4-(2-Aminoethyl)phenol | Solubility of Things

Identification

Molecular formula

C₈H₁₁NO

CAS number

7149-10-2

IUPAC name

4-[2-(methylamino)ethyl]phenol

State

At room temperature, 4-(2-Aminoethyl)phenol is typically found in a solid state, usually in the form of a crystalline powder.

Melting point (Celsius)

58.00

Melting point (Kelvin)

331.15

Boiling point (Celsius)

263.00

Boiling point (Kelvin)

536.15

General information

Molecular weight

151.18g/mol

Molar mass

151.2140g/mol

Density

1.1290g/cm³

Appearence

4-(2-Aminoethyl)phenol appears as a white or off-white crystalline solid. It may also be found as a powder. The compound is generally stable under recommended storage conditions and is hygroscopic, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of 4-[2-(methylamino)ethyl]phenol

The solubility of 4-[2-(methylamino)ethyl]phenol is influenced by several factors due to its unique molecular structure. Primarily, this compound possesses both hydrophilic and hydrophobic characteristics that can affect how well it interacts with various solvents.

Factors Affecting Solubility

Molecular Structure: The presence of the hydroxyl group (-OH) allows for potential hydrogen bonding with water, enhancing its solubility in polar solvents.
Amine Group: The methylamino group introduces additional sites for interaction, which can improve solubility in both polar and some non-polar environments.
Temperature: Like many organic compounds, increasing the temperature generally improves solubility, as kinetic energy allows for greater interactions with solvent molecules.

Moreover, the solubility behavior can vary significantly between different solvents. For instance:

In water, the compound may exhibit moderate solubility due to its ability to form hydrogen bonds.
In organic solvents, solubility might be less predictable and can depend on the solvent's polarity.

To summarize, the solubility of 4-[2-(methylamino)ethyl]phenol is an intriguing topic that brings into play the balance between hydrophilic and hydrophobic interactions, temperature effects, and solvent choice. As one delves deeper into the compound's characteristics, understanding these solubility aspects can open pathways for its potential applications in various fields.

Interesting facts

Exploring 4-[2-(methylamino)ethyl]phenol

4-[2-(methylamino)ethyl]phenol, also known as a derivative of phenol, encapsulates significant interest within the realms of both organic and medicinal chemistry. This compound demonstrates remarkable versatility which can be attributed to its unique structural features.

Key Features and Applications

Pharmaceutical Relevance: This compound is often studied for its potential therapeutic applications, particularly in the field of neuropharmacology. It holds promise in the development of drugs aimed at treating various psychological disorders due to its interaction with neurotransmitter systems.
Synergistic Effects: The presence of the methylamino group significantly enhances the compound's reactivity. This structural modification can improve bioavailability and efficacy, making it an exciting candidate for further research.
Research Potential: The compound serves as a valuable building block in the synthesis of more complex structures, enabling chemists to explore novel compounds that may exhibit unique properties and functions not seen in simpler molecules.

Scientific Insights

Interestingly, the presence of the hydroxyl group provides strong hydrogen-bonding capabilities, influencing the compound's interaction with biological systems. Researchers often emphasize the importance of such interactions in the development of targeted therapies.

Quote from a leading chemist: "Understanding the subtle changes in molecular structure can unlock new pathways in drug discovery. Compounds like 4-[2-(methylamino)ethyl]phenol exemplify how modifications can lead to profound biological effects."

Overall, 4-[2-(methylamino)ethyl]phenol presents an intriguing study subject that bridges the gap between basic chemical research and applied pharmaceutical sciences, encouraging ongoing exploration and innovation in chemical synthesis.

Synonyms

N-Methyltyramine

370-98-9

4-[2-(Methylamino)ethyl]phenol

N-Methyl-p-tyramine

Methyl-4-tyramine

4-(2-(Methylamino)ethyl)phenol

4-Hydroxy-N-methylphenethylamine

4-(2-METHYLAMINO-ETHYL)-PHENOL

Tyramine, N-methyl-

p-(2-Methylaminoethyl)phenol

N-Methyl-4-tyramine

Phenol, 4-[2-(methylamino)ethyl]-

p-(2-(Methylamino)ethyl)phenol

WIN 5582

methyl tyramine

p-[2-(Methylamino)ethyl]phenol

UNII-G3S4E2F7TA

EINECS 206-731-3

Phenol, 4-(2-(methylamino)ethyl)-

4-(2-Methylaminoethyl)phenol

NSC 113958

BRN 2357129

Phenol, p-[2-(methylamino)ethyl]-

NSC-113958

G3S4E2F7TA

PHENOL, p-(2-METHYLAMINOETHYL)-

CHEMBL5169925

CHEBI:17458

DTXSID60190496

p-[2-(methylamino)ethyl]-Phenol

4-(2-(methylamino)ethyl)-Phenol

4-[2-(methylamino)ethyl]-Phenol

{p-[2-(Methylamino)ethyl]phenol}

4-13-00-01790 (Beilstein Handbook Reference)

PHENOL, P-(2-(METHYLAMINO)ETHYL)-

N-METHYL-N-(2-(4-HYDROXYPHENYL)ETHYL)AMINE

p-(2-(Methylamino)ethyl)-phenol

(p-(2-(methylamino)ethyl)phenol)

benzene, 1-hydroxy-4-(2-methylamino)ethyl-

N-methyl-N-(2-[4-hydroxyphenyl]ethyl)amine

4-Hydroxy-N-methylphenethylamine; Methyl-4-tyramine; p-(2-(Methylamino)ethyl)phenol

Tyramine, Nmethyl

MFCD00870493

p(2Methylaminoethyl)phenol

4HydroxyNmethylphenethylamine

p(2(Methylamino)ethyl)phenol

Phenol, p(2methylaminoethyl)

SCHEMBL274906

Phenol, 4(2(methylamino)ethyl)

DTXCID70112987

BDBM50601684

NSC113958

AKOS006273439

FS-4906

HY-W153897

NCGC00488573-01

Phenol, 4(2(methylamino)ethyl) (9CI)

CS-0210311

NS00030156

N-methyl-N-(2-[4-hydroxyphenyl]ethyl) amine

C02442

EN300-233508

G78327

AA-504/21027007

Q309527

BRD-K79134921-001-01-2