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Roxarsone

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Identification
Molecular formula
C6H6AsNO4Cl
CAS number
121-19-7
IUPAC name
[4-[(2-chloroacetyl)amino]phenyl]arsonic acid
State
State

At room temperature, Roxarsone is in a solid state.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
297.80
Boiling point (Kelvin)
570.95
General information
Molecular weight
263.49g/mol
Molar mass
263.4910g/mol
Density
1.6989g/cm3
Appearence

Roxarsone is a white to light-tan solid powder. It is often odorless and has a crystalline texture.

Comment on solubility

Solubility of [4-[(2-chloroacetyl)amino]phenyl]arsonic Acid

[4-[(2-chloroacetyl)amino]phenyl]arsonic acid, a compound with complex functional groups, exhibits distinctive solubility characteristics that are essential for understanding its behavior in various environments. Its solubility can be influenced by several factors:

  • Polarity: The presence of the arsonic acid functional group contributes to its overall polarity, likely enhancing its solubility in polar solvents like water.
  • Hydrogen Bonding: With its amino and carboxylic acid groups, this compound could engage in hydrogen bonding, further increasing solubility.
  • pH Dependence: The solubility may vary with changes in pH, particularly due to the ionization of the acidic group in varying acidic or basic environments.

In summary, while [4-[(2-chloroacetyl)amino]phenyl]arsonic acid may dissolve well in polar solvents, the extent of its solubility can vary significantly under different conditions. Understanding these solubility dynamics is crucial for applications in pharmaceuticals and environmental chemistry.

Interesting facts

Interesting Facts about 4-[(2-chloroacetyl)amino]phenyl]arsonic acid

4-[(2-chloroacetyl)amino]phenyl]arsonic acid, commonly known in scientific circles, has a rich history in both biochemical research and application. This compound is particularly notable for its role in various fields, ranging from medicinal chemistry to agricultural sciences. Here are some fascinating insights:

  • Historical Significance: This compound, often associated with veterinary medicine, reflects the evolving landscape of drug development over the decades. Its use in the treatment of infections in livestock has been a topic of various studies.
  • Mechanism of Action: 4-[(2-chloroacetyl)amino]phenyl]arsonic acid is believed to function by disrupting biochemical pathways in microbial organisms, showcasing how chemical modifications can enhance efficacy against pathogens.
  • Structural Features: The presence of both chloroacetyl and arsonic functional groups in this compound provides it with unique reactivity. These groups allow for specific interactions that can lead to significant biological effects.
  • Research Applications: Beyond its medicinal use, compounds like this one are often employed in research laboratories to investigate mechanisms of drug resistance and the synthesis of new therapeutic agents.
  • Controversial Aspects: As an organoarsenic compound, it sparks discussions regarding environmental implications and the safety of arsenic-containing compounds in agriculture, highlighting the need for responsible usage.

In conclusion, 4-[(2-chloroacetyl)amino]phenyl]arsonic acid stands as an example of the intricate relationship between chemistry and real-world applications. Its history, mechanisms, and implications in various fields underline its significance in scientific discovery.

Synonyms
5425-62-7
NSC 12629
EINECS 226-569-7
NSC 43640
BRN 2981394
(4-((Chloroacetyl)amino)phenyl)arsonic acid
ARSONIC ACID, (4-((CHLOROACETYL)AMINO)PHENYL)-
Acide monochloroacetamido-4 benzene arsonique [French]
Acide monochloroacetamido-4 benzene arsonique
DTXSID20202605
Arsonic acid, [4-[(chloroacetyl)amino]phenyl]-
DTXCID10125096
3-16-00-01110 (beilstein handbook reference)
4-(2-Chloroacetamido)phenylarsonic acid
ANTINEOPLASTIC-12629
ANTINEOPLASTIC-43640
BWPMHDNLIGQVLN-UHFFFAOYSA-N
NSC12629
NSC43640
NSC-12629
NSC-43640
NS00080930