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Diclofop-methyl

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Identification
Molecular formula
C16H14Cl2O4
CAS number
51338-27-3
IUPAC name
[4-[(2,2-dichloroacetyl)-methyl-amino]phenyl] furan-2-carboxylate
State
State

At room temperature, diclofop-methyl is typically found in a solid state as a powder. This stable form allows it to be easily handled in chemical processes and applications.

Melting point (Celsius)
38.00
Melting point (Kelvin)
311.15
Boiling point (Celsius)
432.00
Boiling point (Kelvin)
705.15
General information
Molecular weight
372.19g/mol
Molar mass
372.1680g/mol
Density
1.4290g/cm3
Appearence

Diclofop-methyl appears as an off-white to pale yellow powder. It may exhibit slight variances in color depending on the specific batch and conditions of storage. The powder has no distinctive odor and maintains its powdered, crystalline form under standard conditions.

Comment on solubility

Solubility Characteristics

The solubility of 4-[(2,2-dichloroacetyl)-methyl-amino]phenyl furan-2-carboxylate can vary significantly depending on several factors such as solvent choice, temperature, and pH. This compound showcases unique features influencing its solubility.

Factors Affecting Solubility

  • Polarity of Solvent: The solubility can be generally expected to be higher in polar solvents due to the presence of functional groups capable of hydrogen bonding.
  • Temperature: Increased temperature typically enhances solubility as it promotes molecular motion, allowing for better interactions with solvent molecules.
  • pH Levels: The solubility may also be susceptible to changes in pH, which can affect the ionization of the carboxylate group.

In summary, while 4-[(2,2-dichloroacetyl)-methyl-amino]phenyl furan-2-carboxylate is expected to exhibit moderate solubility in aqueous solutions, it's advisable to carry out specific solubility tests under controlled conditions for accurate and comprehensive understanding.

Interesting facts

Interesting Facts about 4-[(2,2-Dichloroacetyl)-methyl-amino]phenyl furan-2-carboxylate

This compound, known for its intricate structure and diverse applications, is a fascinating subject for both chemists and students alike. Here are some compelling points to consider:

  • Functional Versatility: The presence of multiple functional groups such as the furan ring and carboxylate moiety makes this compound a versatile building block in organic synthesis and medicinal chemistry.
  • Pharmacological Potential: Compounds similar to this one may exhibit interesting biological activities, including but not limited to antimicrobial and anticancer properties. This opens avenues for research into new pharmaceuticals.
  • Chlorine Atoms: The incorporation of chlorine atoms, particularly the dichloroacetyl group, can enhance lipophilicity, improving the compound's ability to penetrate cellular membranes, which is crucial for drug design.
  • Environmental Considerations: With increasing attention on environmentally-friendly processes, the synthesis and application of chlorinated compounds require careful consideration regarding their environmental impact, prompting the need for innovative and sustainable practices.
  • Chemical Reactivity: The carboxylate group can engage in various reactions, which can be employed in the functionalization of other molecules, making this compound a valuable key intermediate in organic reactions.

In the words of a seasoned chemist, “Understanding the intricate dance of electrons and functional groups opens up a universe of possibilities in chemical research.” This compound embodies that sentiment, showcasing the beauty and complexity of chemical science.

As research progresses, uncovering the full spectrum of its utility and effects could lead to significant advancements in both industrial applications and health sciences.

