Skip to main content

Chlorambucil

ADVERTISEMENT
Identification
Molecular formula
C14H19Cl2NO2.HCl
CAS number
305-03-3
IUPAC name
[4-[(2-aminoacetyl)amino]phenyl]-bis(2-chloroethyl)ammonium;chloride
State
State
Chlorambucil is typically a solid at room temperature. Due to its crystalline structure, it does not flow like liquids or gases and requires careful handling, especially since it's used in a clinical setting.
Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
304.20g/mol
Molar mass
304.1950g/mol
Density
1.3350g/cm3
Appearence
Chlorambucil appears as a yellowish crystalline powder. It is hygroscopic, meaning it can absorb moisture from the environment, which necessitates careful storage conditions.
Comment on solubility

Solubility of [4-[(2-aminoacetyl)amino]phenyl]-bis(2-chloroethyl)ammonium;chloride

The solubility of the compound [4-[(2-aminoacetyl)amino]phenyl]-bis(2-chloroethyl)ammonium;chloride is an intriguing topic due to its unique structural properties. This compound contains both an amino group and a quaternary ammonium group, which significantly affects its interaction with solvents.

Several key points regarding its solubility include:

  • Polar Nature: The presence of chlorides and amine functional groups indicates that the compound is likely to be polar, making it more soluble in polar solvents such as water.
  • Hydrogen Bonding: The amino groups can participate in hydrogen bonding, which further enhances solubility in polar solvents.
  • Low Solubility in Nonpolar Solvents: Conversely, the compound is expected to have low solubility in nonpolar solvents due to its polar characteristics.

In conclusion, understanding the solubility of this compound is crucial for its application in various fields. The balance between its polar functionalities and the overall molecular structure dictates its solubility behavior, paving the way for interactions in biological and chemical processes.

Interesting facts

Interesting Facts about 4-[(2-aminoacetyl)amino]phenyl-bis(2-chloroethyl)ammonium;chloride

This compound, often referred to in research contexts, showcases the fascinating interplay between organic chemistry and medicinal applications. Here are some intriguing aspects worth noting:

  • Structural Complexity: Featuring a phenyl ring substituted with amino groups and bis(2-chloroethyl) substituents, this compound exemplifies how structural modifications can influence biological activity.
  • Potential Anticancer Properties: Compounds containing chloroethyl groups are known for their role in alkylating agents, which are often used in chemotherapy. This compound's structure suggests potential for similar therapeutic applications.
  • Role of Amino Acids: With the presence of aminoacetyl groups, this compound highlights the importance of amino acids in drug design, as they can modulate the interaction with biological targets.
  • Research Interest: Due to its unique function and structure, this compound has piqued the interest of researchers exploring innovative therapies for various diseases.

As noted by chemists in the field, "Understanding the nuances of compound interactions can lead to breakthroughs in treatment methodologies." This compound serves as a testament to that notion, illustrating how even subtle structural elements can dramatically impact clinical efficacy.

In summary, 4-[(2-aminoacetyl)amino]phenyl-bis(2-chloroethyl)ammonium;chloride stands as a significant subject of study not just for its chemical properties but for its potential contributions to modern medicine and therapeutic strategies.

Synonyms
2-Amino-4'-(bis(2-chloroethyl)amino)acetanilide hydrochloride
3131-20-2
ACETANILIDE, 2-AMINO-4'-(BIS(2-CHLOROETHYL)AMINO)-, MONOHYDROCHLORIDE