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Chlorambucil

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Identification
Molecular formula
C14H19Cl2NO2
CAS number
305-03-3
IUPAC name
4-(2-chloroethylamino)benzoic acid
State
State

At room temperature, Chlorambucil is a solid.

Melting point (Celsius)
65.50
Melting point (Kelvin)
338.65
Boiling point (Celsius)
488.70
Boiling point (Kelvin)
761.85
General information
Molecular weight
304.19g/mol
Molar mass
304.1900g/mol
Density
1.2820g/cm3
Appearence

Chlorambucil appears as a white or pale yellow crystalline powder.

Comment on solubility

Solubility of 4-(2-chloroethylamino)benzoic acid

4-(2-chloroethylamino)benzoic acid, known for its interesting chemical properties, demonstrates variable solubility characteristics depending on environmental conditions. Here are some key points regarding its solubility:

  • Polarity: The presence of both a carboxylic acid group and a chloroethyl amino group contributes to distinct polar interactions, making it likely to be soluble in polar solvents.
  • Solvents: This compound typically exhibits better solubility in water and alcohols compared to non-polar solvents.
  • pH Dependence: The solubility is also influenced by pH levels, where the carboxylic acid group can donate a proton, increasing solubility in basic conditions.
  • Temperature Influence: An increase in temperature generally enhances the solubility of solid compounds in liquids, which may apply here.

As a general rule, “like dissolves like,” indicating that the structure of 4-(2-chloroethylamino)benzoic acid allows it to dissolve effectively in polar environments, making it a compound of interest in various chemical applications.

Interesting facts

Exploring 4-(2-chloroethylamino)benzoic acid

4-(2-chloroethylamino)benzoic acid, often referred to as a derivative of benzoic acid, is an intriguing compound due to its distinct structure and biological activities. Here are some interesting facts that highlight its significance:

  • Pharmaceutical Applications: This compound is known for its role in medicinal chemistry, particularly as a potential therapeutic agent. Its structure includes a chloroethylamino group that may contribute to its interaction with biological targets.
  • Research Utility: It serves as a valuable tool in academic and industrial research, aiding in the development of new drugs and understanding metabolic pathways.
  • Analytical Chemistry: The compound’s distinctive functional groups make it a suitable subject for various analytical studies, including spectroscopy and chromatography.
  • Key Precursor: 4-(2-chloroethylamino)benzoic acid can act as a precursor for synthesizing more complex molecules, thereby expanding its applicability in organic synthesis.
  • Potential Biological Activity: Research suggests it may exhibit anticancer properties, making it a compound of interest in the quest for cancer therapy advancements.

In summary, 4-(2-chloroethylamino)benzoic acid is not just a chemical entity but a compound with the potential to impact medicinal chemistry and pharmaceutical research significantly. As scientists continue to explore its properties, we may uncover more of its secrets and enhance our understanding of chemical compounds in biological systems.

Synonyms
2045-23-0
p-((2-Chloroethyl)amino)benzoic acid
BENZOIC ACID, p-(2-CHLOROETHYL)AMINO-
BRN 2803827
DTXSID70174404
DTXCID6096895
SCHEMBL15961877