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Sertindole Hydrochloride

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Identification
Molecular formula
C24H30Cl2N3O
CAS number
125638-68-4
IUPAC name
4-[2-[3-(1H-indol-3-yl)pyrrolidin-1-ium-1-yl]ethyl]morpholin-4-ium;dichloride
State
State

At room temperature, Sertindole Hydrochloride is in a solid state. It is often noted for its stability under standard storage conditions.

Melting point (Celsius)
238.00
Melting point (Kelvin)
511.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
469.49g/mol
Molar mass
469.4930g/mol
Density
1.2400g/cm3
Appearence

Sertindole Hydrochloride typically appears as a white to off-white crystalline powder. It is known for its hygroscopic nature, meaning it can absorb moisture from the air, which can impact its appearance over time.

Comment on solubility

Solubility of 4-[2-[3-(1H-indol-3-yl)pyrrolidin-1-ium-1-yl]ethyl]morpholin-4-ium;dichloride

The solubility of the compound 4-[2-[3-(1H-indol-3-yl)pyrrolidin-1-ium-1-yl]ethyl]morpholin-4-ium;dichloride can be characterized as follows:

  • Solvent Interaction: This compound, being an ionic salt due to the presence of the dichloride, is likely to exhibit high solubility in polar solvents, particularly water.
  • Hydrophilicity: The ionic and polar groups present in the molecule contribute significantly to its hydrophilicity, which enhances solubility in aqueous solutions.
  • Temperature Effects: As with many ionic compounds, solubility may increase with temperature; thus, heating the solution may promote dissolution.
  • Potential Challenges: The solubility might be affected by the presence of co-solvents or competing ions in a complex solution environment.

In conclusion, this compound is expected to be readily soluble in water and other polar solvents, making it accessible for various applications in biochemical and pharmaceutical fields. Its unique structure may also imply that while it dissolves well in polar environments, care should be taken when introducing it to non-polar solvents where solubility would likely decrease significantly.

Interesting facts

Interesting Facts About 4-[2-[3-(1H-indol-3-yl)pyrrolidin-1-ium-1-yl]ethyl]morpholin-4-ium;dichloride

The compound 4-[2-[3-(1H-indol-3-yl)pyrrolidin-1-ium-1-yl]ethyl]morpholin-4-ium;dichloride is a fascinating entity in the field of medicinal chemistry. Its complex structure has garnered attention due to its potential pharmacological applications.

Key Features of the Compound

  • Diverse Structural Components: This compound features a unique cationic morpholine and indole framework, known for their roles in various biological activities.
  • Potential Biological Activity: The indole moiety is a common feature in many biologically active compounds, implicated in processes such as neural signaling and cell regulation.
  • Versatility: Morpholine derivatives are often explored for their properties as drug candidates, making this compound of particular interest for pharmaceutical research.
  • Charged Nature: As a salt indicated by the presence of dichloride, this compound could have enhanced solubility and improved pharmacokinetic properties.

Scientific investigations into this compound may reveal insights into how combining different pharmacophores affects biological activity. Given its potential applications, research could aim to elucidate mechanisms of action or to develop derivatives that enhance its therapeutic efficacy.

Research Implications

Future studies may focus on:

  • Investigating the chemical reactivity and stability of the compound under various conditions.
  • Exploring its interactions with biological targets such as receptors or enzymes.
  • Evaluating its efficacy in in vivo models for diseases where indole and morpholine components are beneficial.

As a promising illustration of structure-activity relationships, this compound stands at the intersection of synthetic chemistry and pharmacology, inviting further exploration and discovery.

Synonyms
INDOLE, 3-(1-(2-MORPHOLINOETHYL)-3-PYRROLIDINYL)-, DIHYDROCHLORIDE
3671-02-1
NSC 43513
3-(1-(2-Morpholinoethyl)-3-pyrrolidinyl)-, dihydrochloride
1H-Indole, 3-(1-(2-(4-morpholinyl)ethyl)-3-pyrrolidinyl)-, dihydrochloride