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4,4'-Methylenedianiline

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Identification
Molecular formula
C13H14N2
CAS number
101-77-9
IUPAC name
4-[2-(4-aminophenyl)ethyl]aniline
State
State

At room temperature, 4,4'-Methylenedianiline is typically found as a solid. This can be in the form of crystals, a powder, or flakes.

Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
398.00
Boiling point (Kelvin)
671.15
General information
Molecular weight
198.27g/mol
Molar mass
198.2650g/mol
Density
1.1920g/cm3
Appearence

4,4'-Methylenedianiline appears as a white to light tan crystalline solid. The compound may also appear in the form of flakes or a powder. Due to impurities, slight variations in the shade can occur, lending it a more off-white to tan color. The substance may emit an amine-like odor.

Comment on solubility

Solubility of 4-[2-(4-aminophenyl)ethyl]aniline

The solubility of 4-[2-(4-aminophenyl)ethyl]aniline can be influenced by several factors, including its molecular structure and the solvent used. This compound exhibits some distinctive characteristics regarding its solubility:

  • Solvent Polarity: It is typically more soluble in polar solvents such as water or ethanol rather than in non-polar solvents like hexane. This is due to the presence of the amino groups which can form hydrogen bonds with polar solvents.
  • Temperature Dependency: As with many organic compounds, 4-[2-(4-aminophenyl)ethyl]aniline's solubility generally increases with temperature. Higher temperatures often help in overcoming the lattice energy of the compound.
  • pH Influence: The solubility may also vary with the pH of the solution. Under acidic conditions, the amino groups can become protonated, enhancing solubility in aqueous solutions.

In summary, while the solubility of 4-[2-(4-aminophenyl)ethyl]aniline in water may be limited, it can exhibit greater solubility in slightly acidic or polar organic solvents. As a reminder, “solubility is about finding the right match” between the compound and the solvent to maximize interaction and dissolution.

Interesting facts

Interesting Facts about 4-[2-(4-aminophenyl)ethyl]aniline

4-[2-(4-aminophenyl)ethyl]aniline, commonly recognized for its intriguing structure, is a compound that draws attention in the fields of organic chemistry and pharmaceuticals. Below are some compelling aspects of this dual-function compound:

  • Chemical Structure: The compound features an aniline moiety, which is a primary aromatic amine. This functional group plays a crucial role in the reactivity and properties of the compound.
  • Biological Significance: This compound is of interest in medicinal chemistry, particularly due to its potential use in synthesizing pharmaceuticals aimed at treating various medical conditions.
  • Versatile Precursor: The structure of 4-[2-(4-aminophenyl)ethyl]aniline allows it to act as a versatile building block for more complex molecules, making it valuable in organic synthesis.
  • Research Applications: Due to its unique properties and structure, it is often studied in research settings to understand its interactions with biological systems and its potential efficacy as a drug candidate.
  • Safety and Handling: As with many aniline derivatives, safety precautions must be taken during handling, as they may pose risks including toxicity.

In conclusion, 4-[2-(4-aminophenyl)ethyl]aniline illustrates the fascinating intersection of chemistry and biology. Its significant role in research and development highlights the importance of understanding the nuanced properties of organic compounds.

Synonyms
4,4'-Ethylenedianiline
621-95-4
4,4'-Diaminodibenzyl
Benzenamine, 4,4'-(1,2-ethanediyl)bis-
CCRIS 1004
EINECS 210-716-7
BRN 0394999
4,4-Ethylenedianiline
DTXSID3060742
EC 210-716-7
4-13-00-00401 (Beilstein Handbook Reference)
DTXCID3043237
210-716-7
uhnuhzhqlcgzda-uhfffaoysa-n
4,4'-Diaminobibenzyl
4-[2-(4-aminophenyl)ethyl]aniline
4,4'-(ethane-1,2-diyl)dianiline
4,4'-Ethylenebis(aniline)
1,2-Bis(p-aminophenyl)ethane
alpha,alpha'-Bi-p-toluidine
Aniline, 4,4'-ethylenedi-
NSC 580
.alpha.,.alpha.'-Bi-p-toluidine
NSC 44062
NSC 60033
ANILINE, p,p'-ETHYLENEDI-
4-[2-(4-Aminophenyl)ethyl]phenylamine
1,2-Bis(4-Aminophenyl)ethane
4,4'-ethane-1,2-diyldianiline
NSC-580
NSC-44062
NSC-60033
Aniline,4'-ethylenedi-
Benzenamine,4'-(1,2-ethanediyl)bis-
MFCD00007923
a,a'-Bi-p-toluidine
4,4\'-Ethylenedianiline
alpha, alpha-Bi-p-toluidine
Oprea1_504832
CBDivE_013839
MLS001180989
SCHEMBL187043
NSC580
S78Y4P4C7L
CHEMBL1704183
HMS2804F06
4,4'-Diamino-1,2-diphenylethane
ALBB-021248
NSC44062
NSC60033
STL089722
AKOS000120248
4,4'-(1,2-Ethanediyl)bis[benzenamine]
AC-16755
AS-60549
SMR000476340
4-[2-(4-Aminophenyl)ethyl]phenylamine #
DB-054089
CS-0089167
E0346
NS00003339
EN300-18238
F16584
4,4'-Ethylenedianiline, technical, >=95% (NT)
AH-034/32835045
Z256707848