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Diphenhydramine Hydrochloride

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Identification
Molecular formula
C17H21NO · HCl
CAS number
147-24-0
IUPAC name
4-(2-benzhydryloxyethyl)morpholine;hydrochloride
State
State

At room temperature, diphenhydramine hydrochloride is generally found in a solid state as a stable salt form. It is water-soluble and is typically administered in solid forms such as tablets or capsules, though it may also be found in liquid solutions for medicinal uses.

Melting point (Celsius)
168.50
Melting point (Kelvin)
441.70
Boiling point (Celsius)
353.20
Boiling point (Kelvin)
626.35
General information
Molecular weight
291.82g/mol
Molar mass
291.8140g/mol
Density
1.1257g/cm3
Appearence

Diphenhydramine hydrochloride is a white or slightly creamy powder. It is free flowing and can appear as crystalline in nature.

Comment on solubility

Solubility of 4-(2-benzhydryloxyethyl)morpholine;hydrochloride

The solubility of 4-(2-benzhydryloxyethyl)morpholine; hydrochloride can be quite interesting due to its unique chemical structure. As a hydrochloride salt, this compound tends to exhibit some specific solubility characteristics:

  • High Solubility in Water: Being a salt, it is generally soluble in water, which allows for effective dissolution and availability in aqueous environments.
  • Influence of pH: The solubility may also be affected by the pH of the solution. In more acidic conditions, the compound may have increased solubility.
  • Temperature Dependency: Like many compounds, solubility often increases with temperature, making higher temperatures favorable for achieving a more concentrated solution.

In practice, the solubility of 4-(2-benzhydryloxyethyl)morpholine; hydrochloride is an essential factor to consider for applications in formulation science, pharmacology, and organic synthesis. It is important to conduct experiments to determine the exact solubility limits in various solvents to optimize utilization and effectiveness in specific applications.

In summary, key aspects to remember include:

  • Soluble in water
  • Affected by pH levels
  • Increased solubility with rising temperature

This intricate interplay of factors makes understanding its solubility essential for researchers and practitioners working with this compound.

Interesting facts

Interesting Facts about 4-(2-benzhydryloxyethyl)morpholine; hydrochloride

4-(2-benzhydryloxyethyl)morpholine; hydrochloride is a fascinating compound that belongs to the category of morpholine derivatives. These compounds are notable for their relevance in medicinal chemistry and drug development. Here are some intriguing aspects of this compound:

  • Structure and Function: The unique architecture of this compound includes a morpholine ring and a benzhydryloxyethyl side chain. This combination allows for diverse interactions with biological targets.
  • Pharmacological Activities: Morpholine derivatives have been studied for various pharmacological activities, including antidepressant, anti-inflammatory, and analgesic properties. This particular derivative is of interest for its potential therapeutic applications.
  • Research and Development: Due to its structural similarities with other bioactive compounds, 4-(2-benzhydryloxyethyl)morpholine; hydrochloride is often used as a lead compound in the synthesis of new medications, making it a key starting point for medicinal chemists.
  • Versatile Applications: Beyond its medicinal use, morpholine derivatives have found importance in the fields of agriculture and material science, contributing to the development of fungicides and advanced polymers.

As you explore 4-(2-benzhydryloxyethyl)morpholine; hydrochloride, consider how such a simple modification to a basic morpholine structure can yield complexity in biological activity and potential therapeutic effects. It serves as a reminder of the creativity involved in chemical synthesis and the ongoing quest for discovering new therapeutic agents.

As renowned chemist Linus Pauling once stated, "The best way to have a good idea is to have a lot of ideas." This sentiment holds true as the exploration of compounds like this one can lead to groundbreaking discoveries in the field of chemistry.

Synonyms
Linadryl hydrochloride
5928-69-8
A 446 hydrochloride
Morpholine, 4-(2-(diphenylmethoxy)ethyl)-, hydrochloride
A 446
beta-Morpholinoethyl benzhydryl ether hydrochloride
DTXSID20207998
Morpholine, 4-[2-(diphenylmethoxy)ethyl]-, hydrochloride
DTXCID70130489
4-(2-benzhydryloxyethyl)morpholine;hydrochloride
2WTP4T4LEG
AKOS040748751
4-[2-(Benzhydryloxy)ethyl]morpholine hydrochloride
Morpholine, 4-[2-(diphenylmethoxy)ethyl]-, hydrochloride (1:1)
4-[2-(Diphenylmethoxy)ethyl]morpholine hydrochloride (1:1); 4-[2-(Benzhydryloxy)ethyl]morpholine hydrochloride; Linadryl hydrochloride