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Tryptamine

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Identification
Molecular formula
C10H12N2
CAS number
61-54-1
IUPAC name
4-(1H-indol-3-yl)butan-2-amine
State
State

At room temperature, tryptamine is often found as a solid in the form of crystalline powder.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.00
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.00
General information
Molecular weight
160.22g/mol
Molar mass
160.2230g/mol
Density
1.1690g/cm3
Appearence

Tryptamine is typically a white to slightly yellow crystalline powder. It may appear as needle-like crystals when purified.

Comment on solubility

Solubility of 4-(1H-indol-3-yl)butan-2-amine

4-(1H-indol-3-yl)butan-2-amine, a compound that showcases interesting structural properties, presents intriguing solubility characteristics. When considering the solubility of this compound, several factors come into play:

  • Polarity: The presence of both the indole ring and the amine group suggests a degree of polarity, which can enhance solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The amine group can participate in hydrogen bonding, further increasing solubility in aqueous environments
  • Solvent Effects: While this compound may dissolve well in polar solvents such as water and ethanol, it is likely to have limited solubility in non-polar organic solvents.

As with many organic compounds, temperature also plays a crucial role in solubility. Typically, an increase in temperature can lead to increased solubility, particularly in non-polar solvents. In summary, the solubility of 4-(1H-indol-3-yl)butan-2-amine is influenced by its molecular structure, leading to a general ability to dissolve in polar solvents, while remaining less soluble in non-polar environments.

Interesting facts

Interesting Facts about 4-(1H-indol-3-yl)butan-2-amine

4-(1H-indol-3-yl)butan-2-amine, also known as 4-(Indol-3-yl)butan-2-amine, is a fascinating compound that falls within the category of indole derivatives. These types of compounds exhibit a wide range of biological activities and have made a significant impact in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Biological Relevance: Compounds that feature an indole moiety are often found in various natural products, particularly those that exhibit important pharmacological effects. Indoles are known for their roles in neurotransmission, inflammation, and as potential antidepressants.
  • Potential Therapeutic Uses: 4-(1H-indol-3-yl)butan-2-amine has garnered attention for its possible application in treating neurological disorders, with studies suggesting it may have neuroprotective properties.
  • Research Highlights: A multitude of studies are dedicated to understanding the mechanisms of indole derivatives. Specific investigations explore their interactions with serotonin receptors, which are critical for mood regulation.
  • Structural Significance: The unique structure of 4-(1H-indol-3-yl)butan-2-amine, characterized by the combination of the indole ring and the aliphatic amine group, contributes to its chemical reactivity and biological interactions, making it an interesting target for synthetic chemists.
  • Synthetic Pathways: Chemists have devised several synthetic methods to produce this compound, many of which emphasize the importance of protecting functional groups during reactions to achieve high yields and purity.

As a compound with connections to both natural and synthetic chemistry, 4-(1H-indol-3-yl)butan-2-amine continues to be a rich subject for research. Its exploration not only helps us better understand complex biochemical pathways but also opens up avenues for the development of novel therapeutic agents.

Synonyms
4-(1H-indol-3-yl)butan-2-amine
15467-30-8
DTXSID00935040
DTXCID101363676
970-294-1
1H-Indole-3-propanamine,a-methyl-
alpha-Methylhomotryptamine
3-(3-Aminobutyl)indole
BRN 0137563
3-(alpha-Ethylaminoethyl) indole
INDOLE, 3-(3-AMINOBUTYL)-
1H-Indole-3-propanamine, alpha-methyl-
5-22-10-00179 (Beilstein Handbook Reference)
SCHEMBL1250035
SCHEMBL29611875
FEIOENIFHULYLW-UHFFFAOYSA-N
QAA46730
AKOS006277658
3-(1H-indol-3-yl)-1-methyl-propylamine
CS-0246562
EN300-333145