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Tamoxifen acetate

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Identification
Molecular formula
C31H29NO5
CAS number
10540-29-1
IUPAC name
[4-[2-(4-acetoxyphenyl)-1-ethylidene-but-2-enyl]phenyl] acetate
State
State

At room temperature, tamoxifen acetate is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
140.50
Melting point (Kelvin)
413.70
Boiling point (Celsius)
524.10
Boiling point (Kelvin)
797.30
General information
Molecular weight
563.64g/mol
Molar mass
563.6380g/mol
Density
1.0359g/cm3
Appearence

Tamoxifen acetate appears as a white to off-white crystalline powder. It is often provided in a pure or pharmaceutical-grade form for medical applications.

Comment on solubility

Solubility of [4-[2-(4-acetoxyphenyl)-1-ethylidene-but-2-enyl]phenyl] acetate

The solubility of [4-[2-(4-acetoxyphenyl)-1-ethylidene-but-2-enyl]phenyl] acetate can be a complex topic due to its large and intricate molecular structure. This compound belongs to the class of esters, which often exhibit varying solubility profiles based on their structural components.

Factors Influencing Solubility

Several factors can affect the solubility of this compound, including:

  • Polarity: The presence of the acetate group can enhance solubility in polar solvents, while large hydrophobic phenyl groups may decrease it.
  • Hydrogen Bonding: The capability of the compound to form hydrogen bonds can increase solubility, particularly in protic solvents.
  • Temperature: Like most organic compounds, solubility often increases with temperature due to enhanced molecular motion.
  • Solvent Type: It is expected to have higher solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) compared to water.

Expected Solubility Behavior

Based on structural analysis, one can hypothesize:

  • The compound is likely to be sparingly soluble in water due to its large non-polar segments.
  • In organic solvents, moderate to high solubility may be anticipated due to the favorable interactions between the solvent and the functional groups present.

As a rule of thumb, **"like dissolves like,"** thus recognizing that the solubility of [4-[2-(4-acetoxyphenyl)-1-ethylidene-but-2-enyl]phenyl] acetate will align with its polarity and the nature of the solvent utilized.

Interesting facts

Interesting Facts about [4-[2-(4-acetoxyphenyl)-1-ethylidene-but-2-enyl]phenyl] acetate

This compound, known as a derivative of phenyl acetate, is not just a simple substance but has intriguing characteristics and potential applications that make it a subject of interest in the field of organic chemistry. Here are some of the fascinating aspects of this compound:

  • Structure Complexity: The compound features multiple functional groups, notably the acetoxy and phenyl groups, which contribute to its unique chemical reactivity and molecular properties.
  • Potential Applications: Compounds like this often find applications in pharmaceuticals and material science due to their ability to participate in various chemical reactions, such as esterification and polymerization.
  • Synthetic Pathways: The synthesis of such a complex structure often involves multi-step synthetic pathways which require an understanding of different reactions and mechanisms that are foundational in organic chemistry.
  • Role of Stereochemistry: The presence of an ethenyl group in its structure implies that stereochemical considerations are vital, potentially impacting the compound's reactivity and interactions with biological entities.

In essence, [4-[2-(4-acetoxyphenyl)-1-ethylidene-but-2-enyl]phenyl] acetate serves as a reminder of the beauty and complexity of organic molecules, where small changes in molecular structure can lead to vastly different chemical behaviors and properties. As we delve deeper into the world of organic compounds, understanding such derivatives becomes crucial in advancing fields such as drug development and materials engineering.

Synonyms
DIENESTROL DIACETATE
84-19-5
3,4-Bis(4-acetoxyphenyl)-2,4-hexadiene
4-{4-[4-(acetyloxy)phenyl]hexa-2,4-dien-3-yl}phenyl acetate
AKOS024319054
DB-252050
4-{2-[4-(acetyloxy)phenyl]-1-ethylidene-2-butenyl}phenyl acetate