Skip to main content

Diazoxide

ADVERTISEMENT
Identification
Molecular formula
C8H7N2O2S2
CAS number
364-98-7
IUPAC name
4-[(1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide
State
State
Diazoxide is typically found in a solid state at room temperature in the form of a powder. It is known for being stable under normal conditions and is commonly used in the medical field as a potassium channel activator.
Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
229.23g/mol
Molar mass
229.2320g/mol
Density
1.3500g/cm3
Appearence

Diazoxide typically appears as white to off-white crystalline powder. It is odorless and stable under normal conditions.

Comment on solubility

Solubility of 4-[(1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide

The solubility of 4-[(1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide in various solvents is a crucial aspect to consider for its practical applications. This compound features multiple thiadiazine rings, which greatly influence its interaction with solvents.

Key Points on Solubility:

  • Polar Solvents: Compounds with sulfur and nitrogen atoms like thiadiazines often exhibit better solubility in polar solvents due to dipole interactions.
  • Non-Polar Solvents: The presence of high molecular weight and complexity may limit solubility in non-polar solvents.
  • Temperature Effects: Increasing temperature can increase solubility as it enhances molecular motion, aiding the dissolution process.

It is generally observed that:

  1. Solubility may improve dramatically in solvents such as water (due to hydrogen bonding) and dimethyl sulfoxide (DMSO).
  2. In contrast, solubility in organic solvents like hexane tends to be limited.

Exploring the solubility behavior of this compound can lead to innovative uses in various chemical processes and formulations, highlighting the importance of solvent choice and conditions in achieving optimal solubility.

Interesting facts

Interesting Facts About 4-[(1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide

The compound 4-[(1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide belongs to a fascinating class of sulfur-containing heterocyclic compounds known as thiadiazinanes. These compounds are notable for their unique structure, which features embedded sulfur and nitrogen atoms, making them significantly reactive and interesting for various applications.

Key Characteristics

  • Heterocyclic Nature: The presence of both sulfur and nitrogen atoms in a cyclic structure contributes to the compound's unique chemical properties.
  • Versatile Reactivity: Due to its dioxo groups and thiadiazine framework, this compound exhibits reactivity patterns that can be exploited in organic synthesis.
  • Biological Applications: Compounds within this family have been studied for their bioactive properties, which may lead to the discovery of new pharmaceutical agents.

The interplay of sulfur and nitrogen in thiadiazines is not merely structural; it imparts unique electronic characteristics that may enhance the compound's performance in chemical reactions. As a student of chemistry, one might find it intriguing to explore how slight modifications of such compounds can lead to drastically different properties or biological activities.

Quote: “The magic of chemistry lies in the transformation of simple elements into complex structures with remarkable properties.” This compound exemplifies this magic, showcasing the potential for innovation in synthetic chemistry.

In summary, 4-[(1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide is not just a compound defined by its formula; it opens doors to a rich field of study centered around thiadiazine chemistry, with implications for both practical applications and theoretical research.

Synonyms
TAUROLIDINE
19388-87-5
Taurolin
Tauroline
Taurolidina
Taurolidinum
Cyclo-taurolidine
(cyclo)-taurolidine
4-[(1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide
8OBZ1M4V3V
W-3100M
DTXSID00173001
DEFENCATH COMPONENT TAUROLIDINE
TAUROLOCK COMPONENT TAUROLIDINE
4-((1,1-dioxo-1,2,4-thiadiazinan-4-yl)methyl)-1,2,4-thiadiazinane 1,1-dioxide
4-((1,1-dioxo-1lambda6,2,4-thiadiazinan-4-yl)methyl)-1lambda6,2,4-thiadiazinane-1,1-dione
4-[(1,1-dioxo-1lambda6,2,4-thiadiazinan-4-yl)methyl]-1lambda6,2,4-thiadiazinane-1,1-dione
bis(1,1-dioxo-perhydro-1,2,4-thiadiazinyl-4)methane
DTXCID7095492
B05CA05
Bis(1,1-dioxoperhydro-1,2,4-thiadiazinyl-4)-methane
Bis-(1,1-dioxoperhydro-1,2,4-thiadiazinyl-4)methane
4,4'-methylenebis-(tetrahydro-1,2,4-thiadiazine-1,1-dioxide)
243-016-5
RefChem:187532
Taurolidin
MFCD00865076
4,4'-methylenebis(1,2,4-thiadiazinane 1,1-dioxide)
4,4'-Methylenebis(tetrahydro-1,2,4-thiadiazine 1,1-dioxide)
Taurolidine (INN)
TAUROLIDINE [INN]
C7H16N4O4S2
4,4 inverted exclamation mark -Methylenebis(1,2,4-Thiadiazinane 1,1-Dioxide)
Taurolidinum [INN-Latin]
Taurolidina [INN-Spanish]
Taurolidine [INN:BAN]
EINECS 243-016-5
UNII-8OBZ1M4V3V
2H-1,2,4-Thiadiazine, 4,4'-methylenebis[tetrahydro-, 1,1,1',1'-tetraoxide; 4,4'-Methylenebis(perhydro-1,2,4-thiadiazin 1,1-dioxide); Taurolidine; Taurolin; Tauroline
TAUROLIDINE [MI]
TAUROLIDINE [MART.]
SCHEMBL65313
TAUROLIDINE [WHO-DD]
orb1299733
CHEMBL2105420
GTPL13030
CHEBI:135173
Defencath (taurolidine + heparin)
HMS5083J20
s4885
Taurolidine, >97% (NMR), powder
2H-1,2,4-Thiadiazine, 4,4'-methylenebis[tetrahydro-, 1,1,1',1'-tetraoxide
AKOS015896472
AC-1423
CCG-267310
CS-W012238
DB12473
FT15603
HY-W011522
NCGC00388398-01
LS-13376
SY102297
NS00005236
T3980
D07146
D78247
EN300-18563487
SR-01000872621
Q3981568
SR-01000872621-2
BRD-K98765504-001-01-5
4,4'-Methylenebis(perhydro-1,2,4-thiadiazin 1,1-dioxide)
4,4'-METHYLENE-BIS(TETRAHYDRO-1,2,4-THIADIAZINE-1,1-DIOXIDE)
4-[(1,1-Dioxido-1,2,4-thiadiazinan-4-yl)methyl]-1,2,4-thiadiazinane 1,1-dioxide #