Skip to main content

Tilidine

ADVERTISEMENT
Identification
Molecular formula
C22H29N3O
CAS number
3583-64-0
IUPAC name
4-[2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)ethyl]morpholine
State
State

Tilidine is typically found as a solid at room temperature and is often used in a liquid formulation for pharmaceutical purposes.

Melting point (Celsius)
74.00
Melting point (Kelvin)
347.15
Boiling point (Celsius)
417.00
Boiling point (Kelvin)
690.15
General information
Molecular weight
311.48g/mol
Molar mass
311.4750g/mol
Density
1.1450g/cm3
Appearence

Tilidine appears as a pale yellow, oily liquid. It is known for its viscous nature and a slight aromatic smell.

Comment on solubility

Solubility of 4-[2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)ethyl]morpholine

The solubility of 4-[2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)ethyl]morpholine can be characterized by several important factors. Given its complex structure, the solubility is influenced by:

  • Polarity: The presence of the morpholine moiety suggests that the compound may exhibit moderate polarity, which could enhance its solubility in polar solvents.
  • Functional Groups: The benzyl group may contribute to solubility in organic solvents, while the diazabicyclic structure can impact intermolecular interactions.
  • Hydrophilicity vs. Hydrophobicity: The balance between hydrophilic and hydrophobic parts of the molecule will dictate its solubility in water versus organic solvents.

In general, molecules with such dual characteristics often show variable solubility depending on the solvent used:

  1. In Polar Solvents: Likely soluble due to the presence of polar functional groups.
  2. In Organic Solvents: Possibility of enhanced solubility owing to hydrophobic interactions from the benzyl group.

As a result, one might expect this compound to:

  • Be soluble in common organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO).
  • Exhibit limited solubility in water due to its larger, hydrophobic structures.

Overall, the solubility characteristics of 4-[2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)ethyl]morpholine are indicative of its complex nature and necessity for careful solvent selection in practical applications.

Interesting facts

Interesting Facts about 4-[2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)ethyl]morpholine

4-[2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)ethyl]morpholine is a fascinating compound with intriguing applications in various fields of chemistry and medicinal science. Here are some interesting aspects of this compound:

  • Structural Diversity: The compound features a morpholine ring, which is a six-membered ring containing one oxygen atom and five carbon atoms. This adds to the structural elegance and functional versatility of the molecule.
  • Diazabicyclo Framework: The presence of a diazabicyclo[3.3.1]nonane structure contributes to the compound's uniqueness. This bicyclic structure can influence the compound's reactivity and interaction with biological systems.
  • Biological Relevance: Compounds similar to this one have been researched for their potential roles in drug development, particularly due to their ability to interact with neurotransmitter systems. They can serve as inhibitors or modulators for various biological targets.
  • Potential Applications: The unique architecture of this compound positions it well for applications in pharmacology, such as the development of analgesics, anxiolytics, or even anti-cancer agents. Its ability to traverse biological membranes makes it an attractive candidate for drug design.
  • Synthesis Challenges: The synthesis of such complex compounds often requires intricate multi-step reactions and specific conditions, which can pose a challenge to chemists but also leads to exciting opportunities for innovation in synthetic methods.

In conclusion, 4-[2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)ethyl]morpholine stands as a prime example of how structural complexity can lead to functional diversity in chemical compounds. Its continued study and exploration could reveal more about its potential advantages in medicinal chemistry and related scientific fields.