4-[2-(3-phenylisoxazol-5-yl)ethyl]morpholine

Identification

Molecular formula

C₁₅H₁₈N₂O₂

CAS number

136775-47-6

IUPAC name

4-[2-(3-phenylisoxazol-5-yl)ethyl]morpholine

State

The compound is in a solid state at room temperature.

Melting point (Celsius)

99.40

Melting point (Kelvin)

372.55

Boiling point (Celsius)

405.60

Boiling point (Kelvin)

678.75

General information

Molecular weight

270.31g/mol

Molar mass

270.3140g/mol

Density

1.2300g/cm³

Appearence

The compound is typically a crystalline solid, often appearing as white or off-white powder.

Comment on solubility

Solubility of 4-[2-(3-phenylisoxazol-5-yl)ethyl]morpholine

The solubility of the compound 4-[2-(3-phenylisoxazol-5-yl)ethyl]morpholine can be characterized by several important factors:

Polarity: Due to the presence of a morpholine ring and a phenylisoxazole moiety, this compound exhibits moderate polarity which can affect its solubility in various solvents.
Solvent Compatibility: Generally, it is expected to be soluble in:

Organic solvents like ethanol, methanol, and dimethyl sulfoxide (DMSO)
Less soluble in non-polar solvents such as hexane or pentane

Hydrogen Bonding: The ability for intermolecular hydrogen bonding due to the morpholine ring may enhance solubility in polar protic solvents.
Temperature Influence: Like many organic compounds, its solubility can increase with temperature; thus, elevated temperatures may help in achieving a clearer solution.

In summary, if you're working with 4-[2-(3-phenylisoxazol-5-yl)ethyl]morpholine, consider that it is likely to be more soluble in polar solvents and may present challenges in non-polar environments. Understanding these solubility characteristics is crucial for its application in various chemical processes.

Interesting facts

Interesting Facts about 4-[2-(3-phenylisoxazol-5-yl)ethyl]morpholine

4-[2-(3-phenylisoxazol-5-yl)ethyl]morpholine is a fascinating compound that captures the interest of many chemists due to its unique structure and potential applications. Here are some insights into this intriguing compound:

Structural Diversity: This compound features a morpholine ring, which is a six-membered ring containing both nitrogen and oxygen atoms. Morpholine derivatives are well-known in medicinal chemistry for their versatility.
Isoxazole Component: The presence of a phenylisoxazole moiety not only enhances its structural complexity but also contributes to its biological activity. Isoxazoles are often found in pharmaceuticals due to their ability to interact with various biological targets.
Potential Pharmacological Uses: Compounds similar to this one have shown promise in various therapeutic areas. Researchers are investigating their efficacy against neurological disorders, given the morpholine's ability to cross blood-brain barriers.
Research and Development: The synthesis of this compound provides a great opportunity for chemists to explore novel reactions and methods of functionalization, which might lead to new derivatives with enhanced properties.
Interdisciplinary Interest: The compound attracts attention from both organic chemists and pharmacologists, emphasizing the importance of collaboration across disciplines in the development of new drugs.

In summary, 4-[2-(3-phenylisoxazol-5-yl)ethyl]morpholine showcases the fascinating world of organic compounds, offering insights into chemical diversity and potential therapeutic applications. As stated by many in the field, "the exploration of new compounds is where innovation truly begins."