Tandospirone | Solubility of Things

Identification

Molecular formula

C₂₁H₂₉N₃O₂PS

CAS number

84206-80-4

IUPAC name

4-(1-piperidylmethyl)-3,4-dihydro-2H-1-benzothiepin-5-one

State

The compound is typically a solid at room temperature. It is stable under normal conditions and should be stored in a cool, dry place.

Melting point (Celsius)

218.00

Melting point (Kelvin)

491.15

Boiling point (Celsius)

422.00

Boiling point (Kelvin)

695.15

General information

Molecular weight

383.98g/mol

Molar mass

383.9840g/mol

Density

1.1800g/cm³

Appearence

Tandospirone typically appears as a white to off-white crystalline powder. The compound is relatively soluble in water, resulting in a clear, colorless solution.

Comment on solubility

Solubility of 4-(1-piperidylmethyl)-3,4-dihydro-2H-1-benzothiepin-5-one

The solubility of 4-(1-piperidylmethyl)-3,4-dihydro-2H-1-benzothiepin-5-one can be influenced by various factors, including its chemical structure and the solvent used. This compound, characterized by the presence of a benzothiepin moiety, typically exhibits the following solubility characteristics:

Polar Solvents: It is likely to show moderate solubility in polar solvents due to the presence of nitrogen in the piperidine ring, which can interact favorably with polar molecules.
Non-Polar Solvents: The non-polar characteristics of the benzothiepin portion may lead to limited solubility in non-polar solvents.
Water Solubility: Due to its complex structure, water solubility can be expected to be low, which is typical for many organic compounds with large hydrophobic regions.

In summary, the solubility of 4-(1-piperidylmethyl)-3,4-dihydro-2H-1-benzothiepin-5-one is best described as moderate in polar solvents and limited in non-polar environments. This influences its behavior in various chemical applications and formulations.

Interesting facts

Interesting Facts about 4-(1-piperidylmethyl)-3,4-dihydro-2H-1-benzothiepin-5-one

4-(1-piperidylmethyl)-3,4-dihydro-2H-1-benzothiepin-5-one is an intriguing compound that has garnered attention in the field of medicinal chemistry. Its structure features a benzothiepin core, which is a fused ring system composed of both benzene and thiophene, providing unique chemical properties. Below are some fascinating aspects of this compound:

Therapeutic Potential: This compound is primarily researched for its potential use in treating various neurological and psychiatric disorders, thanks to its structural likeness to other known psychoactive agents.
Biological Activity: Studies suggest that it may exhibit properties such as antidepressant and anxiolytic effects, making it a candidate for further pharmacological exploration.
Structural Diversity: The presence of the piperidine moiety enhances its interaction with biological targets, allowing it to modulate neurotransmitter systems effectively.
Research Significance: With the increasing prevalence of mood disorders, compounds like this one are crucial to discovering new therapies that can provide relief for patients.

Additionally, its complex structure not only poses challenges in synthesis but also provides ample opportunities for modifications that can lead to improved efficacy and reduced side effects. As researchers delve deeper into the pharmacokinetics and mechanisms of action for this compound, it holds the promise of contributing valuable insights into the development of next-generation therapeutic agents. Exploring such compounds enhances our understanding of molecular interactions and therapeutic possibilities.

In conclusion, 4-(1-piperidylmethyl)-3,4-dihydro-2H-1-benzothiepin-5-one exemplifies how a single compound can encapsulate a wealth of potential both scientifically and therapeutically.