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Roxarsone

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Identification
Molecular formula
C6H6AsNO4
CAS number
121-19-7
IUPAC name
[4-[(2-hydroxyacetyl)amino]phenyl]arsonic acid
State
State

Roxarsone is a solid powder at room temperature.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
263.04g/mol
Molar mass
263.0720g/mol
Density
1.5600g/cm3
Appearence
  • White crystalline powder
Comment on solubility

Solubility of [4-[(2-hydroxyacetyl)amino]phenyl]arsonic acid

[4-[(2-hydroxyacetyl)amino]phenyl]arsonic acid, with its complex structure, exhibits notable solubility characteristics. This compound can be analyzed based on several solubility factors:

  • Polarity: The presence of hydroxyl (-OH) and amino (-NH2) functional groups enhances the polarity of the molecule, allowing for better interaction with polar solvents such as water.
  • pH Dependence: The solubility can also vary with pH due to the presence of acidic arsonic acid groups, which can ionize at higher pH levels, improving solubility in aqueous solutions.
  • Temperature Influence: Generally, like many organic compounds, solubility increases with temperature, making higher temperatures favorable for dissolving this compound in solvents.
  • Alcohol Solubility: In addition to water, compounds of this nature often show solubility in alcohols, such as ethanol, which can be beneficial for specific applications or formulations.

As a result, it can be said that [4-[(2-hydroxyacetyl)amino]phenyl]arsonic acid is relatively soluble in polar solvents, particularly in an aqueous environment, influenced by pH and temperature. This solubility profile can play a vital role in its application and handling in various chemical processes.

Interesting facts

Interesting Facts about 4-[(2-hydroxyacetyl)amino]phenyl]arsonic acid

4-[(2-hydroxyacetyl)amino]phenyl]arsonic acid, often abbreviated as HAPA, is a unique organoarsenic compound with a variety of intriguing properties and applications. Here are some noteworthy aspects of this fascinating compound:

  • Historical Usage: This compound has been studied for its potential use as a therapeutic agent, particularly in the treatment of parasitic infections and certain types of cancer due to its ability to interact with biological systems.
  • Biological Significance: Organosilicon compounds, such as HAPA, often exhibit interesting biological activities. HAPA’s structure allows it to interact with specific enzymes, making it a target for research into novel pharmaceutical applications.
  • Toxicity Research: Scientists are actively investigating the toxicity and environmental impact of arsenic-containing compounds. Understanding HAPA can provide insights into the potential risks and safe handling procedures associated with organoarsenic species.
  • Analytical Chemistry: HAPA has been utilized in analytical chemistry as a standard substance in the calibration of instruments and methods designed to detect other arsenic compounds in various matrices.
  • Innovative Applications: Ongoing research is exploring the use of HAPA in developing new materials and techniques across fields such as biochemistry, environmental science, and pharmaceuticals.

In summary, 4-[(2-hydroxyacetyl)amino]phenyl]arsonic acid exemplifies the complexity and versatility of organoarsenic compounds. Its varied applications highlight the intersection of chemistry, biology, and environmental science, making it a compound worth further exploration. As the research continues to evolve, we may uncover even more applications and implications of HAPA that can benefit both science and society.

Synonyms
Glycarsamide
144-87-6
4-(Glycolloylamino)phenylarsonic acid
Astryl
N-Glycolylarsanilic acid
[4-[(2-hydroxyacetyl)amino]phenyl]arsonic acid
N-Glycoloylarsanilic acid
3ACA67L6DG
Arsanilic acid, N-glycoloyl-
p-Glycolylaminophenylarsinic acid
NSC-221701
NSC163966
[4-[(HYDROXYACETYL)AMINO]PHENYL]ARSONIC ACID
NSC-163966
(4-((HYDROXYACETYL)AMINO)PHENYL)ARSONIC ACID
UNII-3ACA67L6DG
EINECS 205-643-2
GLYCARSAMIDE [MI]
NCIStruc1_001581
NCIStruc2_001935
SCHEMBL225259
CHEMBL1741842
DTXSID40162595
p-Glycoloylaminophenylarsinic acid
p-Glycoloylaminophenylarsonic acid
p-Glycolylaminobenzenearsonic acid
p-Glycoloylaminobenzenearsonic acid
QABXFDAPQQVMKL-UHFFFAOYSA-N
p-Hydroxyacetamidophenylarsonic acid
4-(glycoloylamino)phenylarsonic acid
CCG-36631
MFCD00068960
NCGC00014459
NCI163966
NSC221701
AKOS023506036
NSC 221701
NCGC00014459-02
NCGC00097564-01
NCI60_001246
Arsonic acid, [4-[(hydroxyacetyl)amino]phenyl]-
Q27256967