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Guaiacol

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Identification
Molecular formula
C8H10O2
CAS number
90-05-1
IUPAC name
4-(2-hydroxyethyl)-2-methoxy-phenol
State
State

Guaiacol is typically a liquid at room temperature.

Melting point (Celsius)
28.00
Melting point (Kelvin)
301.15
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
138.16g/mol
Molar mass
138.1640g/mol
Density
1.1290g/cm3
Appearence

Guaiacol is a colorless to pale yellow aromatic oil. It sometimes appears slightly greenish in thicker layers or when impurities are present.

Comment on solubility

Solubility of 4-(2-hydroxyethyl)-2-methoxy-phenol

The solubility characteristics of 4-(2-hydroxyethyl)-2-methoxy-phenol, also known as MEHHP, can be quite fascinating due to its unique molecular structure. This compound, which contains both a hydroxyl group and a methoxy group, often exhibits enhanced solubility in various solvents. Here's a deeper look into its solubility properties:

  • Polar Solvents: 4-(2-hydroxyethyl)-2-methoxy-phenol shows good solubility in polar solvents, especially in water, due to the presence of the hydroxyl (-OH) group which can form hydrogen bonds with water molecules.
  • Non-Polar Solvents: The methoxy group (-OCH3) adds a degree of non-polarity, meaning that while it is soluble in polar solvents, its solubility in non-polar solvents may be limited.
  • Concentration Effects: The solubility can also depend on the concentration, temperature, and presence of other solutes in the solution, which can influence the ability of the compound to dissolve.

In summary, while 4-(2-hydroxyethyl)-2-methoxy-phenol typically demonstrates good solubility in polar environments, its solubility behavior in non-polar media is not as pronounced. This dual characteristic is crucial for applications in various chemical and pharmaceutical processes where the solubility of compounds significantly affects their utility.

Interesting facts

Interesting Facts About 4-(2-Hydroxyethyl)-2-methoxy-phenol

4-(2-Hydroxyethyl)-2-methoxy-phenol, often referred to by its more familiar names, is a fascinating compound with a variety of applications in modern science and industry. Here are some intriguing insights into this versatile molecule:

  • Use in Biology: This compound is notable for its role as an antioxidant. Oxidative stress can lead to cellular damage, and compounds like this one help protect cells by scavenging free radicals.
  • Pharmaceutical Applications: The hydroxy and methoxy groups in its structure allow it to interact with biological systems effectively. This makes it a potential candidate for drug formulation, providing therapeutic benefits for various conditions.
  • Cosmetic Industry: With its antioxidant properties, 4-(2-hydroxyethyl)-2-methoxy-phenol is used in skincare formulations. It helps in preventing skin aging and enhances the stability of cosmetic products.
  • Environmental Impact: As an environmentally friendly alternative, compounds like this one are explored for their ability to replace harmful substances in industrial applications, promoting sustainability.

Chemical Properties and Reactions

This compound can participate in several chemical reactions, thanks to its functional groups. It can undergo:

  • Substitution reactions: The presence of the hydroxy and methoxy groups makes it susceptible to further modification.
  • Redox reactions: As an antioxidant, it is actively involved in reducing oxidative species.
  • Hydrophilic interactions: The hydroxyethyl group enhances its solubility in biological media, allowing better absorption in various applications.

In conclusion, 4-(2-hydroxyethyl)-2-methoxy-phenol is much more than just a chemical formula—it is a compound with significant implications in health and industry. As research continues to unfold, its potential uses are likely to expand, proving that even the smallest molecules can have profound impacts.

Synonyms
Homovanillyl alcohol
2380-78-1
4-(2-Hydroxyethyl)-2-methoxyphenol
3-METHOXY-4-HYDROXYPHENYLETHANOL
Benzeneethanol, 4-hydroxy-3-methoxy-
MOPET
4-(2-Hydroxyethyl)guaiacol
9A7EE8MS6A
EINECS 219-175-1
XHUBSJRBOQIZNI-UHFFFAOYSA-
DTXSID40178494
Hydroxymethoxyphenethyl Alcohol
Alcohol, Hydroxymethoxyphenethyl
3 Methoxy 4 hydroxyphenylethanol
DTXCID70100985
inchi=1/c9h12o3/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,10-11h,4-5h2,1h3
4-Hydroxy-3-methoxyphenethanol
Vanillylmethanol
Guaiacyl ethanol
4-Hydroxy-3-methoxyphenethyl alcohol
4-Hydroxy-3-methoxyphenylethyl alcohol
(4-Hydroxy-3-methoxyphenyl)ethanol
2-(4-Guaiacyl)-ethanol
2-(4-Hydroxy-3-methoxyphenyl)-ethanol
UNII-9A7EE8MS6A
Homovanillin alcohol
Homovanilline alcohol
MFCD00002903
Homovanillyl alcohol, 99%
SCHEMBL43681
CHEMBL3747068
4-Hydroxy-3-methoxybenzeneethanol
CHEBI:173769
4-Hydroxy-3-methoxy-Benzeneethanol
BCP30361
HY-N7513
AKOS003382015
CCG-356420
FH66260
FS-3438
4-(2-Hydroxyethyl)-2-methoxyphenol #
DB-046251
CS-0131118
NS00027490
D95086
EN300-1250800
Q5891855
4-Hydroxy-3-methoxyphenethanol pound>>4-(2-Hydroxyethyl)-2-methoxyphenol
VTL