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Norepinephrine

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Identification
Molecular formula
C8H11NO3
CAS number
51-41-2
IUPAC name
4-[2-(cyclopentylamino)-1-hydroxy-ethyl]benzene-1,2-diol
State
State

At room temperature, norepinephrine is in a solid state. It is typically stored as a dry powder and is converted into a solution form for pharmaceutical use.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
169.18g/mol
Molar mass
169.1770g/mol
Density
1.2800g/cm3
Appearence

Norepinephrine appears as a white to off-white crystalline powder. It is odorless and hygroscopic, meaning it can absorb moisture from the air. When dissolved in water, it forms a clear, colorless solution.

Comment on solubility

Solubility of 4-[2-(cyclopentylamino)-1-hydroxy-ethyl]benzene-1,2-diol

The solubility of 4-[2-(cyclopentylamino)-1-hydroxy-ethyl]benzene-1,2-diol can be of significant interest due to its unique molecular structure. This compound's solubility is influenced by various factors, including:

  • Polar Functional Groups: The presence of hydroxy groups enhances hydrogen bonding with water, suggesting potential for decent solubility in polar solvents.
  • Cyclopentyl Group: The hydrophobic cyclopentyl moiety may limit solubility in water while promoting solubility in organic solvents.
  • Temperature Effects: Increased temperature may enhance solubility due to greater solute-solvent interactions.

In summary, while 4-[2-(cyclopentylamino)-1-hydroxy-ethyl]benzene-1,2-diol exhibits characteristics that may suggest moderate solubility in polar solvents, its cyclopentyl component might favor solubility in non-polar or organic solvents. Laboratory testing is essential to ascertain precise solubility parameters pertinent to various solvents.

Interesting facts

Interesting Facts About 4-[2-(Cyclopentylamino)-1-hydroxy-ethyl]benzene-1,2-diol

This compound represents an intriguing blend of organic chemistry and medicinal applications. As a scientist or a chemistry student, it's fascinating to consider its structural and functional properties in detail.

Key Characteristics:

  • Functional Group Versatility: This compound features hydroxyl groups and an amine, indicating potential for significant reactivity, particularly in biological systems.
  • Potential Applications: Compounds with similar structures are often investigated for their pharmacological properties, including potential as drug candidates for various therapeutic areas.
  • Cyclopentyl Ring: The presence of the cyclopentyl group adds steric hindrance which can be crucial for modifying biological interactions, making this compound particularly interesting for drug design.

Scientific Insights:

One core aspect of studying compounds like this is understanding how small changes in molecular structure can lead to large differences in activity and interaction. As noted by researchers, "A molecule's shape and functional groups dictate its reactivity and compatibility with biological targets."

Moreover, through techniques such as molecular docking and computational chemistry, scientists can predict and optimize the interactions of this compound with its potential targets, paving the way for innovative therapeutic solutions.

In summary, 4-[2-(Cyclopentylamino)-1-hydroxy-ethyl]benzene-1,2-diol is not just a chemical compound; it is a gateway to understanding complex interactions in drug development, making it a thrilling topic of study in contemporary chemistry.

Synonyms
WIN 5591
BRN 3320932
13725-09-2
Protocatechuyl alcohol, alpha-(cyclopentylaminomethyl)-
alpha-((Cyclopentylamino)methyl)-3,4-dihydroxybenzyl alcohol
1,2-Benzenediol, 4-(2-(cyclopentylamino)-1-hydroxyethyl)-
3-13-00-02389 (Beilstein Handbook Reference)
BENZYL ALCOHOL, alpha-((CYCLOPENTYLAMINO)METHYL)-3,4-DIHYDROXY-
4-[2-(cyclopentylamino)-1-hydroxyethyl]benzene-1,2-diol
DTXSID10929753