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Lenalidomide

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Identification
Molecular formula
C13H13N3O3
CAS number
191732-72-6
IUPAC name
4-(1,3-dioxoisoindolin-2-yl)-N,N-diethyl-butanamide
State
State

At room temperature, lenalidomide is a solid compound.

Melting point (Celsius)
269.40
Melting point (Kelvin)
542.60
Boiling point (Celsius)
504.80
Boiling point (Kelvin)
777.90
General information
Molecular weight
259.26g/mol
Molar mass
259.2620g/mol
Density
1.3790g/cm3
Appearence

Lenalidomide appears as an off-white to pale-yellow crystalline powder.

Comment on solubility

Solubility Insights for 4-(1,3-dioxoisoindolin-2-yl)-N,N-diethyl-butanamide

The solubility of 4-(1,3-dioxoisoindolin-2-yl)-N,N-diethyl-butanamide can vary significantly depending on several factors such as temperature, solvent type, and pH. Notably, this compound features a complex structure that may influence its solubility properties.

Key Factors Influencing Solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents like water, whereas more hydrophobic sections may favor organic solvents.
  • Temperature: As with many compounds, increasing temperature typically increases solubility, although there are exceptions based on specific interactions.
  • pH Level: The ionization state of the compound may change with pH, affecting its solubility in aqueous solutions.

As a general guideline, compounds similar to 4-(1,3-dioxoisoindolin-2-yl)-N,N-diethyl-butanamide often exhibit:

  • Moderate solubility in organic solvents (e.g., ethanol, methanol)
  • Lower solubility in highly polar solvents unless specific interactions promote solvation

Researchers often say, "the structure of a molecule governs its solubility." In this case, the unique arrangement of functional groups may lead to intriguing solubility behaviors that warrant further examination through experimental studies.


Interesting facts

Interesting Facts about 4-(1,3-dioxoisoindolin-2-yl)-N,N-diethyl-butanamide

4-(1,3-dioxoisoindolin-2-yl)-N,N-diethyl-butanamide is a fascinating compound that showcases the beauty of organic chemistry and the complexity of molecular interactions. This compound, featuring an isoindoline structure, is notable for several reasons:

  • Versatile Applications: Compounds like this are often investigated for their potential therapeutic uses, particularly in the fields of pharmacology and medicinal chemistry. They may possess bioactive properties that can lead to the development of new drugs.
  • Aromatic Framework: The isoindoline moiety contributes to the stability and reactivity of the molecule, making it a prime candidate for further functionalization and modification. Such changes can tailor the compound's properties for specific applications.
  • Structural Diversity: The presence of functional groups, such as the dioxo moiety, adds layers of complexity, allowing for diverse chemical behaviors. The ability of the compound to form hydrogen bonds can influence its interactions in biochemical systems.
  • Synthetic Pathways: The synthesis of 4-(1,3-dioxoisoindolin-2-yl)-N,N-diethyl-butanamide often involves multiple step reactions, highlighting the ingenuity required in organic synthesis practices. Chemists must navigate challenges related to regioselectivity and stereochemistry.
  • Research Potential: As researchers continue to explore the properties of such compounds, the significance in various fields such as materials science, agriculture, and nanotechnology may become increasingly understood.

In conclusion, the study of 4-(1,3-dioxoisoindolin-2-yl)-N,N-diethyl-butanamide exemplifies the intricate world of chemical compounds where every structure can lead to innovative discoveries and applications. Whether for academic research or industrial applications, the implications of understanding such compounds are vast and promising.

Synonyms
10312-36-4
N,N-Diethyl-1,3-dioxo-2-isoindolinebutyramide
NSC 45503
2-ISOINDOLINEBUTYRAMIDE, N,N-DIETHYL-1,3-DIOXO-
BRN 1543003
N,N-Diethyl-1,3-dihydro-1,3-dioxo-2H-isoindole-2-butanamide
Phthalimide, N-(diethylcarbamoylpropyl)-
1,3-Dioxo-N-diethyl-2-isoindolinebutyramide
2H-Isoindole-2-butanamide, N,N-diethyl-1,3-dihydro-1,3-dioxo-
DTXSID30145650
DTXCID6068141
5-21-10-00482 (beilstein handbook reference)
4-(1,3-dioxoisoindol-2-yl)-N,N-diethylbutanamide
NSC-45503
NSC45503
74896AJW5S
AKOS004107863