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Dopamine

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Identification
Molecular formula
C8H11NO2
CAS number
51-61-6
IUPAC name
4-[2-(ethylamino)-1-hydroxy-ethyl]phenol
State
State

At room temperature, dopamine is typically found as a solid in the form of a crystalline powder. It is often stored as a hydrochloride salt to enhance its stability and solubility for practical uses.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
214.00
Boiling point (Kelvin)
487.15
General information
Molecular weight
153.18g/mol
Molar mass
153.1810g/mol
Density
1.2640g/cm3
Appearence

Dopamine, in its pure form, is a white to off-white crystalline powder. It is hygroscopic and has a bitter taste. Dopamine can appear differently when in solution, generally forming clear to slightly yellow solutions depending on concentration and purity.

Comment on solubility

Solubility of 4-[2-(ethylamino)-1-hydroxy-ethyl]phenol

The solubility of 4-[2-(ethylamino)-1-hydroxy-ethyl]phenol can be influenced by several factors, including its molecular structure and the presence of functional groups. This compound has both hydrophilic and hydrophobic characteristics due to the presence of the hydroxyl (-OH) group and the ethylamino (-NH2) side chain. As a result, its solubility profile can be described as follows:

  • Water Solubility: Due to the presence of the hydroxyl group, 4-[2-(ethylamino)-1-hydroxy-ethyl]phenol is expected to exhibit moderate solubility in water. The polar nature of the -OH group facilitates interactions with water molecules.
  • Organic Solvents: The compound may also show solubility in organic solvents like ethanol or methanol, where its hydrophobic phenolic structure can interact favorably with non-polar segments of the solvent, enhancing its overall solubility.
  • Temperature Effects: As with many organic compounds, solubility may increase with temperature. It is often observed that raising the temperature of a solution can increase the solubility of solids in liquids.
  • pH Influence: The solubility of 4-[2-(ethylamino)-1-hydroxy-ethyl]phenol can vary significantly with pH. In acidic environments, protonation of the amino group may enhance solubility, while in basic conditions, the compound could experience increased ionization.

In conclusion, while the solubility of 4-[2-(ethylamino)-1-hydroxy-ethyl]phenol is influenced by its structure and surrounding conditions, it is reasonable to anticipate that it displays moderate solubility in water and various organic solvents.

Interesting facts

Interesting Facts about 4-[2-(ethylamino)-1-hydroxy-ethyl]phenol

4-[2-(ethylamino)-1-hydroxy-ethyl]phenol, commonly known in research contexts, showcases a unique structure that combines both aromatic and aliphatic features, making it notable in the realm of organic chemistry. Here are some fascinating points about this compound:

  • Diverse Applications: This compound has applications in pharmaceuticals, particularly in the development of drugs that target specific receptors in the body, which can lead to enhanced therapeutic efficacy.
  • Biochemical Relevance: Its structure includes a phenolic group, which is significant in biochemical functions, possibly acting as a signaling molecule or an antioxidant.
  • Structure-Activity Relationship: The presence of an ethylamino group in the molecule may influence its biological activity, affecting how it interacts with biological targets, thus making it a subject for ongoing research.
  • Research Interest: Scientists are particularly interested in compounds like this one that carry both a hydroxy group and an amino group, as they can participate in hydrogen bonding, influencing their reactivity and solubility.
  • Synthesis Pathways: The synthesis of this compound often involves multi-step reactions, highlighting the complexity and creativity required in synthetic organic chemistry.

The exploration of 4-[2-(ethylamino)-1-hydroxy-ethyl]phenol continues to provide insights into the modifications of chemical structures that can lead to variations in biological activity, which is vital for students and researchers alike. As emphasized by many chemists, "Understanding the details of molecular structure can illuminate pathways for innovation." This compound exemplifies the intersection of structure and function that is crucial in the field of chemistry.

Synonyms
Ethylnorsynephrine
BRN 3258858
4232-09-1
alpha-(Ethylaminomethyl)-p-hydroxybenzyl alcohol
alpha-((Ethylamino)methyl)-4-hydroxybenzenemethanol
Benzenemethanol, alpha-((ethylamino)methyl)-4-hydroxy-
BENZYL ALCOHOL, alpha-((ETHYLAMINO)METHYL)-p-HYDROXY-
3-13-00-02241 (Beilstein Handbook Reference)
Benzenemethanol, alpha-((ethylamino)methyl)-4-hydroxy-(9CI)
4-[2-(ethylamino)-1-hydroxyethyl]phenol
SCHEMBL6457448
DTXSID10962423