHO-DD]

NSC 170956

4-Hydroxy-alpha-((methylamino)methyl)benzenemethanol

SYNEPHRINE [USP-RS]

(+/-)-OXEDRINE

(.+/-.)-N-Methyloctopamine

p-((Methylamino)ethanol)phenol

PEG5DP7434

OXEDRINE [USP IMPURITY]

1-(4-Hydroxyphenyl)-(2-methylamino)ethanol

DTXCID8010588

alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan [German]

alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan

p-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol

4-hydroxy-alpha-[(methylamino)methyl]benzenemethanol

NSC166285

S-38537-9

.beta.-Methylamino-.alpha.-(4-hydroxyphenyl)ethyl alcohol

Benzenemethanol, 4-hydroxy-.alpha.-[(methylamino)methyl]-

(+)-[(methylamino)methyl]-Benzenemethano

OXEDRINE (MART.)

WLN: QR DYQ1M1

Synefrin [Czech]

SYNEPHRINE (USP-RS)

((Methylamino)methyl)((4-hydroxyphenyl)carbinol)

p-Hydroxy-alpha-[(methylamino)methyl]benzyl alcohol

p-[(Methylamino)ethanol]phenol

4-Hydroxy-.alpha.-((methylamino)methyl)benzenemethanol

p-Hydroxy-.alpha.-[(methylamino)methyl]benzyl alcohol

OXEDRINE (USP IMPURITY)

Benzyl alcohol, p-hydroxy-.alpha.-[(methylamino)methyl]-

p-Hydroxyphenyl(methylamino)ethanol

MFCD00002370

(+)-((Methylamino)methyl)-benzenemethano

SMR000059111

SYNEPHERINE

1-(4-Hydroxyphenyl)-(N-methylethanol)amine

p-Hydroxy-a-((methylamino)methyl)benzyl alcohol

p-Hydroxy-a-[(methylamino)methyl]benzyl alcohol

4-Hydroxy-a-((methylamino)methyl)benzenemethanol

4-Hydroxy-a-[(methylamino)methyl]benzenemethanol

4-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol

[(Methylamino)methyl][(4-hydroxyphenyl)carbinol]

p-Hydroxy-I+--((methylamino)methyl)benzyl alcohol

p-Hydroxy-I+--[(methylamino)methyl]benzyl alcohol

SR-01000002983

4-Hydroxy-I+--((methylamino)methyl)benzenemethanol

4-Hydroxy-I+--[(methylamino)methyl]benzenemethanol

p-Hydroxy-.alpha.-[(methylamino)methyl]benzylalcohol

benzene, 1-hydroxy-4-(1-hydroxy-2-methylamino)ethyl-

Benzenemethanol, 4-hydroxy-alpha-((methylamino)methyl)-

-Synephrine

BENZENEMETHANOL, 4-HYDROXY-.ALPHA.-((METHYLAMINO)METHYL)-

(y)-Synephrine

CAS-94-07-5

NCGC00016351-01

Oxedrine, Sympatol

(?)-Synephrine

(+-)-synephrine

(+,-)-Synephrine

Synephrine (Oxedrine)

Synephrine (Standard)

( inverted exclamation markA)-Synephrine

Prestwick0_001088

Prestwick1_001088

Prestwick2_001088

Prestwick3_001088

(.+/-.)-Synephrine

SYNEPHRINE [INCI]

(+/-)-N-Methyloctopamine

Lopac0_001085

BSPBio_001136

MLS000069435

MLS001424216

CHEMBL33720

SCHEMBL146500

SPBio_003028

Synephrine, analytical standard

BPBio1_001250

HY-N0132R

(+/-)-Synephrine, >=98%

BENZYL ALCOHOL, p-HYDROXY-alpha-((METHYLAMINO)METHYL)-

HMS1571I18

HMS2052G09

HMS2098I18

HMS2233F20

HMS3263I12

HMS3264E11

HMS3369C13

HMS3394G09

HMS3656O09

HMS3715I18

HMS3884D15

Pharmakon1600-01506085

ALBB-025740

HY-N0132

Tox21_110390

Tox21_200962

Tox21_501085

( inverted question mark)-Synephrine

BBL015111

BDBM50102660

NSC170956

NSC759316

PDSP1_000167

PDSP2_000166

s2362

STK803113

AKOS004119915

AKOS016038542

Tox21_110390_1

CCG-101098

CCG-205162

DB09203

KS-5152

LP01085

NC00348

NSC-759316

SDCCGSBI-0051055.P003

NCGC00015924-03

NCGC00015924-04

NCGC00015924-05

NCGC00015924-06

NCGC00015924-08

NCGC00015924-09

NCGC00015924-12

NCGC00015924-13

NCGC00015924-25

NCGC00089788-02

NCGC00089788-03

NCGC00089788-04

NCGC00258515-01

NCGC00261770-01

1ST40086

4-(1-Hydroxy-2-methylamino-ethyl)phenol

BP-12742

FS157243

SBI-0051055.P002

AB00514040

CS-0007857

EU-0101085

NS00007649

S0232

SW197214-5

4-[1-Hydroxy-2-(methylamino)ethyl]phenol #

4-Hydroxy-a-(methylaminomethyl)benzyl alcohol

b-Methylamino-a-(4-hydroxyphenyl)ethyl alcohol

C04548

D07148

EN300-267997

S 0752

AB00384265_11

Q421351

SR-01000002983-3

SR-01000002983-7

SR-01000002983-8

BRD-A04327189-001-14-4

BRD-A04327189-001-15-1

BRD-A04327189-001-16-9

BRD-A04327189-003-02-5

BRD-A04327189-003-03-3

7336264B-EDC9-42C5-939B-FF800AB5BB4A

202-300-9

4-Hydroxy-a-[(methylamino)methyl]benzenemethanol;Parasympatol;DL-Synephrine;(+/-)-N-Methyloctopamine

benzenemethanol, 4-hydroxy-alpha-[(methylamino)methyl]-, 2,3-dihydroxybutanedioate (1:1) (salt)