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4-(1-Naphthyl)butanoic acid

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Identification
Molecular formula
C14H14O2
CAS number
133-32-4
IUPAC name
4-(1-naphthyl)butanoic acid
State
State

At room temperature, 4-(1-Naphthyl)butanoic acid is typically found in a solid state.

Melting point (Celsius)
87.00
Melting point (Kelvin)
360.15
Boiling point (Celsius)
413.60
Boiling point (Kelvin)
686.75
General information
Molecular weight
214.27g/mol
Molar mass
214.2600g/mol
Density
1.1990g/cm3
Appearence

4-(1-Naphthyl)butanoic acid appears as a white to off-white crystalline powder. It is typically stable at room temperature and pressure.

Comment on solubility

Solubility of 4-(1-naphthyl)butanoic acid

4-(1-naphthyl)butanoic acid, an aromatic carboxylic acid, displays some intriguing properties when it comes to its solubility. Here are some key points regarding its solubility:

  • Solvent Dependence: This compound is generally soluble in organic solvents such as ethanol and acetone, but its solubility in water is limited.
  • Hydrophobic Character: The presence of the naphthyl group contributes to its hydrophobic nature, which further restricts its solubility in polar solvents such as water.
  • pH Influence: At lower pH levels, the carboxylic acid group may remain protonated, reducing overall solubility in aqueous environments. However, at higher pH levels, deprotonation can enhance solubility.
  • Temperature Effects: Solubility can also increase with temperature; thus, heating organic solvents may facilitate the dissolution of 4-(1-naphthyl)butanoic acid.

To summarize, 4-(1-naphthyl)butanoic acid exhibits limited solubility in water but can dissolve effectively in various organic solvents. Its solubility characteristics highlight the impact of molecular structure and environmental conditions on a compound’s behavior in different solvents.

Interesting facts

Interesting Facts about 4-(1-Naphthyl)butanoic Acid

4-(1-Naphthyl)butanoic acid, often referred to in the scientific community for its unique structural attributes, is an interesting compound with notable applications and characteristics:

  • Biological Significance: This compound has been studied for its potential as an anti-inflammatory agent. Its naphthyl group contributes to specific interactions with biological targets, enhancing its therapeutic profile.
  • Synthetic Utility: It serves as an important intermediate in organic synthesis. The presence of both the naphthalene and butanoic acid moieties allows for varied reactivity, making it versatile in developing more complex molecules.
  • Structure-Activity Relationships: The unique combination of a naphthyl group with a butanoic acid functional group has made it a subject of interest in medicinal chemistry. Researchers often explore how variations in the structure influence biological activity, potentially leading to safer and more effective drugs.
  • Environmental Impact: As a compound that can be part of pharmaceuticals, there's ongoing research regarding its environmental persistence and potential toxicity, emphasizing the need for responsible chemical use and disposal.

In summary, 4-(1-naphthyl)butanoic acid continues to be a compound of interest in various fields of research. From its role in drug discovery to its synthetic applications, its study is both complex and rewarding. As one researcher noted, “The interplay of structure and function in compounds like this one reveals a deeper understanding of chemistry and its implications for human health.”

Synonyms
1-Naphthalenebutanoic acid
4-(naphthalen-1-yl)butanoic acid
970-854-5
781-74-8
1-Naphthalenebutyric acid
GAMMA-(1-NAPHTHYL)BUTYRIC ACID
4-Naphthalen-1-yl-butyric acid
4-(1-naphthyl)butanoic acid
4-(1-naphthyl) butyric acid
SCHEMBL2314388
DTXSID70228734
NSC3046
LZVCOUNJXYIOQA-UHFFFAOYSA-N
NSC 3046
NSC-3046
AKOS013528140
DS-003125
CS-0270334
EN300-1839958