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Flephedrone

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Identification
Molecular formula
C16H21FNO
CAS number
871217-01-7
IUPAC name
4-(2-azaspiro[4.6]undecan-2-yl)-1-(4-fluorophenyl)butan-1-one
State
State

At room temperature, flephedrone is generally encountered as a solid in the form of powder or crystal.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
247.34g/mol
Molar mass
247.3200g/mol
Density
1.1800g/cm3
Appearence

Flephedrone is typically found as a white crystalline powder. As with many synthetic cathinones, it may also appear as fine granules or crystals. The texture can vary depending on the specific synthetic process and any cuts or adulterants present in non-pure forms.

Comment on solubility

Solubility of 4-(2-azaspiro[4.6]undecan-2-yl)-1-(4-fluorophenyl)butan-1-one

The solubility of 4-(2-azaspiro[4.6]undecan-2-yl)-1-(4-fluorophenyl)butan-1-one can be influenced by various factors, including its structure and chemical properties. This compound presents an interesting profile due to its specific molecular architecture:

  • Polar and Nonpolar Regions: The presence of both polar (amine and carbonyl) and nonpolar elements (alkyl and aromatic components) suggests that solubility may vary in different solvent environments.
  • Solvent Compatibility: It's likely to show better solubility in polar organic solvents such as alcohols or dimethyl sulfoxide (DMSO), whereas it may have limited solubility in nonpolar solvents due to its polar moieties.
  • Hydrogen Bonding: The amine group can engage in hydrogen bonding, enhancing solubility in polar solvents and possibly stabilizing interactions with solvent molecules.

In general, expected solubility patterns could align with the notion that:

  1. In polar solvents: Enhanced solubility due to hydrogen bonding and dipole interaction.
  2. In nonpolar solvents: Reduced solubility due to the absence of attractive forces.

Thus, understanding the compound's solubility characteristics requires a careful consideration of its molecular structure and the nature of the solvent. Awareness of these factors can enable better predictions regarding its behavior in various chemical environments.

Interesting facts

Interesting Facts about 4-(2-azaspiro[4.6]undecan-2-yl)-1-(4-fluorophenyl)butan-1-one

This fascinating compound is part of the class of chemicals known as ketones, and it exhibits unique properties that make it a subject of interest in various fields, particularly medicinal chemistry. Here are some intriguing aspects:

  • Molecular Structure: The presence of the azaspiro moiety in its structure adds complexity and may contribute to interesting biological activities. Spiro compounds often exhibit unique three-dimensional geometries that can significantly impact their interaction with biological targets.
  • Fluorine Substitution: The incorporation of a fluorine atom in the phenyl ring (4-fluorophenyl) enhances both the lipophilicity and the metabolic stability of the compound. This modification often improves binding affinity to various receptors and enzymes in biological systems.
  • Potential Applications: Compounds with similar structures have shown promise in drug development, particularly in the areas of neurological and psychiatric disorders. For instance, the spiro structure is often associated with neuroactive compounds.
  • Research Focus: Studies utilizing compounds like this one may include investigations into their effects on neurotransmitter systems, offering potential insights into treatments for conditions such as depression or anxiety.
  • Design and Synthetic Chemistry: The synthesis of such a compound often involves multi-step reactions, showcasing the ingenuity of organic chemistry. The development of efficient synthetic pathways for producing complex molecules is critical in pharmaceutical research.

As scientists continue to explore the vast potential of such compounds, their unique structures may lead to the discovery of new therapeutic agents that could transform our understanding and treatment of various health conditions.

In conclusion, 4-(2-azaspiro[4.6]undecan-2-yl)-1-(4-fluorophenyl)butan-1-one represents an intriguing intersection of structure and function, proving that even complex organic molecules can have significant implications in real-world applications.

Synonyms
BRN 1431874
BUTYROPHENONE, 4-(2-AZASPIRO(4.6)UNDEC-2-YL)-4'-FLUORO-
4-(2-Azaspiro(4.6)undec-2-yl)-4'-fluoro-butyrophenone
1235-67-2
DTXSID80154030
DTXCID7076521