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Epinephrine

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Identification
Molecular formula
C9H13NO3
CAS number
51-43-4
IUPAC name
4-[2-(ethylamino)-1-hydroxy-ethyl]benzene-1,2-diol
State
State

At room temperature, epinephrine is typically found as a solid in its pure form. In many practical applications, such as in pharmaceuticals, it is used in a liquid solution.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
183.20g/mol
Molar mass
183.2040g/mol
Density
1.2830g/cm3
Appearence

Epinephrine appears as a white to off-white crystalline solid. It is often available as a solution or powder for medical and research purposes. Its crystalline form can sometimes display a faintly pink tinge.

Comment on solubility

Solubility of 4-[2-(ethylamino)-1-hydroxy-ethyl]benzene-1,2-diol

The solubility of 4-[2-(ethylamino)-1-hydroxy-ethyl]benzene-1,2-diol can be influenced by several factors due to its complex structure. Key points to consider include:

  • Polarity: The presence of hydroxyl groups (-OH) enhances the compound's polarity, making it more likely to dissolve in polar solvents such as water.
  • Hydrogen bonding: This compound can form hydrogen bonds with water molecules, which typically contributes to increased solubility in aqueous environments.
  • Alkyl chain influence: The ethylamino group adds hydrophobic characteristics, which can potentially affect overall solubility depending on the solvent used.

In general, while compounds with polar functional groups tend to be soluble in polar solvents, the presence of the ethylamino group may lead to a more complex solubility behavior. As a result, we can expect:

  • Good solubility in polar solvents, especially water.
  • Limited solubility in non-polar solvents, due to hydrophobic interactions.

Understanding these solubility characteristics is crucial, as they can significantly affect the compound's behavior in various chemical environments and applications.

Interesting facts

Interesting Facts About 4-[2-(ethylamino)-1-hydroxy-ethyl]benzene-1,2-diol

This intriguing compound is known for its multifaceted applications and unique structure. As a derivative of catechol, it showcases the capability of phenolic compounds to undergo various chemical transformations that enhance their functional properties.

Key Features:

  • Biological Activity: The presence of an ethylamino group suggests potential bioactivity, which can lead to interesting medicinal applications. Various studies focus on compounds with amino functionalities that exhibit antimicrobial and antitumor activities.
  • Structural Complexity: With multiple hydroxyl groups, this compound demonstrates significant solvent interactions, which can influence its reactivity and compatibility with other substances.
  • Research Interest: The chemical's unique arrangement has attracted attention in drug design and development, prompting investigations into its potential as a template for new therapeutic agents.

As a point of interest, researchers have noted that such compounds can serve as valuable scaffolds in the synthesis of more complex molecules. The intricate balance between hydrophilic and hydrophobic parts of the molecule often determines the biological activity and interaction dynamics in cellular environments.
Particularly in the fields of medicinal chemistry, understanding how modifications in structure can affect activity plays a crucial role in the design of effective drugs. As one researcher famously stated, "Every atom counts," emphasizing the importance of small changes in molecular architecture.

Overall, 4-[2-(ethylamino)-1-hydroxy-ethyl]benzene-1,2-diol exemplifies the fascinating world of organic chemistry, wherein slight variations can lead to significant changes in properties and applications.

Synonyms
Ethyladrenaline
N-Ethylnoradrenaline
Aethyladrenalin
Aethyladrenalin [German]
R 007XL
2947-00-4
Protocatechuyl alcohol, alpha-((ethylamino)methyl)-
4-(2-(Ethylamino)-1-hydroxyethyl)-1,2-benzenediol
1,2-Benzenediol, 4-(2-(ethylamino)-1-hydroxyethyl)-
3,4-Dihydroxy-alpha-((ethylamino)methyl)benzyl alcohol
BENZYL ALCOHOL, 3,4-DIHYDROXY-alpha-((ETHYLAMINO)METHYL)-
4-[2-(Ethylamino)-1-hydroxyethyl]-1,2-benzenediol
4-[2-(ethylamino)-1-hydroxyethyl]benzene-1,2-diol
Methyladrenalin
SCHEMBL9768173
DTXSID80951980