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Dopamine

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Identification
Molecular formula
C8H11NO2
CAS number
51-61-6
IUPAC name
4-[2-(methylamino)ethyl]benzene-1,2-diol
State
State

At room temperature, dopamine is typically in a solid state in its powdered form but in its pharmaceutical applications, it is often found dissolved in an aqueous solution for injection.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
309.15
Boiling point (Kelvin)
582.30
General information
Molecular weight
153.18g/mol
Molar mass
153.1790g/mol
Density
1.2600g/cm3
Appearence

Dopamine in its pure form appears as a white to off-white crystalline powder. It is generally used in its hydrochloride salt form which is more stable and water-soluble. It should be stored under inert gas and in a dark environment to prevent oxidation, which can cause discoloration.

Comment on solubility

Solubility of 4-[2-(methylamino)ethyl]benzene-1,2-diol (C8H11NO2)

The solubility of 4-[2-(methylamino)ethyl]benzene-1,2-diol is an intriguing aspect worth exploring.
Due to its molecular structure, this compound exhibits a degree of solubility in various solvents:

  • Polar solvents: The presence of the hydroxyl (-OH) groups suggests that this compound is expected to dissolve well in polar solvents such as water and alcohols. This is due to hydrogen bonding capabilities.
  • Non-polar solvents: Conversely, its solubility in non-polar solvents is likely to be limited. The aromatic ring may repel interactions with non-polar molecules.

In general, compounds with functional groups like -NH2 and -OH tend to display increased solubility in polar environments:

  • Hydrogen bonding: The ability to form hydrogen bonds significantly enhances solubility in water.
  • Molecular interactions: Other organic solvents with polar characteristics can also solvate the compound effectively.

In practical applications, understanding the solubility of 4-[2-(methylamino)ethyl]benzene-1,2-diol can be crucial for its use in pharmaceuticals and organic synthesis. The solubility will dictate the appropriate conditions for reactions, formulations, and stability in diverse environments.

Interesting facts

Interesting Facts about 4-[2-(methylamino)ethyl]benzene-1,2-diol

4-[2-(methylamino)ethyl]benzene-1,2-diol is a fascinating compound that has garnered interest in various scientific fields, particularly in medicinal chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Structural Versatility: The compound features a benzene ring connected to a diol group (two hydroxyl groups) and an ethyl chain with a methylamino substituent. This unique structure contributes to its various interactions with biological systems, making it a candidate for drug development.
  • Potential Applications: Due to its unique functional groups, it might possess properties that can be exploited in the treatment of certain conditions. Researching compounds like this can lead to breakthroughs in pharmaceuticals targeting specific receptors in the body.
  • Biological Activity: Compounds with amino groups, like this one, often demonstrate interesting biological activities. They can act as modulators of neurotransmitter systems or have antioxidant properties due to the presence of hydroxyl groups.
  • Research Opportunities: The ability to modify the methylamino group opens up pathways for synthesizing analogs of this compound, which may display enhanced efficacy or reduced side effects in therapeutic settings.
  • Synthetic Pathways: The synthesis of this compound can be an exciting challenge for chemists. Routes may involve selective functionalization of the benzene moiety, allowing for the refinement of its pharmacological characteristics.

Overall, the exploration of 4-[2-(methylamino)ethyl]benzene-1,2-diol holds significant promise for future studies, showcasing the potential for innovations in drug design and providing new insights into chemical behavior and biological interactions.

Synonyms
epinine
deoxyepinephrine
501-15-5
N-Methyldopamine
Desoxyepinephrine
4-[2-(methylamino)ethyl]benzene-1,2-diol
Deoxyadrenaline
Epyamine
Epinin
Deoxyephinephrine
4-(2-Methylaminoethyl)pyrocatechol
UNII-R7339QLN1C
1,2-Benzenediol, 4-(2-(methylamino)ethyl)-
R7339QLN1C
N-2-(3,4-dihydroxyphenyl)ethylmethylamine
4-(2-Methylamino-ethyl)-benzene-1,2-diol
EINECS 207-919-8
3,4-dihydroxy-N-methylphenethylamine
N-methyl-3,4-dihydroxyphenethylamine
1-(3,4-dihydroxyphenyl)-2-methylaminoethane
CHEBI:10554
1,2-Benzenediol, 4-[2-(methylamino)ethyl]-
4-(beta-Methylaminoethyl)catechol
DTXSID10198205
4-[2-(Methylamino)ethyl]-1,2-benzenediol
PYROCATECHOL, 4-(2-(METHYLAMINO)ETHYL)-
EPININE (USP IMPURITY)
EPININE [USP IMPURITY]
Desoxyadrenaline
4-(2-(Methylamino)ethyl)-1,2-Benzenediol
DEOXIEPINEPHRINE
Lopac-D-5886
Biomol-NT_000002
Lopac0_000390
SCHEMBL67772
DEOXYEPINEPHRINE [MI]
CHEMBL31088
ADRENALINE IMPURITY 34
BPBio1_001125
BDBM81489
DEOXYEPINEPHRINE [WHO-DD]
DTXCID00120696
NSC_4382
PDSP1_001130
PDSP2_001114
AKOS006242434
CCG-204484
DB13917
SDCCGSBI-0050377.P002
CAS_62-32-8
NCGC00015355-01
NCGC00015355-02
NCGC00015355-03
NCGC00015355-04
NCGC00162139-01
NCGC00162139-02
DB-049929
N-Methyl-2-(3,4-dihydroxyphenyl)ethylamine
NS00032005
4-[2-(Methylamino)ethyl]-1,2-benzenediol #
C07453
G87442
benzene, 1,2-dihydroxy-4-(2-methylamino)ethyl-
EN300-1869983
Q5260066
BRD-K33151569-003-09-7
207-919-8