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Nicotine

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Identification
Molecular formula
C10H14N2
CAS number
54-11-5
IUPAC name
4-[(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)methyl]aniline
State
State

Nicotine is typically a liquid at room temperature.

Melting point (Celsius)
-79.00
Melting point (Kelvin)
194.15
Boiling point (Celsius)
247.00
Boiling point (Kelvin)
520.15
General information
Molecular weight
162.23g/mol
Molar mass
162.2360g/mol
Density
1.0100g/cm3
Appearence

Nicotine is a colorless to yellowish oily liquid. When exposed to air, it turns brown and acquires a strong odor.

Comment on solubility

Solubility of 4-[(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)methyl]aniline

The solubility of 4-[(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)methyl]aniline can be quite intricate due to its complex molecular structure. Understanding its solubility characteristics is essential for applications in various chemical processes. Here are some key aspects to consider:

  • Solvent Compatibility: The solubility of this compound may vary significantly in different solvents, with a tendency to dissolve in organic solvents such as ethanol and acetone due to its hydrophobic regions.
  • Influence of pH: The solubility can be affected by pH changes, particularly if the compound can ionize, which may increase solubility in aqueous solutions.
  • Temperature Dependence: Like many compounds, its solubility may increase with temperature; hence, a temperature rise could potentially enhance the dissolution rate in solvents.
  • Hydrophilicity vs. Hydrophobicity: The balance between hydrophilic and hydrophobic functional groups in its structure plays a crucial role in determining how well it will dissolve in water versus organic solvents.

In summary, while the exact solubility values can depend on several factors, it is clear that understanding the solubility of 4-[(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)methyl]aniline is vital for its use in practical applications, especially in pharmacology and material science. Researchers should conduct thorough solubility tests in various solvents and conditions to establish reliable data for this compound.

Interesting facts

Interesting Facts about 4-[(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)methyl]aniline

4-[(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)methyl]aniline is a fascinating compound that showcases the intricate relationships between structure and biological activity. Here are some intriguing aspects of this compound:

  • Chemical Structure: The compound features a unique bicyclic structure, which contributes to its potential efficacy in biological systems. The azabicycle framework is integral to its interactions with various receptors.
  • Pharmaceutical Relevance: Compounds of this nature often serve as intermediates or active pharmaceutical ingredients. Their structure-activity relationship can reveal important insights into drug design and development.
  • Bioactivity Exploration: Research into this compound's biological properties could lead to discoveries in therapeutic areas, including pain relief, cognition enhancement, or even treatment of neurological disorders.
  • Role of Substituents: The presence of specific substituents, such as the aniline moiety, can significantly influence the solubility and binding affinity of the compound to biological targets, making it a subject of interest in medicinal chemistry.
  • Potential for Innovation: As scientists continue to explore the pharmacological properties associated with structural variations, compounds like 4-[(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)methyl]aniline may inspire the development of novel therapeutic agents.

In summary, this compound embodies the complexity and elegance of organic chemistry. Its multifaceted nature sparks curiosity and inspires further research in the realms of medicinal chemistry and pharmacology. As noted by chemists, “Every compound tells a story; it's up to us to decode it.”