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Coomassie Brilliant Blue G-250

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Identification
Molecular formula
C45H44N3O7S2
CAS number
6104-58-1
IUPAC name
4-[2-[3-(hydroxymethyl)-4,6-dioxo-5-[(4-sulfo-1-naphthyl)hydrazono]cyclohex-2-en-1-ylidene]hydrazino]naphthalene-1-sulfonic acid
State
State

At room temperature, Coomassie Brilliant Blue G-250 is typically a solid powder. It is known for its application in staining proteins in laboratories, showing its characteristic blue-color in solution.

Melting point (Celsius)
290.00
Melting point (Kelvin)
563.15
Boiling point (Celsius)
106.00
Boiling point (Kelvin)
379.15
General information
Molecular weight
854.02g/mol
Molar mass
854.0200g/mol
Density
0.8460g/cm3
Appearence

Coomassie Brilliant Blue G-250 appears as a reddish-brown to dark brown powder or solid. When dissolved in water or other solvents, it typically forms a blue-colored solution, which is commonly used in biochemistry to stain proteins.

Comment on solubility

Solubility of 4-[2-[3-(hydroxymethyl)-4,6-dioxo-5-[(4-sulfo-1-naphthyl)hydrazono]cyclohex-2-en-1-ylidene]hydrazino]naphthalene-1-sulfonic acid

The solubility of complex compounds such as 4-[2-[3-(hydroxymethyl)-4,6-dioxo-5-[(4-sulfo-1-naphthyl)hydrazono]cyclohex-2-en-1-ylidene]hydrazino]naphthalene-1-sulfonic acid can be influenced by several factors. Understanding its solubility characteristics is essential for its applications in various fields. Here are some considerations:

  • Polarity: This compound possesses multiple polar functional groups, including sulfonic acid and hydroxymethyl groups, which generally enhance its solubility in polar solvents like water.
  • pH Dependency: The solubility may change with pH levels, particularly because of the sulfonic acid group, which can dissociate to release protons, increasing solubility in acidic environments.
  • Temperature: As with many organic compounds, increased temperature can lead to higher solubility.
  • Solvent Interaction: The solvent choice can significantly affect solubility; for instance, organic solvents may yield different solubility profiles compared to aqueous solutions due to varying interactions.
  • Hydrogen Bonding: The presence of hydroxymethyl and sulfonic groups may facilitate hydrogen bonding with water molecules, aiding in its solubility.

In summary, while this compound is likely soluble in water due to its polar nature and functional groups, the exact solubility can vary based on the aforementioned factors. Investigating these properties can provide valuable insights for practical applications.

Interesting facts

Interesting Facts About 4-[2-[3-(hydroxymethyl)-4,6-dioxo-5-[(4-sulfo-1-naphthyl)hydrazono]cyclohex-2-en-1-ylidene]hydrazino]naphthalene-1-sulfonic acid

This complex compound is a member of the sulfonic acid family, which has drawn attention in the fields of organic chemistry and medicinal chemistry for its unique structural properties and potential applications.

  • Versatile Applications: The sulfonic acid group confers hydrophilicity to the compound, making it a potential candidate for various applications in drug formulation and as a dye.
  • Structure-Activity Relationship: The intricate arrangement involving multiple functional groups offers valuable insights into structure-activity relationships in organic molecules, providing a foundation for the development of new therapeutic agents.
  • Inhibition Studies: Some studies have suggested that derivatives of this compound can act as inhibitors in enzymatic processes, showcasing potential in the development of anticancer therapies.
  • Research Interest: The compound has attracted attention for its synthesis routes, particularly in the realm of catalytic reactions, where researchers explore innovative methods to create complex molecular architectures.

As a molecule embodying significant chemical complexity, 4-[2-[3-(hydroxymethyl)-4,6-dioxo-5-[(4-sulfo-1-naphthyl)hydrazono]cyclohex-2-en-1-ylidene]hydrazino]naphthalene-1-sulfonic acid serves as a fascinating subject for scientists and students alike. The study of such compounds not only broadens our understanding of chemical behavior but can also pave the way for breakthroughs in therapeutic development. As researchers delve deeper into its properties, they may uncover novel uses and applications that could have far-reaching implications in chemistry and medicine.

Synonyms
25738-39-0
DTXSID20859875
QYZJZOXEQZLXDY-UHFFFAOYSA-N
NS00048288
4,4'-{[2,4-Dihydroxy-5-(hydroxymethyl)-1,3-phenylene]bis(diazene-2,1-diyl)}di(naphthalene-1-sulfonic acid)