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Tryptamine

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Identification
Molecular formula
C10H12N2
CAS number
61-54-1
IUPAC name
4-(1H-indol-3-yl)butan-1-amine
State
State

At room temperature, tryptamine is typically found in its solid state.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
160.22g/mol
Molar mass
160.2210g/mol
Density
1.1696g/cm3
Appearence

Tryptamine appears as an off-white to tan crystalline solid that may also appear as a powder. It is known for its slightly fishy odor.

Comment on solubility

Solubility of 4-(1H-indol-3-yl)butan-1-amine

The solubility of 4-(1H-indol-3-yl)butan-1-amine is influenced by several factors including its structure and the presence of functional groups. In general, compounds like this one that contain an indole moiety tend to exhibit the following solubility characteristics:

  • Polarity: The indole group often increases the hydrophobic character of the compound, making it less soluble in polar solvents like water.
  • Solvent Dependence: It is likely to have moderate solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), which can better accommodate its hydrophobic regions.
  • Temperature Impact: As with many amines, increasing the temperature may enhance solubility in appropriate solvents, allowing better interaction.
  • pH Influence: The solubility of this compound may also change significantly with pH levels due to its amine group, possibly rendering it more soluble under acidic conditions where it can exist in protonated forms.

In summary, while 4-(1H-indol-3-yl)butan-1-amine may not be highly soluble in water, it potentially exhibits favorable solubility characteristics in various organic solvents, especially when adjusted for temperature and pH conditions. As always, performing empirical solubility tests is recommended for precise applications.

Interesting facts

Interesting Facts about 4-(1H-indol-3-yl)butan-1-amine

4-(1H-indol-3-yl)butan-1-amine, often referred to in scientific literature, is a compound that has garnered attention for its potential applications in various fields. Here are some fascinating insights:

  • Biological Significance: This compound is structurally related to several bioactive compounds, indicating its potential role in biological systems. It interacts with receptors that are crucial to neurotransmission, suggesting possible implications in neuropharmacology.
  • Indole Framework: The indole ring is a prominent feature of this molecule, known for its prevalence in natural products and biologically active compounds. This framework is essential for the chemistry of many pharmaceuticals, making the study of such compounds valuable in drug discovery.
  • Diverse Applications: Researchers are exploring the utility of 4-(1H-indol-3-yl)butan-1-amine in:
    • Psychoactive substances
    • Antidepressants and anxiolytics
    • As a building block for more complex organic molecules
  • Research Frontiers: The study of indole derivatives is a rich field, with ongoing research focusing on the relationship between their structure and biological activity. The chemical reactivity of this compound opens pathways to new synthetically derived materials.
  • Environmental Considerations: Like many amines, 4-(1H-indol-3-yl)butan-1-amine is subject to investigation for its environmental impact, particularly regarding its breakdown and interaction with ecosystem components.

In summary, 4-(1H-indol-3-yl)butan-1-amine is more than just a chemical compound; it embodies a wealth of scientific inquiry and potential. Its distinctive structure and properties position it as a noteworthy subject in the quest for new therapeutics and understanding biological processes.

Synonyms
4-(1H-indol-3-yl)butan-1-amine
669-70-5
Butylamine, 4-[3-indolyl]-
3-(aminobutyl)indole
4-(1h-indol-3-yl)butylamine
SCHEMBL1249795
GZQBGZWAALHNBW-UHFFFAOYSA-N
AAA66970
AKOS013786106
4-(1H-Indol-3-yl)-1-butanamine #
DB-331502
EN300-173433