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Epinephrine

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Identification
Molecular formula
C9H13NO3
CAS number
51-43-4
IUPAC name
4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol
State
State
At room temperature, epinephrine typically exists as a solid in its pure form. When processed for medical use, it is often encountered as a solution with its salts, making it appear liquid under those conditions.
Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
246.15
Boiling point (Kelvin)
519.30
General information
Molecular weight
183.20g/mol
Molar mass
183.2040g/mol
Density
1.2830g/cm3
Appearence

Epinephrine is a white to off-white crystalline powder. It may appear in the form of its hydrochloride or other salts, which can affect its precise appearance but it is generally known for its crystalline nature when pure.

Comment on solubility

Solubility of 4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol

The compound 4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol, with the formula C9H13NO3, exhibits interesting solubility properties that are influenced by its molecular structure.

Factors Affecting Solubility

Several factors contribute to the solubility characteristics of this compound:

  • Hydroxyl Groups: The presence of hydroxyl (-OH) groups can enhance solubility in polar solvents, especially water, due to the ability to form hydrogen bonds.
  • Amino Group: The amino (-NH2) group further increases polarity, promoting solubility in aqueous environments.
  • Hydrophobic Ring System: The benzene ring introduces a hydrophobic character, which can limit solubility in very polar solvents but may enhance solubility in organic solvents.

Predicted Solubility

Based on these factors, it can be predicted that the solubility of this compound is:

  • Moderate to High in water due to the combination of polar functional groups.
  • Higher in organic solvents like ethanol or acetone where the hydrophobic benzene portion can interact more favorably.

In summary, the solubility of 4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol is primarily dictated by its functional groups. As stated, "the balance of hydrophilic and hydrophobic characteristics defines the compound's solubility behavior". Hence, understanding these characteristics not only aids in predicting its solubility but also plays a crucial role in its practical applications in various chemical environments.

Interesting facts

Interesting Facts About 4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol

4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol, also known as a derivative of catecholamine, holds a fascinating place in the world of chemistry due to its unique structural features and potential biological activities.

Biological Significance

This compound is of particular interest in the fields of biochemistry and pharmacology because:

  • It acts as a precursor for the synthesis of neurotransmitters, playing a crucial role in the central nervous system.
  • Its amino group is known to participate in various biochemical reactions, making it a valuable building block for medicinal chemistry.
  • The hydroxy groups can form hydrogen bonds, contributing to interactions with biological macromolecules like proteins and nucleic acids.

Applications in Research

Researchers have shown keen interest in this compound for several reasons:

  • It can be used in studies of oxidative stress due to its ability to undergo redox reactions.
  • The compound’s role in various signaling pathways is under investigation, where it helps elucidate mechanisms involved in cell function and disease.
  • As a potential antioxidant, it is being explored for its ability to mitigate damage caused by free radicals in living organisms.

Structural Features

The structural complexity of 4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol allows for:

  • Substitution reactions that can yield a variety of analogs for use in pharmaceutical development.
  • Intermolecular interactions, enhancing its solubility in various solvents and its reactivity.

In conclusion, 4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol serves as a prime example of how organic compounds can bridge the gap between chemistry and life sciences, showcasing the intricate relationships that govern molecular behavior and biological activity. As science progresses, the potential applications and implications of this compound will continue to be a source of exploration and discovery.

Synonyms
138-65-8
dl-Noradrenaline
dl-Norepinephrine
4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
dl-Arterenol
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-
(+/-)-noradrenaline
NSC 294898
Norepinephrine, DL-
Levarterenol;L-Noradrenaline
[3H]NE
K294OAI79V
CHEBI:33569
NSC294898
NSC-294898
Noradrenalin, dl-
(+-)-Noradrenaline
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (.+/-.)-
586-17-4
EINECS 205-337-9
UNII-K294OAI79V
Noradrop
MFCD00025592
xi-Norepinephrine
Noradrenaline,(+)
(+/-)-norepinephrine
(.+-.)-Noradrenaline
(.+/-.)-Arterenol
(.+-.)-Norepinephrine
(1)-4-(2-Amino-1-hydroxyethyl)pyrocatechol
DL-[7-3H]norepinephrine
(.+/-.)-Noradrenaline
CHEMBL432
(.+/-.)-Norepinephrine
WLN: Z1YQR CQ DQ
SCHEMBL2610
NORADRENALINE DL FORM
GTPL484
BDBM35234
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (+-)-
DTXSID20858964
NORADRENALINE, (+/-)-
AAA13865
BCP04227
NOREPINEPHRINE DL-FORM [MI]
1, 4-(2-amino-1-hydroxyethyl)-
BENZYL ALCOHOL, alpha-(AMINOMETHYL)-3,4-DIHYDROXY-, (+-)-
PDSP1_001514
PDSP2_001498
AKOS000123495
AKOS022180874
CCG-204148
HR-0338
SDCCGSBI-0050041.P003
NCGC00185992-01
NCGC00185992-02
1-(3,4-Dihydroxy)phenyl-2-aminoethanol
AC-10030
Benzyl alcohol,4-dihydroxy-, (.+-.)-
NS00078990
4-(2-amino-1-hydroxy-ethyl)benzene-1,2-diol
EN300-245335
G77791
1, 4-(2-amino-1-hydroxyethyl)-, (.+-.)-
4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol #
L000933
SR-01000075279-3
4-[(1rs)-2-amino-1-hydroxyethyl]-1,2-benzenediol
benzene, 1-(2-amino-1-hydroxy)ethyl-3,4-dihydroxy-
Q27087994
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (dl)-
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (RS)-
1,2-BENZENEDIOL, 4-(2-AMINO-1-HYDROXYETHYL)-, (+/-)-
Benzyl alcohol, .alpha.-(aminomethyl)-3,4-dihydroxy-, (.+/-.)-
DL-Arterenol, dl-Norepinephrine, EINECS 205-337-9, (+/-)-Noradrenaline
104655-07-4
622-681-9