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Dopamine

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Identification
Molecular formula
C8H11NO2
CAS number
51-61-6
IUPAC name
4-[1-hydroxy-2-(methylamino)propyl]phenol
State
State
Dopamine is generally found as a solid white powder at room temperature.
Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
327.20
Boiling point (Kelvin)
600.40
General information
Molecular weight
153.18g/mol
Molar mass
153.1810g/mol
Density
1.2600g/cm3
Appearence

Dopamine is typically isolated as a white to off-white crystalline powder, although it can also appear as a colorless to pale yellow liquid when dissolved.

Comment on solubility

Solubility of 4-[1-hydroxy-2-(methylamino)propyl]phenol

The solubility of 4-[1-hydroxy-2-(methylamino)propyl]phenol can be influenced by several factors, making it a fascinating compound to explore in terms of its aqueous and organic solubility. Here are some key points to consider:

  • Polar Nature: This compound contains both hydroxyl (–OH) and amino (–NH2) functional groups, which increase its polarity and facilitate hydrogen bonding with water molecules.
  • Aqueous Solubility: Due to its polar characteristics, 4-[1-hydroxy-2-(methylamino)propyl]phenol is generally expected to have good solubility in water, especially at elevated temperatures.
  • Solvent Preference: While it is likely soluble in water, it may also dissolve well in organic solvents such as methanol and ethanol, where the interactions are favorable.
  • Temperature Effects: As with many organic compounds, solubility can increase with temperature, suggesting that heating may enhance its dissolution rate.

In conclusion, the solubility of 4-[1-hydroxy-2-(methylamino)propyl]phenol reflects the complex interplay between its chemical structure and environmental conditions. Understanding these nuances is crucial for applications in areas such as pharmaceuticals, where solubility can significantly impact bioavailability and efficacy.

Interesting facts

Interesting Facts about 4-[1-hydroxy-2-(methylamino)propyl]phenol

4-[1-hydroxy-2-(methylamino)propyl]phenol, commonly known in scientific contexts and sometimes referred to as a derivative of catecholamine, is a fascinating compound with notable properties. Here are some engaging insights:

  • Structural Significance: This compound features a phenolic structure, which is crucial for its biological activity. The presence of both a hydroxyl group and a methylamino group makes it unique in its functional applications.
  • Biological Role: It acts as a precursor to neurotransmitters, playing an essential role in the synthesis of catecholamines like dopamine and norepinephrine, which are vital for numerous physiological functions.
  • Therapeutic Potential: Due to its structural similarity to naturally occurring neurotransmitters, it’s investigated for its potential role in treating conditions related to imbalances in these neurotransmitters, such as depression and anxiety.
  • Chemical Versatility: This compound can serve as a building block in synthetic organic chemistry, offering pathways to develop various medicinal compounds.
  • Research Applications: Scientists study compounds like 4-[1-hydroxy-2-(methylamino)propyl]phenol for their potential neuroprotective effects, making it relevant in research pertaining to neurodegenerative diseases.

In the words of a notable chemist, "Understanding the structure-activity relationship of compounds like this opens doors to innovative therapeutic strategies." Thus, 4-[1-hydroxy-2-(methylamino)propyl]phenol remains a focus of research with promising implications in both biochemistry and pharmaceuticals.

Synonyms
Suprifen
4-[1-Hydroxy-2-(methylamino)propyl]phenol
52671-39-3
Oxilofrin
365-26-4
Carnigen
Benzenemethanol, 4-hydroxy-alpha-(1-(methylamino)ethyl)-
(R*,S*)-4-hydroxy-alpha-[1-(methylamino)ethyl]benzyl alcohol
NCGC00181090-01
DTXSID30110025
Benzenemethanol, 4-hydroxy-alpha-[1-(methylamino)ethyl]-
CHEMBL30400
SCHEMBL147458
AKOS006242956
NS00008305
4-[1-Hydroxy-2-(methylamino)propyl]phenol #
4-[(2R)-1-hydroxy-2-(methylamino)propyl]phenol
Q1689157
Benzyl alcohol, p-hydroxy-.alpha.-(1-(methylamino)ethyl)-
(.+/-.)-4-Hydroxy-alpha-(1-(methylamino)ethyl)benzyl alcohol
Benzenemethanol, 4-hydroxy-.alpha.-[1-(methylamino)ethyl]-, (R*,S*)-