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Meclofenoxate

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Identification
Molecular formula
C21H28Cl2N2O
CAS number
3685-84-5
IUPAC name
[4-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethyl]phenyl]ammonium;dichloride
State
State

At room temperature, Meclofenoxate is a solid.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
291.10
Boiling point (Kelvin)
564.25
General information
Molecular weight
494.37g/mol
Molar mass
494.3650g/mol
Density
1.2000g/cm3
Appearence

Meclofenoxate typically appears as a white crystalline powder. Its appearance may slightly vary depending on the form and purity.

Comment on solubility

Solubility of 4-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethyl]phenyl]ammonium;dichloride

The compound 4-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethyl]phenyl]ammonium;dichloride demonstrates solubility characteristics that are influenced by its unique chemical structure. Given that it is a quaternary ammonium salt, we can summarize its solubility behavior in a few key aspects:

  • Polarity: The presence of the ammonium group can lead to increased polarity, which generally promotes solubility in polar solvents like water.
  • Ionic Nature: As a salt, it is expected to dissolve well in aqueous solutions due to the ionic interactions with water molecules.
  • Hydrophobic and Hydrophilic Balance: The methoxyphenyl and propyl groups introduce hydrophobic characteristics that may affect its overall solubility. Thus, this compound may have better solubility in organic solvents as well.
  • Concentration Dependency: Solubility can vary significantly depending on concentration, temperature, and the specific solvent used.

In summary, while 4-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethyl]phenyl]ammonium;dichloride likely exhibits favorable solubility in water and other polar solvents, the extent of its solubility will be influenced by external factors such as the solvent environment and the specific interactions occurring at the molecular level. Always refer to experimental data for precise solubility values.

Interesting facts

Interesting Facts about the Compound: 4-[2-[3-(3-methoxyphenyl)-3-propyl-pyrrolidin-1-ium-1-yl]ethyl]phenyl]ammonium;dichloride

This compound, noted for its intriguing molecular structure, belongs to a class of chemical compounds that are significant in the realm of medicinal chemistry and pharmacology. Here are several points that highlight its importance:

  • Pharmacological Potential: Compounds similar to this one are often explored for their potential therapeutic effects, particularly in neurological conditions. The pyrrolidine moiety is often associated with central nervous system activity.
  • Ion-Pairing Effects: The presence of the dichloride ion can enhance the solubility of the compound in various solvents, impacting its bioavailability and ensuring that it can interact effectively with biological systems.
  • Structural Complexity: The unique combination of methoxyphenyl and propyl groups contributes to the compound's diverse interactions and possibly its specificity to targets in biochemical pathways.
  • Role in Research: Researchers are particularly interested in compounds with ammonium functional groups due to their charge properties, which can play a crucial role in drug formulation and delivery.
  • Studies and Applications: Preliminary studies suggest its use in developing drugs aimed at moderating neurotransmitter levels, making it a point of interest for further research in mental health treatments.

Overall, this compound serves as a compelling case study in synthetic chemistry and its applications in therapeutic development. As scientists continue to unravel the complexities of chemical interactions, it stands as an example of how intricate design can lead to significant medical advancements. 
“The key to unlocking new therapies often lies in the detailed understanding of chemical structure and its relationship to biological activity.”

Synonyms
Aniline, p-(2-(3-(m-methoxyphenyl)-3-propyl-1-pyrrolidinyl)ethyl)-, dihydrochloride
1-(p-Aminophenethyl)-3-(m-methoxyphenyl)-3-propylpyrrolidine dihydrochloride
1945-00-2
Pyrrolidine, 1-(p-aminophenethyl)-3-(m-methoxyphenyl)-3-propyl-dihydrochloride
Pyrrolidine, 1-(p-aminophenethyl)-3-(m-methoxyphenyl)-3-propyl- dihydrochloride