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Methylene blue

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Identification
Molecular formula
C16H18N3SCl
CAS number
61-73-4
IUPAC name
4-[[3-[2-(diethylamino)ethyl]-1H-benzimidazol-3-ium-2-yl]sulfanyl]-N,N-diethyl-aniline
State
State

At room temperature, methylene blue is typically found as a solid in the form of its salt, methylene blue chloride. When dissolved, it forms a blue liquid commonly used in laboratories and medicine.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
319.85g/mol
Molar mass
319.8510g/mol
Density
1.0480g/cm3
Appearence

Methylene blue appears as a dark green crystalline powder in its solid form. When dissolved in water, it forms a deep blue solution, which can be used as a dye or stain. This vibrant color is characteristic of methylene blue solutions.

Comment on solubility

Solubility of 4-[[3-[2-(diethylamino)ethyl]-1H-benzimidazol-3-ium-2-yl]sulfanyl]-N,N-diethyl-aniline

The solubility of the compound 4-[[3-[2-(diethylamino)ethyl]-1H-benzimidazol-3-ium-2-yl]sulfanyl]-N,N-diethyl-aniline can be influenced by a variety of factors:

  • Polarity: The presence of both hydrophobic (diethyl groups) and hydrophilic (benzimidazolium and sulfonium) elements suggests a complex solubility profile.
  • Solvent Type: The solubility is likely to vary significantly between different solvents. For instance, it may dissolve better in polar solvents such as methanol or water due to the quaternized nitrogen atom in the benzimidazolium moiety.
  • pH Sensitivity: The solubility might change with pH, as protonation states of amines could affect interaction with solvents, particularly in aqueous solutions.
  • Temperature: As with many compounds, increased temperature may enhance solubility, especially if the interactions are primarily hydrogen bonds or van der Waals forces.

Generally, users should refer to empirical data to determine the precise solubility characteristics under specific conditions. "Solubility is not just a property; it’s a gateway to understanding reactivity and application." Therefore, it is crucial to investigate solubility thoroughly for practical applications, especially in pharmacology and materials science.

Interesting facts

Interesting Facts about 4-[[3-[2-(diethylamino)ethyl]-1H-benzimidazol-3-ium-2-yl]sulfanyl]-N,N-diethyl-aniline

This intriguing compound is notable for its complex structure, characterized by a mixture of aromatic and aliphatic components. Its unique combination of a benzimidazole ring with a diethylamino substituent makes it a subject of interest in medicinal chemistry.

Key Highlights:

  • Diverse Applications: Compounds containing benzimidazole derivatives are often explored for their potential use in pharmaceuticals, particularly as anti-cancer agents and antifungal medications.
  • Electron-rich System: The presence of nitrogen atoms within the benzimidazole structure contributes to its ability to function as a nucleophile, making it reactive in various chemical reactions.
  • Intermolecular Interactions: The compound's ability to interact with biological targets can be attributed to its specific design which enables it to fit into biomolecular sites effectively.
  • Structure-Activity Relationship (SAR): Understanding how modifications to its structure affect biological activity can lead to the development of more potent derivatives.
  • Potential in Drug Discovery: The intricate design of this compound is an example of how multi-functional molecules can aid in the search for novel therapeutic agents.

Researchers are continuously intrigued by the potential of this compound and its relatives, as they explore how variations can lead to enhanced efficacy in targeting diseases. As a chemistry student or researcher, delving into the synthesis and applications of such compounds opens doors to exciting discoveries in the realm of medicinal chemistry!