Interesting facts
Interesting Facts about 4-[2-(5-Nitroimidazol-1-yl)ethyl]morpholine
4-[2-(5-Nitroimidazol-1-yl)ethyl]morpholine is a fascinating compound with a unique structure and significant biological activity. Here are some intriguing aspects:
- Antimicrobial Activity: This compound is primarily known for its role as an antimicrobial agent, particularly against anaerobic bacteria. Its effectiveness makes it a valuable component in treatments for infections caused by such organisms.
- Mechanism of Action: The 5-nitroimidazole moiety is crucial for its action. Compounds in this family usually undergo reduction in the bacterial cell, leading to the formation of reactive intermediates that disrupt DNA synthesis.
- Pharmaceutical Significance: As a derivative of morpholine, this compound combines the properties of its parent structure with those of nitroimidazoles, leading to innovative approaches in drug design, especially in the treatment of resistant strains.
- Research Applications: Beyond its clinical uses, 4-[2-(5-Nitroimidazol-1-yl)ethyl]morpholine has been the subject of extensive research investigating its potential in various pharmacological applications, including oncology and antiparasitic treatments.
- Structural Characteristics: The presence of both the morpholine ring and the nitroimidazole group contributes to its solubility in different environments, enhancing its bioavailability and effectiveness.
This compound exemplifies the intersection of medicinal chemistry and pharmacology, showcasing how small modifications in molecular structure can lead to significant improvements in biological activity. As research continues to unfold, 4-[2-(5-Nitroimidazol-1-yl)ethyl]morpholine is likely to remain a compound of interest for scientists dedicated to overcoming microbial resistance and improving therapeutic options.
Synonyms
Nimorazole
6506-37-2
Naxogin
Nitrimidazine
Nimorazol
Nulogyl
Esclama
Naxofem
4-(2-(5-Nitro-1H-imidazol-1-yl)ethyl)morpholine
Acterol
Acterol forte
Nimorazolo
Sirledi
Nimorazolum
4-[2-(5-Nitroimidazol-1-yl)ethyl]morpholine
K-1900
Nimorazolo [DCIT]
N-2-Morpholinoethyl-5-nitroimidazole
1-(2-N-Morpholinylethyl)-5-nitroimidazole
Nimorazol [INN-Spanish]
Nimorazolum [INN-Latin]
Morpholine, 4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]-
NSC 107524
Nimorazole [INN:BAN]
1-(N-p-Ethylmorpholine)-5-nitroimidazole
1-(beta-Morpholinoethyl)-5-nitroimidazole
EINECS 229-394-4
UNII-469ULX0H4G
Nimorazole (INN)
4-(2-(5-Nitroimidazol-1-yl)ethyl)morpholine
Naxogin (TN)
4-(2-(5-Nitroimidazol-1-yl)ethyl)-morpholine
NSC-107524
BRN 0533758
469ULX0H4G
4-[2-(5-Nitro-1H-imidazol-1-yl)ethyl]morpholine
DTXSID1057795
Morpholine, 4-(2-(5-nitro-1H-imidazol-1-yl)ethyl)-
NIMORAZOLE [MI]
NIMORAZOLE [INN]
Morpholine, 4-(2-(5-nitroimidazol-1-yl)ethyl)-
NIMORAZOLE [MART.]
NIMORAZOLE [WHO-DD]
1-(.beta.-Morpholinoethyl)-5-nitroimidazole
DTXCID2031584
Nimorazol (INN-Spanish)
Nimorazolum (INN-Latin)
NIMORAZOLE (MART.)
Morpholine, 4-[2-(5-nitroimidazol-1-yl)ethyl]-
Naxogin 500
P01AB06
Morpholine, 4-(2-(5-nitro-1H-imidazol-1-yl)ethyl)-(9CI)
229-394-4
mdjfhrltprpzly-uhfffaoysa-n
MLS002703984
K 1900
Nimorazole?
MFCD00866796
Nimorazole (Standard)
SCHEMBL21836
CHEMBL435966
CHEBI:134929
GLXC-05724
BCP11055
GAA50637
Tox21_113897
HY-16349R
NSC107524
s6411
AKOS022174968
DB12172
NCGC00261977-01
AC-35227
AS-31120
DA-21636
HY-16349
SMR001570693
CAS-6506-37-2
WLN: T6N DOTJ A2- AT5N CNJ ENW
NS00006047
D07352
Q7037737
4-[2-(5-Nitro-1H-imidazol-1-yl)ethyl]morpholine #
BRD-K79145628-001-05-5
Solubility of 4-[2-(5-nitroimidazol-1-yl)ethyl]morpholine
The solubility of 4-[2-(5-nitroimidazol-1-yl)ethyl]morpholine can be characterized by several key factors, making it an interesting compound in terms of its interaction with solvents. Primarily, this compound is known to exhibit significant solubility in polar solvents, which can be attributed to the presence of both the morpholine ring and the nitro-substituted imidazole moiety. This combination creates a balance between the hydrophilic and lipophilic characteristics of the molecule.
Several points that highlight the solubility characteristics include:
In summary, 4-[2-(5-nitroimidazol-1-yl)ethyl]morpholine demonstrates a remarkable solubility profile in polar environments, influenced by structural features and external conditions, making it a versatile compound for various applications.