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Fosamprenavir

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Identification
Molecular formula
C25H36N3O9P
CAS number
226700-79-4
IUPAC name
4-(2-aminoethoxy)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)-4-pyridyl]methylamino]but-3-enoic acid
State
State

At room temperature, Fosamprenavir is in a solid state, typically found in the form of a crystalline powder.

Melting point (Celsius)
154.50
Melting point (Kelvin)
427.65
Boiling point (Celsius)
310.20
Boiling point (Kelvin)
583.35
General information
Molecular weight
586.62g/mol
Molar mass
586.6220g/mol
Density
1.5649g/cm3
Appearence

Fosamprenavir is typically found as a white to off-white crystalline powder. Its appearance may vary slightly depending on the degree of hydration and specific formulation.

Comment on solubility

Solubility of 4-(2-aminoethoxy)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)-4-pyridyl]methylamino]but-3-enoic acid (C25H36N3O9P)

This compound exhibits notable solubility characteristics primarily influenced by its complex structure and the presence of various functional groups that interact with solvents. Here are some key points regarding its solubility:

  • Polarity: The molecule contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions, which can lead to variable solubility in different solvents.
  • Amino Groups: The presence of amino groups typically enhances solubility in polar solvents such as water due to their ability to form hydrogen bonds.
  • Phosphonic Acid Moiety: The phosphono group also contributes to increased solubility in aqueous environments, as it can ionize, further interacting with water and enhancing overall solubility.
  • Hydroxyl Group: The hydroxy group in the molecule promotes solubility in polar solvents due to its capacity for hydrogen bonding.

Overall, while the compound may show appreciable solubility in polar solvents like water or methanol, it might exhibit lower solubility in non-polar solvents. Thus, the detailed solubility profile should be experimentally determined under various conditions to completely understand its behavior in different media.


Interesting facts

Interesting Facts About 4-(2-aminoethoxy)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)-4-pyridyl]methylamino]but-3-enoic acid

This compound is quite fascinating due to its complex structure and potentially significant biological applications. Here are some noteworthy details:

  • Multifunctionality: The compound contains several functional groups, making it a potentially multifunctional agent, suitable for various applications in medicinal chemistry.
  • Pyridine Derivatives: The presence of a pyridine ring indicates its potential role in pharmacology, as many drug molecules incorporate heterocyclic systems for improved bioactivity.
  • Phosphonate Group: The phosphono group suggests that it might have properties akin to phosphonic acid compounds, which are often important in the development of herbicides and pharmaceuticals.
  • Amino Group: The amino group not only enhances solubility in biological environments but also suggests possible interactions with biological targets through hydrogen bonding.
  • Structural Diversity: This compound exhibits structural diversity due to its multiple substituents, making it an interesting subject for structure-activity relationship (SAR) studies.

As a scientist, one cannot help but marvel at how the intricate interplay of its components could lead to innovative therapies. Such compounds often serve as a reminder of the importance of chemical diversity in the development of new drugs, leading to advancements in the field of pharmacology and therapeutic interventions.

Further research into this compound may unveil substantial benefits, especially in the treatment of various diseases, paving the way for novel therapeutic strategies.