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Droxidopa

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Identification
Molecular formula
C9H11NO5
CAS number
23651-95-8
IUPAC name
4-[2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxy-ethyl]phenol
State
State

At room temperature, droxidopa is typically in a solid state as a crystalline powder.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.00
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.00
General information
Molecular weight
213.24g/mol
Molar mass
213.2420g/mol
Density
1.3700g/cm3
Appearence

Droxidopa appears as a white to off-white crystalline powder. It is typically odorless and has a bitter taste.

Comment on solubility

Solubility of 4-[2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxy-ethyl]phenol: C9H11NO5

The solubility of 4-[2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxy-ethyl]phenol, with the chemical formula C9H11NO5, can be influenced by several factors. Here are some key considerations:

  • Polarity: Due to the presence of hydroxyl (-OH) and methoxy (-OCH3) groups, this compound exhibits some level of polarity, which may enhance its solubility in polar solvents.
  • Solvent Interaction: It is likely more soluble in aqueous solutions and organic solvents like ethanol, but less soluble in non-polar solvents due to its structural features.
  • Temperature Influence: Solubility can be affected by temperature; generally, an increase in temperature can lead to higher solubility in many cases.
  • pH Levels: The pH of the solution may also impact solubility, especially for compounds that can be ionized.

Overall, while specific solubility data may not be readily available, the factors outlined above provide a framework for predicting how 4-[2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxy-ethyl]phenol behaves in various solvent conditions. Understanding these aspects is crucial for applications involving this chemical compound.

Interesting facts

Interesting Facts About 4-[2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxy-ethyl]phenol

The compound 4-[2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxy-ethyl]phenol, often referred to for its significant biological activities, is a fascinating topic of study among chemists and pharmacologists alike. Here are some essential insights into this intriguing compound:

  • Biological Relevance: This compound has garnered attention due to its potential role in neuropharmacology, primarily as an antidepressant or neuroprotective agent. Its structure suggests that it may interact with various neurotransmitter systems.
  • Structural Complexity: The intricate structure of this compound includes a phenol group and multiple functional groups that contribute to its pharmacological properties. The presence of the dimethoxyphenyl group is particularly noteworthy as it may influence the compound's interaction with biological targets.
  • Synthetic Pathways: Understanding the synthetic pathways of compounds like this one fosters advancements in medicinal chemistry. Scientists often explore various reaction mechanisms to optimize their synthesis.
  • Pharmacokinetics: Given its diverse functional groups, this compound's pharmacokinetic profile—absorption, distribution, metabolism, and excretion—is a crucial area of research, impacting its efficacy and safety in therapeutic applications.
  • Research Applications: Ongoing research aims to elucidate the mechanisms by which this compound exerts its effects, paving the way for new treatments in mental health disorders and neurodegenerative diseases.
  • Quote to Reflect On: As the renowned chemist Linus Pauling famously said, "The best way to have a good idea is to have a lot of ideas." This principle applies to exploring various compounds and their potential.

In summary, 4-[2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxy-ethyl]phenol serves as a compelling subject for scientific inquiry, bridging the realms of organic chemistry and therapeutic development. The ongoing studies related to its biological activity and structural characteristics continue to contribute to our understanding of complex chemical interactions.

Synonyms
4-(2-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-1-hydroxyethyl)phenol
R(-)-Denopamine
4-[2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxyethyl]phenol
CHEMBL75639
SCHEMBL4542605
DTXSID70860931
DB-055569
L000220
(p-hydroxyphenyl)-2-[(3,4-dimethoxyphenethyl) amino]-ethanol