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Epinephrine hydrochloride

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Identification
Molecular formula
C9H13NO3·HCl
CAS number
55-31-2
IUPAC name
4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]phenol;hydrochloride
State
State

At room temperature, epinephrine hydrochloride is typically in a solid state in the form of a crystalline powder. It is typically stable under normal conditions of temperature and pressure.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
219.69g/mol
Molar mass
219.6940g/mol
Density
1.3000g/cm3
Appearence

Epinephrine hydrochloride appears as a white or nearly white crystalline powder. It may also be encountered as a crystalline solid. Its appearance can be affected by the level of hydration and minor impurities, but generally, it remains colorless to slightly off-white.

Comment on solubility

Solubility of 4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]phenol; hydrochloride

The solubility of 4-[2-[[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]phenol; hydrochloride can be attributed to its ionic nature and functional groups. As a hydrochloride salt, it tends to exhibit enhanced solubility in aqueous solutions due to the following factors:

  • Ionic Interaction: The presence of the chloride ion facilitates ionic interactions with water molecules, promoting solubility.
  • Hydrogen Bonding: The hydroxyl (-OH) groups in the compound can form hydrogen bonds with water, leading to increased solubility.
  • Temperature Influence: Like many organic compounds, solubility can be influenced by temperature, often increasing with higher temperatures.

However, it's essential to note that the overall solubility may vary depending on the pH of the solution and the presence of other ions. As a general observation, compounds such as this one tend to be more soluble in acidic solutions. Understanding these interactions is crucial for practical applications, such as drug formulation and delivery systems.

Interesting facts

Interesting Facts about 4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]phenol;hydrochloride

This compound, known in the scientific community for its complex structure and unique properties, offers an intriguing perspective into the world of organic chemistry. Here are several interesting facts about it:

  • Medicinal Relevance: The compound has been studied for its potential role in therapeutic applications, primarily due to its ability to interact with specific biological targets within the body.
  • Stereochemistry: Its chiral centers, denoted by (1S,2R), highlight the importance of stereochemistry in pharmaceuticals, affecting not only the activity but also the safety of the compound.
  • Phenolic Structure: The presence of the phenol groups in its structure provides interesting properties, including antioxidant activities, making it a valuable subject of study in biochemistry.
  • Hydrochloride Form: As a hydrochloride salt, this compound likely exhibits increased solubility and stability, which are crucial factors in drug formulation.
  • Research Potential: Ongoing research into its biological effects can lead to discoveries of new therapeutic approaches, especially in the context of diseases that involve oxidative stress.

As stated by prominent chemist Marie Curie, "Nothing in life is to be feared, it is only to be understood." This compound embodies that notion, inviting further understanding and investigation into its potential and function.

In conclusion, the unique properties and potential applications of 4-[2-[[[1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]phenol;hydrochloride render it a fascinating subject for both chemists and pharmacologists alike.

Synonyms
MFCD01657514
MLS002153782
Ritodrinium
DU21220 (hydrochloride)
Benzenemethanol, 4-hydroxy-alpha-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, hydrochloride (1:1), (alphaS)-rel-
SMR001233166
N-(p-Hydroxyphenethyl)-4-hydroxynorephedrine hydrochloride
N-[2-(p-Hydroxyphenyl)ethyl]-N-[2-(p-hydroxyphenyl)-2-hydroxy-1-methylethyl]amine hydrochloride;N-(p-Hydroxyphenylethyl)-4-hydroxyno rephedrine hydrochloride;Du-21220
Prestwick_763
Yutopar (TN)
ritodrin-hydrochloride
NCGC00016773-01
RefChem:1098138
CAS-23239-51-2
SCHEMBL122631
orb1308635
DTXCID6025438
CHEBI:32102
MSK8053
IDLSITKDRVDKRV-XHXSRVRCSA-N
HMS1569E19
Ritodrine HCl - Bio-X trade mark
Tox21_110603
Ritodrine hydrochloride (JP17/USP)
Ritodrine hydrochloride (JP18/USP)
AKOS025117464
AC-3536
CCG-220349
FR27741
AS-12194
BR164351
D01263
T72119
239R512
Ritodrine hydrochloride, British Pharmacopoeia (BP) Reference Standard
Ritodrine hydrochloride, United States Pharmacopeia (USP) Reference Standard
4-(2-(((1R,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl)amino)ethyl)phenol hydrochloride
4-[2-[[(1R,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol;hydrochloride
Ritodrine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]phenol;hydrochloride
Benzenemethanol, 4-hydroxy-?-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, hydrochloride (1:1), (?S)-rel-
Benzenemethanol, 4-hydroxy-|A-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, hydrochloride (1:1), (|AS)-rel-