Synonyms
DILOXANIDE FUROATE
3736-81-0
Dichlofurazol
Furentomin
Histomibal
4-(2,2-Dichloro-N-methylacetamido)phenyl furan-2-carboxylate
[4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate
MLS000028653
Amebiazol
Diloxanide furoate [USP]
NSC-759146
2-Furoic acid, ester with 2,2-dichloro-4'-hydroxy-N-methylacetanilide
Diloxanid furoate
SMR000058857
CHEBI:4601
YP4N72IW34
Diclofurazol
DTXSID8048999
Entamide furoate
2-Furancarboxylic acid, 4-[(dichloroacetyl)methylamino]phenyl ester
NCGC00016637-07
Miforon
CAS-3736-81-0
2-Furancarboxylic acid, 4-((dichloroacetyl)methylamino)phenyl ester
Diloxanide furoate (USP)
2,2-dichloroacetamido-4-n-methylphenyl 2-furoate
Entamide 2-furoate
4-(n-methyl-2,2-dichloroacetamido)phenyl 2-furoate
Furamide (amebicide)
DTXCID8028925
2,2-Dichloro-N-(4-hydroxyphenyl)-N-methylacetamide 2-furoic acid ester
2,2-DICHLORO-N-[4-HYDROXYPHENYL]-N-METHYLACETAMIDE 2-FUROIC ACID ESTER
SR-01000003134
EINECS 223-108-1
MFCD00083302
8073 CB
UNII-YP4N72IW34
Diloxanidi furoas
CB 8073
Diloxanide furoate (TN)
Opera_ID_1633
Prestwick0_000903
Prestwick1_000903
Prestwick2_000903
Prestwick3_000903
4-((Dichloroacetyl)methylamino)phenyl 2-furoate
SCHEMBL23381
BSPBio_000746
2,2-Dichloroacetamideo-4-N-methylphenyl 2-furoate
4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furoat
cid_19529
MLS001148648
Diloxanide furoate (Standard)
SPBio_002945
4-(N-Methyl-2,2-dichloroacetamideo)phenyl 2-furoate
BPBio1_000822
DILOXANIDE FUROATE [MI]
CHEMBL1334860
BDBM70295
HY-B1147R
4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furancarboxylat
BDYYDXJSHYEDGB-UHFFFAOYSA-N
4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furoat [IUPAC]
HMS1570F08
HMS2093N21
HMS2097F08
HMS2234P06
HMS3371I07
HMS3714F08
Pharmakon1600-01505532
DILOXANIDE FUROATE [MART.]
DILOXANIDE FUROATE [USP-RS]
DILOXANIDE FUROATE [WHO-DD]
DILOXANIDE FUROATE [WHO-IP]
HY-B1147
Tox21_113492
4-(2,2-Dichlor-N-methylacetamido)phenyl 2-furancarboxylat [IUPAC]
EX-A10695
NSC759146
AKOS016014036
Tox21_113492_1
CCG-213477
CS-4751
DB14638
FD63298
NSC 759146
DILOXANIDI FUROAS [WHO-IP LATIN]
NCGC00016637-01
NCGC00016637-02
NCGC00016637-03
NCGC00016637-04
NCGC00016637-05
NCGC00016637-06
NCGC00016637-10
NCGC00023178-03
NCGC00023178-04
NCGC00023178-05
DILOXANIDE FUROATE [USP MONOGRAPH]
MS-24905
SBI-0206798.P001
DB-228787
AB00383052
NS00030183
C07637
D02480
F85244
AB00383052_13
Diloxanide furoate 100 microg/mL in Acetonitrile
EN300-18538237
Q799564
SR-01000003134-2
SR-01000003134-4
BRD-K10974103-001-03-9
BRD-K10974103-001-14-6
BRD-K10974103-001-21-1
[4-[(2,2-dichloroacetyl)-methyl-amino]phenyl] furan-2-carboxylate
[4-[2,2-bis(chloranyl)ethanoyl-methyl-amino]phenyl] furan-2-carboxylate
2-Furancarboxylic acid, 4-[(2,2-dichloroacetyl)methylamino]phenyl ester
Diloxanide furoate, United States Pharmacopeia (USP) Reference Standard
2-furancarboxylic acid [4-[(2,2-dichloro-1-oxoethyl)-methylamino]phenyl] ester
furan-2-carboxylic acid [4-[(2,2-dichloroacetyl)-methyl-amino]phenyl] ester