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Fosfomycin

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Identification
Molecular formula
C4H11O3PS
CAS number
23155-02-4
IUPAC name
4-[1-[hydroxy(phenoxy)phosphoryl]pentylamino]-4-oxo-butanoic acid
State
State

Fosfomycin is generally found in a solid state at room temperature. It is marketed both as a powder and in crystalline form, which contributes to its ease of storage and use in pharmaceutical formulations.

Melting point (Celsius)
93.00
Melting point (Kelvin)
366.15
Boiling point (Celsius)
158.00
Boiling point (Kelvin)
431.15
General information
Molecular weight
138.06g/mol
Molar mass
138.0590g/mol
Density
1.3130g/cm3
Appearence

Fosfomycin typically appears as a white or almost white crystalline powder. It is highly soluble in water, which makes it appear clear when dissolved. The compound is usually odorless.

Comment on solubility

Solubility of 4-[1-[hydroxy(phenoxy)phosphoryl]pentylamino]-4-oxo-butanoic acid

The solubility of 4-[1-[hydroxy(phenoxy)phosphoryl]pentylamino]-4-oxo-butanoic acid (C4H11O3PS) is an intriguing subject due to its complex molecular structure. This compound contains several functional groups that could influence its solubility characteristics:

  • Hydrophilic Groups: The presence of hydroxyl and phosphoryl groups tends to enhance water solubility by allowing the molecule to form hydrogen bonds with water.
  • Hydrophobic Elements: Meanwhile, the phenyl ring may introduce some hydrophobic character that could decrease solubility in polar solvents.
  • pH Sensitivity: The carboxylic acid functional group may become ionized at physiological pH, which can further increase solubility in aqueous solutions.

In summary, the solubility of this compound can be described as:

  1. Moderately soluble in water due to its polar groups.
  2. Potentially soluble in organic solvents that better accommodate its hydrophobic characteristics.
  3. Varying solubility based on pH levels, which could allow for its use in specific applications.

Overall, understanding the solubility of this compound is crucial for predicting its behavior in various environments and applications.

Interesting facts

Interesting Facts about 4-[1-[hydroxy(phenoxy)phosphoryl]pentylamino]-4-oxo-butanoic acid

This intriguing compound, often referred to in the field of bioorganic chemistry, is notable for its multifunctional properties and applications. Here are some fascinating aspects that highlight its significance:

  • Bioactivity: This compound contains a phosphoryl group, which is essential in many biological processes, including energy transfer and signal transduction.
  • Synthesis: The synthesis of this compound involves intricate organic reactions, showcasing the interplay between organic and inorganic chemistry. It emphasizes the importance of phosphoric acid derivatives in organic synthesis.
  • Applications: The unique structure makes this compound a candidate for pharmaceutical applications, particularly in drug design for targeting specific biological pathways.
  • Structure-Activity Relationship (SAR): The compound's design allows for modifying its functional components, which can enhance its efficacy or reduce toxicity in biological systems.
  • Environmental Impact: The study of phosphorus-containing compounds is crucial in understanding their environmental fate and the development of biodegradable materials.

As a chemistry student or a scientist, delving into compounds like 4-[1-[hydroxy(phenoxy)phosphoryl]pentylamino]-4-oxo-butanoic acid opens up discussions about the evolution of synthetic methods and their practical implications. Drawn from nature and transformed through chemical ingenuity, such compounds exemplify the vast potential of organic chemistry in solving real-world problems.

In the words of a renowned chemist: "Chemistry is the art of persuasion, where substances are transformed into tools for innovation."

Synonyms
PD036616