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4-(1,3-benzothiazol-2-ylsulfanyl)morpholine

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Identification
Molecular formula
C11H12N2OS2
CAS number
60411-29-2
IUPAC name
4-(1,3-benzothiazol-2-ylsulfanyl)morpholine
State
State

At room temperature, 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine is in a solid state.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
358.00
Boiling point (Kelvin)
631.15
General information
Molecular weight
238.34g/mol
Molar mass
238.3370g/mol
Density
1.3300g/cm3
Appearence

4-(1,3-benzothiazol-2-ylsulfanyl)morpholine is typically found as a crystalline solid. The crystals can range in color from off-white to pale yellow, depending on the purity and the specific form.

Comment on solubility

Solubility of 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine

4-(1,3-benzothiazol-2-ylsulfanyl)morpholine demonstrates interesting solubility characteristics due to its unique chemical structure. Understanding its solubility can provide insights into its behavior in various environments and potential applications.

  • Polar and Non-Polar Characteristics: The presence of both benzothiazole and morpholine rings contributes to a complex polar and non-polar interaction, influencing its solubility in different solvents.
  • Solvent Compatibility: This compound is likely soluble in organic solvents such as:
    • Dimethyl sulfoxide (DMSO)
    • Ethanol
    • Acetone
  • Water Solubility: While the benzothiazole moiety can lend some polar characteristics, the overall solubility in water may remain limited due to steric hindrance and hydrophobic interactions.

To encapsulate, it can be said that:

  • The solubility of 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine is primarily governed by its structure.
  • Its affinity for organic solvents suggests potential use in the pharmaceutical field, especially in drug formulation.
  • Experimentation is essential to determine the precise solubility characteristics under varying conditions.

In summary, the solubility of 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine offers a rich area for study, with implications that extend into various scientific disciplines.

Interesting facts

Interesting Facts about 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine

4-(1,3-benzothiazol-2-ylsulfanyl)morpholine is a fascinating compound with significant implications in various fields of science, particularly in medicinal chemistry and organic synthesis. Here are some key points that highlight its unique characteristics:

  • Versatile Structure: This compound features a morpholine ring, which is a six-membered heterocyclic structure containing both nitrogen and oxygen. This allows for a variety of chemical reactions and modifications, making it a versatile building block in organic synthesis.
  • Biological Activity: Compounds that contain the benzothiazole moiety have been studied for their potential biological activities. They are often investigated for their anti-inflammatory, antimicrobial, and anti-cancer properties. The unique attachment of a sulfanyl group in this compound may enhance its reactivity and biological efficacy.
  • Application in Drug Design: The pharmacophore that combines the morpholine and benzothiazole structures may play a crucial role in the development of novel therapeutic agents. Researchers often explore such compounds for their ability to inhibit specific biological targets.
  • Potential for Research: The distinct nature of 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine makes it a point of interest for scientists focused on developing new materials and drugs. The reactions it undergoes could lead to the discovery of compounds with enhanced properties.
  • Interdisciplinary Importance: This compound contributes to interdisciplinary research exploring the intersections of chemistry, biology, and pharmacology. Its unique properties can spark new ideas for studies in related fields.

As chemists continue to unlock the potential of such compounds, 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine could offer exciting opportunities for the development of innovative solutions in healthcare and beyond.

