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Phenylbutazone

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Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one
State
State

At room temperature, phenylbutazone is typically in a solid state. It is a stable compound under ordinary conditions.

Melting point (Celsius)
105.50
Melting point (Kelvin)
378.65
Boiling point (Celsius)
399.80
Boiling point (Kelvin)
672.95
General information
Molecular weight
308.37g/mol
Molar mass
308.3690g/mol
Density
1.2650g/cm3
Appearence

Phenylbutazone is a white to off-white crystalline powder. It is practically odorless and has a slightly bitter taste. The compound is often used in veterinary medicine for its anti-inflammatory and analgesic properties.

Comment on solubility

Solubility of 4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one

The solubility of 4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one in various solvents is of great interest due to its potential applications in pharmaceuticals and agrochemicals. Understanding its solubility can provide insights into its behavior in biological systems and its manufacturing processes.

Key factors influencing solubility include:

  • Polarity: The compound contains multiple aromatic systems which may suggest a lower solubility in polar solvents.
  • Hydrophobic interactions: Its hydrophobic regions can lead to limited solubility in water, making organic solvents preferable.
  • Temperature: Generally, increased temperature can enhance solubility for many organic compounds.
  • pH levels: As a weak acid or base, the solubility may vary with changes in pH, potentially enhancing solubility in specific conditions.

In practice, it may exhibit moderate to low solubility in water and greater solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO). As stated in various studies, "the solubility profile is vital for the formulation of effective therapeutic agents." Therefore, understanding and optimizing the solubility of this compound could pave the way for better drug delivery systems and increase its efficacy in formulations.


Further investigation into its specific solubility parameters is required, but initial assessments point to its use primarily in non-aqueous environments for optimal function.

Interesting facts

Exploring 4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one

The compound known as 4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one is a fascinating example of pyrazol derivatives that highlights the complexity and beauty of organic chemistry. This particular compound is noteworthy for several reasons:

  • Diverse Applications: The structural features of this compound allow it to act in versatile roles, especially in the fields of pharmaceuticals and agrochemicals. Pyrazol derivatives are often explored for their potential anti-inflammatory, analgesic, and antipyretic properties.
  • Intriguing Structure: The compound boasts a heterocyclic structure that intertwines multiple functional groups. This complexity can affect the reactivity and interactions with biological systems, making it a point of study for medicinal chemistry.
  • Research Interest: Compounds like this one are often the subject of extensive research due to their ability to inhibit specific enzymes or pathways, a feature that is critical when designing new therapeutic agents.
  • Synthetic Pathways: The synthesis of this compound involves intricate reactions that can shed light on the methods of preparing pyrazoles and other heterocycles, contributing to the development of green chemistry approaches.

Moreover, the presence of multiple methyl and phenyl groups within the structure signifies active sites for further modifications and paves the way for creating derivatives with enhanced biological activities. As the chemist, you might enjoy diving into the quantum mechanics and molecular orbital theories that determine the properties of such complex compounds.

Overall, the exploration of 4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one not only enhances our understanding of pyrazole chemistry but also offers insights that may lead to innovative solutions in medicine and other industries. As one researcher aptly put it, "In the compound's complexity lies its potential."

Synonyms
Forbisen
517-83-9
S. N. 475
NSC 14060
BRN 0351034
QP79EQ89N3
NSC-14060
2,2',3,3'-Tetramethyl-1,1'-diphenyl(4,4'-bi-3-pyrazoline)-5,5'-dione
DTXSID70199652
4-26-00-02474 (Beilstein Handbook Reference)
(4,4'-Bi-3-pyrazoline)-5,5'-dione, 2,2',3,3'-tetramethyl-1,1'-diphenyl-
SN-475
(4,4'-BI-3-PYRAZOLINE)-5,5'-DIONE, 1,1'-DIPHENYL-2,2',3,3'-TETRAMETHYL-
(4,4'-Bi-1H-pyrazole)-3,3'-dione, 2,2',3,3'-tetrahydro-1,1',5,5'-tetramethyl-2,2'-diphenyl-
(4,4'-BI-1H-PYRAZOLE)-3,5'(2H,2'H)-DIONE, 1,2',3',5-TETRAMETHYL-1',2-DIPHENYL-
1,2',3',5-TETRAMETHYL-1',2-DIPHENYL(4,4'-BI-1H-PYRAZOLE)-3,5'(2H,2'H)-DIONE
[4,4'-Bi-1H-pyrazole]-3,3'-dione, 2,2',3,3'-tetrahydro-1,1',5,5'-tetramethyl-2,2'-diphenyl-
DTXCID30122143
(4,4'-Bi-3-pyrazoline)-5,5'-dione, 2,2',3,3'-tetramethyl-1,1'-diphenyl-(8CI)
(4,4'-Bi-1H-pyrazole)-3,3'-dione, 2,2',3,3'-tetrahydro-1,1',5,5'-tetramethyl-2,2'-diphenyl-(9CI)
NSC14060
UNII-QP79EQ89N3
SCHEMBL588715
[4,5'-dione, 2,2',3,3'-tetramethyl-1,1'-diphenyl-
2,2'-3,3'-Tetramethyl-1,1'-diphenyl[4,4'-bi-3-pyrazoline]-5,5'-dione
[4,3'-dione, 2,2',3,3'-tetrahydro-1,1',5,5'-tetramethyl-2,2'-diphenyl-
1,1',5,5'-tetramethyl-2,2'-diphenyl-1H,1'H-4,4'-bipyrazole-3,3'(2H,2'H)-dione
4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one