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PCMT (4-(1-piperidyl)cyclohexyl 3,4,5-trimethoxybenzoate)

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Identification
Molecular formula
C21H31NO5
CAS number
40054-69-1
IUPAC name
[4-(1-piperidyl)cyclohexyl] 3,4,5-trimethoxybenzoate
State
State

At room temperature, the compound is in a solid state. It is stable under normal conditions and does not easily vaporize.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
379.48g/mol
Molar mass
379.4970g/mol
Density
1.2050g/cm3
Appearence

The compound typically appears as a white crystalline powder, though in some forms or purities it may be off-white. It is not particularly hygroscopic and demonstrates low volatility at room temperature.

Comment on solubility

Solubility of [4-(1-piperidyl)cyclohexyl] 3,4,5-trimethoxybenzoate

The solubility of [4-(1-piperidyl)cyclohexyl] 3,4,5-trimethoxybenzoate can be influenced by several key factors that warrant attention. Understanding the solubility characteristics of this compound not only helps in its practical applications but also in predicting its behavior in various environments. Here are some aspects to consider:

  • Polar vs. Non-Polar Solvents: The presence of multiple methoxy groups (–OCH3) within the structure suggests that this compound has some affinity for polar solvents, such as water or alcohol.
  • Hydrophobic Character: The cyclohexyl and piperidyl groups contribute to a hydrophobic nature, potentially decreasing its overall solubility in aqueous environments.
  • Temperature Effects: Generally, the solubility of many organic compounds tends to increase with temperature. Thus, heating the solvent could enhance the solubility of this compound.
  • pH Sensitivity: Being a benzoate derivative, the solubility may also vary with changes in pH, potentially affecting the ionization of the carboxylate group.

In summary, while [4-(1-piperidyl)cyclohexyl] 3,4,5-trimethoxybenzoate can display solubility in various solvents, its degree of solubility will depend significantly on the solvent's polarity, temperature, and pH. It's always fascinating to explore how molecular structure directly impacts solubility behavior!

Interesting facts

Interesting Facts about [4-(1-piperidyl)cyclohexyl] 3,4,5-trimethoxybenzoate

[4-(1-piperidyl)cyclohexyl] 3,4,5-trimethoxybenzoate, a fascinating compound, is noteworthy for several reasons. First, it is a structural derivative of benzoic acid and plays a critical role in medicinal chemistry. Here are some interesting points about this compound:

  • Structural Diversity: The presence of both the piperidyl and the trimethoxy groups contributes to the compound's unique structural characteristics, making it an interesting subject for synthesis and modification.
  • Biological Activity: Compounds featuring piperidine derivatives are often explored for their potential pharmacological properties, including their capacity to interact with various neurotransmitter receptors.
  • Research Interest: Given the implications of this compound in drug design, it has attracted attention in fields such as neuropharmacology and therapeutic development.
  • Application Potential: The compound's unique structure suggests potential applications in developing treatments for neurological disorders or analgesic therapies.

As noted in recent studies, “the modification of benzoate esters can lead to compounds with enhanced selectivity and lower side effects in pharmacological applications.” This highlights the importance of compounds like [4-(1-piperidyl)cyclohexyl] 3,4,5-trimethoxybenzoate in modern drug discovery. Furthermore, the interplay between cyclic structures and substituents opens pathways to innovative medicinal applications.

In conclusion, [4-(1-piperidyl)cyclohexyl] 3,4,5-trimethoxybenzoate exemplifies the intricate relationship between chemical structure and biological activity, making it a valuable compound in the ongoing quest for new pharmaceuticals.

Synonyms
1532-12-3
BENZOIC ACID, 3,4,5-TRIMETHOXY-, 4-PIPERIDINOCYCLOHEXYL ESTER
3,4,5-Trimethoxybenzoic acid 4-piperidinocyclohexyl ester
BRN 1265757
Cyclohexanol, 4-piperidino-, 3,4,5-trimethoxybenzoate
DTXSID50165279
DTXCID1087770
(4-piperidin-1-ylcyclohexyl) 3,4,5-trimethoxybenzoate