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Cefalexin

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Identification
Molecular formula
C16H17N3O4S
CAS number
15686-71-2
IUPAC name
4-[(2-acetamido-3-carboxy-propanoyl)amino]-5-[[1-[[1-(carboxymethyl)-2-(4-nitroanilino)-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]amino]-5-oxo-pentanoic acid
State
State

At room temperature, cefalexin is typically in a solid state. It is crucial to maintain it in a dry and cool environment to preserve its stability and effectiveness for pharmaceutical applications.

Melting point (Celsius)
203.50
Melting point (Kelvin)
476.60
Boiling point (Celsius)
396.20
Boiling point (Kelvin)
669.20
General information
Molecular weight
347.39g/mol
Molar mass
347.3890g/mol
Density
1.3479g/cm3
Appearence

Cefalexin appears as a white to almost white crystalline powder. It is practically insoluble in water and slightly soluble in alcohol. This compound is an antibiotic belonging to the cephalosporin class, and it is typically formulated in tablets or capsules for medical use.

Comment on solubility

Solubility Characteristics of 4-[(2-acetamido-3-carboxy-propanoyl)amino]-5-[[1-[[1-(carboxymethyl)-2-(4-nitroanilino)-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]amino]-5-oxo-pentanoic acid

The compound 4-[(2-acetamido-3-carboxy-propanoyl)amino]-5-[[1-[[1-(carboxymethyl)-2-(4-nitroanilino)-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]amino]-5-oxo-pentanoic acid (C16H17N3O4S) showcases notable solubility characteristics indicative of its complex molecular structure.

Factors Influencing Solubility

Several factors contribute to the solubility of this compound:

  • Polar Functional Groups: The presence of multiple carboxyl (-COOH), amino (-NH2), and acetamido groups enhances its ability to interact with polar solvents like water.
  • Molecular Weight: With a relatively high molecular weight, solubility may be limited in non-polar solvents.
  • Ionic Nature: The compound’s ionic characteristics allow it to dissolve better in aqueous solutions, particularly at varying pH levels.

Expected Solubility

Overall, it is anticipated that:

  • The compound is likely to be soluble in water due to its polar functional groups and ionic interactions.
  • Solubility may decrease in non-polar solvents like hexane or toluene.

As a result, when investigating its applications, one should consider its solubility profile, as “solubility is key to the bioavailability and efficacy of many therapeutic agents.”

Interesting facts

Interesting Facts about 4-[(2-acetamido-3-carboxy-propanoyl)amino]-5-[[1-[[1-(carboxymethyl)-2-(4-nitroanilino)-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]amino]-5-oxo-pentanoic acid

This compound, with its complex and lengthy name, showcases the fascinating world of amino acids and peptides. It highlights the intricate chemistry involved in biological processes, especially in the realm of drug design. Here are some intriguing facts about it:

  • Biological Relevance: This compound is representative of a class of molecules involved in various biochemical pathways, making it significant in medicinal chemistry and pharmaceutical applications.
  • Functional Groups: It contains multiple functional groups such as amides, carboxylic acids, and nitro groups, which can be crucial for biochemical interactions and reactivity.
  • Potential Applications: Due to its structure, this compound could serve as a scaffold for developing novel therapeutic agents, particularly in the field of targeted drug delivery or cancer treatment.
  • Quantifying Activity: The presence of various reactive sites gives chemists the ability to modify and quantify biological activity, potentially leading to more effective treatments with fewer side effects.
  • In Silico Studies: Researchers often use computational modeling to predict how compounds like this interact with biological targets, allowing for a more efficient drug discovery process.

As chemists delve into the structure and properties of compounds like this one, they constantly gain insights that could revolutionize medicine and improve health outcomes. The interplay of chemistry and biology makes this field an exciting frontier for scientific inquiry.

Synonyms
Ac-DEVD-pNA
189950-66-1
Caspase-3 substrate (chromogenic)
FA110798
DB-044722