Synonyms
102-77-2
2-(Morpholinothio)benzothiazole
4-(Benzo[d]thiazol-2-ylthio)morpholine
Sulfenamide M
Morpholinylmercaptobenzothiazole
Santocure MOR
Sulfenax MOR
Vulcafor BSM
Vulkacit MOZ
NOBS Special
Usaf cy-7
Accel NS
AMAX
Meramide M
Delac MOR
4-(1,3-benzothiazol-2-ylsulfanyl)morpholine
2-(4-Morpholinothio)benzothiazole
2-(4-Morpholinylthio)benzothiazole
Morpholine, 4-(2-benzothiazolylthio)-
Vulcafor SSM
2-(4-Morpholinylmercapto)benzothiazole
Cure-rite OBTS
2-Benzothiazolesulfenemorpholide
N-Oxydiethylenebenzothiazole-2-sulfenamide
Benzothiazolyl-2-sulfenmorpholide
N-(Oxydiethylene)benzothiazole-2-sulfenamide
Benzothiazole, 2-(4-morpholinylthio)-
2-(4-Morpholino)thiobenzothiazole
2-Morpholinothiobenzothiazole
2-Benzothiazolylsulfenyl morpholine
N-Oxydiethylene-2-benzothiazylsulfenamide
4-(2-Benzothiazolylthio)morpholine
Meramid M
2-Benzothiazolyl N-morpholino sulfide
BENZOTHIAZOLE, 2-(MORPHOLINOTHIO)-
N-(Oxydiethylene)benzothiazylsulfenamide
2-Benzothiazolylsulfenylmorpholine
2-Benzothiazolesulfenamide, N-morpholinyl-
NSC 70078
N-(Oxodiethylene)-2-benzothiazolesulfenamide
CCRIS 4911
N,N-(Oxydiethylene)-2-benzothiazylsulfenamide
N,N-(Oxydiethylene)benzothiazole-2-sulfenamide
HSDB 2867
N-Oxydiethylene-2-benzothiazole sulfenamide
2-benzothiazolyl-n-morpholinosulfide
EINECS 203-052-4
NSC-70078
2-(morpholin-4-ylsulfanyl)-1,3-benzothiazole
BRN 0191684
VCD7623F3K
AI3-27134
Morpholinylmercapto-benzo-thiazole
2-(4-Morpholino)thiobenzothiazole [HSDB]
(2-Morpholinothio)benzothiazole
DTXSID0021096
EC 203-052-4
4-27-00-01868 (Beilstein Handbook Reference)
NSC70078
NCGC00042523-02
NCGC00042523-03
N-Oxydiethylene-2-benzothiazolesulfenamide
2-(morpholin-4-ylthio)-1,3-benzothiazole
N-(Oxydiethylene)-2-benzothiazolesulfenamide
N,N-(Oxydiethylene)-2-benzothiazolesulfenamide
DTXCID201096
CAS-102-77-2
UNII-VCD7623F3K
Accelerator NC
2-(Morpholinthio)-benzothiazole
2-(4-morpholinothiobenzothiazole
Curerite OBTS
2(4-morpholinyl-thio)-benzothiazole
4-(2-Benzothiazolylthio)-morpholine
MFCD00022870
NOBS
OBTS
NCIOpen2_003384
SCHEMBL79658
2(morpholinothio)benzothiazole
MLS000055410
2Benzothiazolesulfenemorpholide
Benzothiazolyl2sulfenmorpholide
2(4Morpholino)thiobenzothiazole
2Benzothiazolylsulfenylmorpholine
2(4Morpholinylthio)benzothiazole
4(2Benzothiazolylthio)morpholine
CHEMBL1530581
Benzothiazole, 2(morpholinothio)
MHKLKWCYGIBEQF-UHFFFAOYSA-
2Benzothiazolylsulfenyl morpholine
2-morpholinosulphenyl-benzothiazole
HMS1760H22
HMS2163A20
HMS3323A19
2Benzothiazolyl Nmorpholino sulfide
Benzothiazole, 2(4morpholinylthio)
Morpholine, 4(2benzothiazolylthio)
2-(4-morpholinothio)-benzothiazole
4-(2-benzothiazolylthio)-morpholin
2(4Morpholinylmercapto)benzothiazole
Tox21_110976
2-morpholin-4-ylsulfanylbenzothiazole
NOxydiethylene2benzothiazylsulfenamide
2-Benzothiazolesulfenamide, N-morphol
2Benzothiazolesulfenamide, Nmorpholinyl
AKOS001025507
N(Oxydiethylene)benzothiazylsulfenamide
Tox21_110976_1
DB14202
2-(MORPHOLINOTHIO)-BENZOTHIAZOLE
WLN: T56 BN DSJ CS-AT6N DOTJ
2-BENZOTHIAZOLYLSUFENYL MORPHOLINE
N(Oxodiethylene)2benzothiazolesulfenamide
N(Oxydiethylene)benzothiazole2sulfenamide
BS-42257
N,N(Oxydiethylene)2benzothiazylsulfenamide
SMR000066103
2-(4-Morpholinylthio)-1,3-benzothiazole
N,N(Oxydiethylene)benzothiazole2sulfenamide
HY-139432
CS-0201154
M0532
NS00004147
E78169
SBI-0653848.0001
2-(4-Morpholinylsulfanyl)-1,3-benzothiazole #
EN300-1726082
BRD-K97360717-001-07-6
BRD-K97360717-001-09-2
Q27291760
Z56821717
InChI=1/C11H12N2OS2/c1-2-4-10-9(3-1)12-11(15-10)16-13-5-7-14-8-6-13/h1-4H,5-8H2