Skip to main content

Chlormethine Hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C12H16Cl3N3O2
CAS number
55-86-7
IUPAC name
[4-(2-azaniumyl-2-carboxy-ethyl)phenyl]methyl-bis(2-chloroethyl)ammonium;dichloride
State
State

At room temperature, chlormethine hydrochloride is a solid. It requires proper storage conditions to ensure stability, typically in a cool and dry place to prevent degradation.

Melting point (Celsius)
37.50
Melting point (Kelvin)
310.65
Boiling point (Celsius)
267.00
Boiling point (Kelvin)
540.15
General information
Molecular weight
304.21g/mol
Molar mass
304.2080g/mol
Density
1.4000g/cm3
Appearence

Chlormethine hydrochloride appears as an off-white to yellowish powder. It is hygroscopic in nature, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of [4-(2-azaniumyl-2-carboxy-ethyl)phenyl]methyl-bis(2-chloroethyl)ammonium;dichloride

The solubility of the compound [4-(2-azaniumyl-2-carboxy-ethyl)phenyl]methyl-bis(2-chloroethyl)ammonium;dichloride can be influenced by several key factors:

  • Polar Nature: Being a quaternary ammonium salt, it exhibits significant polarity due to the presence of +NH and -COO functional groups, which enhances its solubility in polar solvents such as water.
  • Hydrogen Bonding: The carboxylic acid group can engage in hydrogen bonding, further contributing to solubility.
  • Hydrophilicity: The compound has hydrophilic characteristics, thanks to its ionic components, promoting its dissolution in aqueous mediums.

In general, quaternary ammonium salts are known for their favorable solubility profiles in water. However, solubility can vary significantly with:

  1. Temperature: Higher temperatures typically increase solubility.
  2. pH levels: Changes in the pH can affect the ionization state of the compound.
  3. Presence of Organic Solvents: Solubility may decrease in non-polar solvents due to reduced interaction with the ionic groups.

In summary, [4-(2-azaniumyl-2-carboxy-ethyl)phenyl]methyl-bis(2-chloroethyl)ammonium;dichloride is expected to be soluble in polar solvents, particularly water, while its solubility can be affected by temperature and solvent composition.

Interesting facts

Interesting Facts about [4-(2-azaniumyl-2-carboxy-ethyl)phenyl]methyl-bis(2-chloroethyl)ammonium; dichloride

This compound is a fascinating example of a quaternary ammonium compound, known for its unique structural features and potential applications. Here are some intriguing facts:

  • Functional Diversity: The presence of two distinct functional groups, the ammonium and carboxylic acid, allows this compound to exhibit both ionic and hydrogen bonding interactions, making it versatile in various chemical environments.
  • Biomedical Applications: Quaternary ammonium compounds are often explored for their antimicrobial properties. This particular compound may harbor potential as an antibacterial or antifungal agent due to its positively charged ammonium group, which can disrupt microbial membranes.
  • Research Potential: The unique structure of this compound may also suggest applications in drug delivery systems, particularly in targeting specific cells. The carboxylic group might enhance solubility and bioavailability, making it of interest in pharmaceutical formulations.
  • Environmental Impact: As with many chemical compounds, understanding both the synthesis and degradation pathways is crucial. Researchers are increasingly focused on the environmental footprint of quaternary ammonium compounds since they can accumulate in ecosystems.
  • Structure-Activity Relationship: Studying the relationship between the compound's structure and its activity can provide insights into designing even more effective derivatives. Scientists often modify the chlorinated alkyl groups to optimize performance in various applications.

In summary, [4-(2-azaniumyl-2-carboxy-ethyl)phenyl]methyl-bis(2-chloroethyl)ammonium; dichloride is not just a complex name but a compound brimming with promise and opportunities for further exploration in chemistry, pharmacology, and environmental science.

Synonyms
p-Bis(2-chloroethyl)aminomethyl-phenylalanine dihydrochloride
ALANINE, 3-(p((BIS(2-CHLOROETHYL)AMINO)METHYL)PHENYL)-, DIHYDROCHLORIDE
2185-97-9